Means "Preductal". Indications for use

Tablets "Preductal" instruction describes as a drug that improves metabolism in the myocardium and neurosessory organs in ischemia. The active substance is trimetazidine hydrochloride.

Mechanism of action

The "Preductal" agent, the indications for use of which will be described below, promotes the normal functioning of ion channels in membranes. The medication also provides for the transport of sodium and potassium ions, maintenance of cell homeostasis. The drug reduces the size of the lesions of the myocardium, without having a direct effect on hemodynamic parameters. Against the background of angina, the drug promotes an increase in the coronary reserve, thus slowing the onset of ischemia, triggered by physical overstrain. The drug provides a limitation of fluctuations in blood pressure, without a significant change in the frequency of cardiac contractions. In patients with ischemic dysfunction, when taking medication, there is an improvement in contractility in the left ventricle.

The drug "Preductal". Application. Price

The cost of medicine in pharmacies from 700 rubles. At what pathologies is the "Preductal" agent prescribed? Indications for the use of this medication are: IHD, cochlear-vestibular disorders of ischemic nature (tinnitus, dizziness and others). The drug is recommended to prevent attacks of angina pectoris (in combination with other drugs or as a mono-drug). For chorioretinal vascular disorders with the ischemic component, the drug "Preductal" is also prescribed. Indications for use, the severity of the course of the pathology, as well as the patient's tolerance are the main criteria in determining the duration of the medication.

Dosing regimen

The drug is taken with food. It is advisable to take the medicine in the morning and evening hours. The recommended dose is 1 tablet. 2 p / day. The drug should not be chewed or crushed. The duration of therapy or prevention is established by the specialist personally.

Side effects

The drug "Preductal", the indications for which are given above, can provoke a number of complications. In particular, on the basis of therapy or prevention, abdominal pain, indigestion, constipation, vomiting and nausea are noted. Patients can develop asthenia, develop dizziness, tremors, headaches. To undesirable consequences include various motor disorders (reversible, usually after discontinuation), sleep disorder. A common side effect is an allergic reaction, manifested by a skin rash, irritation, urticaria. In some cases, angioedema may occur. On the basis of medication, likely extrasystole, tachycardia, palpitation, orthostatic hypotension with dizziness, general weakness, loss of balance.

Contraindications

Do not prescribe medication to patients with renal insufficiency, hypersensitivity, Parkinson's disease, motor disorders associated with the syndrome of restless legs. It is not recommended for patients under 18 years of age. The expediency of using the drug during pregnancy or during the period of feeding is determined by a specialist.