"Zoixon": instructions for use. Drug "Zoixon": reviews

Today, many patients are prescribed a drug called Zoxon. Instructions for use, indications and contra-indications, the price and availability of analogues are just those questions, answers to which many people are looking for.

Composition and form of the drug

This drug is available in the form of round flat tablets of white color (sometimes with a slight yellowish tinge). The main active substance is doxazosin in the form of mesylate. Each tablet contains 1, 2 or 4 mg of this component.

In addition, some auxiliary substances are present here, in particular granular microcrystalline cellulose, lactose, colloidal anhydrous silicon dioxide, magnesium stearate, sodium carboxymethyl starch and sodium lauryl sulfate.

Tablets are packed in blisters of 10 pieces. In one package there may be 3, 9 or 10 such blisters.

Pharmacological properties

The active component of the drug (doxazosin) is a selective blocker of alpha-1-adrenergic receptors. Such drugs have a positive effect on urodynamics in patients with prostatic hyperplasia. This effect is due to the blockade of alpha-1-adrenoreceptors, which are located in the tissues of the neck of the bladder, as well as the capsule and stroma of the prostate itself.

In addition, the drug leads to a decrease in blood pressure, as it reduces the overall peripheral vascular resistance. Also, this agent positively affects the level of lipids in the blood, since it significantly reduces the concentration of cholesterol and triglycerides. Thus, the drug also prevents the development of coronary heart disease. "Zoxon" leads to a decrease in the degree of hypertrophy of the left ventricle, inhibits platelet aggregation and reduces the likelihood of blood clots. At the same time, the drug does not have any negative effect on metabolic processes.

After taking the pill rather quickly dissolves and absorbed by the walls of the digestive tract. The maximum concentration of doxazosin in the blood is observed after 1-2 hours after administration. The active component binds to plasma proteins by about 98%. The half-life is 22 hours. Metabolites are excreted from the body mainly along with the calves.

Indications for use

Many readers are interested in the question of in which cases it is advisable to take Zoxon. Tablets are most often prescribed to patients suffering from benign prostatic hyperplasia (prostatic adenoma). In particular, the drug helps to eliminate urination disorders caused by compression of the bladder and urinary tract (imperative urges, a feeling of not fully emptied bladder, frequent nocturnal urges, etc.).

In addition, indications for use are arterial hypertension (high blood pressure). By the way, if a patient suffers from both hyperplasia and hypertension, the pills act immediately in both directions. At normal pressure, taking the drug does not cause it to change.

"Zoxon" preparation: instructions for use

It should be noted immediately that only a specialist can prescribe such a medicine. The doctor knows how to take Zoxon tablets correctly. Instructions for use say that the dosage depends on the problem that is found in the patient, and the general condition of his body.

For example, with prostate adenoma, as a rule, the daily norm is 2-4 mg (1-2 tablets). The drug should be taken once a day, without chewing, but always with enough water. The maximum daily dose is 8 mg.

The scheme of treatment with hypertension looks quite different. As a rule, first 1-2 mg of the active ingredient is prescribed to the patient. At the first reception of the patient it is desirable to put in bed, as the first dose of the medicine can cause some side effects - this is perfectly normal. Then the amount of the drug is gradually increased to achieve the maximum therapeutic effect - in most cases, patients need a dose of 8 mg. The maximum daily amount, which in no case can not be exceeded, is 16 mg.

The duration of therapy is determined by the attending physician, but the tablets are suitable for long-term use. In most cases, the treatment lasts about a month, after which you need to take a break. During therapy, you can not drive a car, and also drink alcoholic beverages.

Contraindications to therapy

Of course, the important question is whether all patients can receive Zoxon. The instruction says that some medications still have some contraindications.

To begin with, we should note that the drug should not be taken to patients with increased sensitivity to doxazosin, quinazoline derivatives, and the rest of the tablets. Also, the drug is not used to treat children and adolescents under the age of 18.

Relative contraindications include pregnancy and lactation. The results of the conducted studies show that the preparation does not have an embryogenic or teratogenic effect. Nevertheless, its effect on the fetus is not fully understood. The medicine can be taken only if the benefit to the mother organism exceeds the possible risk for a growing child.

The medicine "Zoxon" is very carefully used for the treatment of patients suffering from orthostatic hypotension, aortic or mitral stenosis, as well as from various violations of the liver.

Side effects and possible complications

Can you take any complications taking Zoxon tablets? Instructions for use indicate that some adverse reactions are possible, and they depend on the patient's problems. For example, in people suffering from high blood pressure, the first use of the drug may cause orthostatic hypotension. Side effects also include dizziness, asthenia, fatigue, headaches, swelling, persistent drowsiness, nausea.

In patients with benign hyperplasia, all the above symptoms may also occur. In addition, some men complain of increased excitability, priapism, dry mouth. Sometimes, therapy can lead to the development of gynecomastia, increased activity of hepatic enzymes, jaundice. There is rarely alopecia, various disorders of the kidneys, as well as arthralgia, weakness in the muscles, convulsions, blurred vision, tinnitus, shortness of breath, cough, bronchospasm. If hypersensitivity to the components of the drug may cause an allergic reaction, which is accompanied by skin rashes, redness, itching and swelling.

Very rarely, taking medication causes such severe complications as angina pectoris, myocardial infarction, cerebral circulation disorder.

Overdose and its main symptoms

Many patients are interested in the question of whether an overdose of Zoxon is possible. The instruction indicates that such cases are actually registered. Taking too much of the drug leads to a sharp drop in blood pressure, which is sometimes accompanied by loss of consciousness.

In such cases, the patient should be placed on his back, lifting his legs and head down, then call an ambulance. As a rule, first the gastric lavage is done, after which the patient is assigned activated charcoal or other sorbents. In the future, symptomatic therapy is performed.

"Zoxon" preparation: analogs and substitutes

For one reason or another, this medication is not suitable for every patient. And in such cases, the first question is whether it is possible to replace the drug "Zoixon" with something.

Analogues of the drug, of course, exist. For example, such drugs as Prostamed, Vitaprost and Prostasabal are widely used to normalize the outflow of urine in medicine. But the preparation "Finast" not only eliminates problems with urination, but also helps to reduce the size of the prostate gland. Analogues include such medicines as Cardura, Proscar, Penester, Adenostop, Speman Fort, and many others. Some drugs are cheaper, while the price of other drugs is much higher. In any case, you can not select an analogue yourself - this can only be done by the attending physician.

How much is the medicine?

Of course, the issue of cost is important for every patient. So how much will the "Zoxon" tablets cost? The price, of course, will depend on many factors. In particular, in consideration it is necessary to take the firm-manufacturer, the city of residence, the financial policy of the pharmacy, etc.

On average, 30 tablets with a dosage of 1 mg will cost you 210-270 rubles. At the same time, the same package of thirty tablets, but with a dose of active substance 2 mg costs about 320-400 rubles. By the way, in most cases, one pack is enough for the whole course of treatment.

Reviews of patients and doctors

Of course, many patients are interested in the question of what professionals and patients really think about the Zoxon drug. The doctors' comments are positive - the medicine really copes with its main task, normalizing urination with various diseases of the prostate gland. Moreover, the pills help maintain blood pressure, which is very important, given the fact that most often the elderly suffer from prostate diseases.

Patients also leave positive feedback. According to them, the effect of tablets appears only a few days after the start of therapy. The drug really improves the quality of life of sick men. Convenient is that the drug should be taken only once a day. And its cost is quite affordable, which is also an indisputable advantage.