"Bactrim" preparation: instruction

The drug "Bactrim" is a combined antimicrobial agent with a wide spectrum of action, the active substances of which are trimethoprim and sulfamethoxazole.

It is produced in such forms: syrup; Suspension for internal reception, separately for adults and for children; Tablets, separately for children and adults; Coated tablets; Concentrate used for the preparation of infusion solutions.

Pharmacological action of the drug "Bactrim" instruction for its use describes thus: the active substances contained in this drug, violate intracellular metabolism in a bacterial cell. The bactericidal activity of this medicine is manifested against various types of streptococci, staphylococcus, nisery, escherichia, salmonella, cholera vibrio, anthrax bacillus, bordetella, enterococcus, listeria, nocardia, protea, chlamydia, toxoplasm, morganella, plasmodia, pathogenic fungi and many others.

The duration of the therapeutic effect of the dose taken is seven hours.

Indications for taking the drug Bactrim instruction lists the following: infections of the genitourinary sphere (cystitis, urethritis, pyelitis, pyelonephritis, prostatitis, epididymitis, male and female gonorrhea, venereal lymphogranuloma, soft chancroid, inguinal granuloma), respiratory system infections (both acute And chronic bronchitis, bronchiectasis, bronchopneumonia, croupous and pneumocystis pneumonia), infections of the ear, throat and nose (sinusitis, otitis media, laryngitis, sore throats), scarlet fever, digestive tract infections (paratyphoid, abdominal Typhoid, cholera, salmonella, dysentery, cholera, cholangitis, cholecystitis, gastroenteritis that caused enterotoxic strains of Escherichia coli), infectious soft tissue and skin lesions (furunculosis, acne, pyoderma), acute and chronic osteomyelitis, wound infection, various osteoarticular Infections, acute brucellosis, South American blastomycosis, toxoplasmosis (as part of complex therapy), malaria.

Contraindications to the use of this drug are: hypersensitivity to the components of this drug and to all sulfonamides in general, renal and / or liver failure, anemia aplastic, anemia associated with vitamin B12 deficiency, leukopenia, glucose-6-phosphate dehydrogenase deficiency, agranulocytosis, breast-feeding period , Pregnancy, pneumocystis pneumonia, for the / m introduction - the age of up to six years, children, patients with hyperbilirubinemia.

With caution to prescribe the drug "Bactrim" instruction for its use recommends for bronchial asthma, various pathologies of the thyroid gland, deficiency in the body of folic acid.

Side effects of this medication are:

1. From the nervous system - from headaches to aseptic meningitis and peripheral neuritis.
2. From the side of the digestive tract - from nausea to hepatonecrosis and pseudomembranous enterocolitis.
3. From the hematopoietic system - from leukopenia to megaloblastic anemia.
4. From the urinary organs - from polyuria to anuria.
5. Also arthralgia, myalgia, various allergic manifestations.

Local reactions to the introduction of the drug "Bactrim" instructions for use lists such: thrombophlebitis at the site of intravenous administration and soreness at the site of intramuscular injection.

In case of an overdose - gastric lavage, intramuscular injection of five to fifteen mg per day of calcium folinate, up to hemodialysis.

Dosage and methods of using the drug "Bactrim" instruction for its use leads to the following:

1. Tablets are prescribed to children from the age of twelve and adults nine hundred and sixty milligrams once a day or four hundred and eighty milligrams twice a day, if the infection is severe, then four hundred and eighty milligrams three times a day. Children from one to three years - one hundred and twenty milligrams twice, two to six years - from one hundred twenty to two hundred forty milligrams twice, six to twelve - from two hundred forty to four hundred and eighty milligrams twice.
2. Suspension is given to children aged three to six months - one hundred and twenty milligrams twice, seven months to three years old - from one hundred twenty to two hundred forty milligrams twice, four to six years from two hundred forty milligrams twice to four hundred and eighty milligrams twice, from Seven to twelve years - four hundred and eighty milligrams twice, adults and children after twelve years - nine hundred sixty ml twice.
3. The drug "Bactrim Syrup" is prescribed to children from one to two years for one hundred twenty ml twice, from two to six years - one hundred and eighty and two hundred forty milligrams twice, six to twelve years - two hundred forty and four hundred and eighty milligrams twice.
4. Parenterally intramuscularly - adults and children over the age of twelve - four hundred eighty milligrams twice, children from six to twelve - two hundred and forty milligrams twice. Parenterally intravenously - children over twelve and adults - from nine hundred sixty to one thousand nine hundred twenty milligrams twice, children six to twelve - four hundred and eighty milligrams twice, six months to five years - two hundred and forty milligrams twice, six weeks to five months - One hundred and twenty milligrams twice.

The duration of therapy is established by the attending physician.