When do prednisolone injections?

Prednisolone is a semisynthetic glucocorticoid drug based on hydrocortisone. That is, it is a means with a high degree of biological activity that allows the use of Prednisolone injection in clinical situations. For example, when providing immediate assistance in emergency conditions.

Anti-allergic, anti-inflammatory, immunosuppressive action, the ability to increase the sensitivity of beta-adrenergic receptors (these are proteins of the outer cell membrane that recognize and bind synthetic analogues of catecholamines with adrenaline and noradrenaline) to endogenous catecholamines (i.e., active substances that function as chemical "control" molecules (neurohormones ) And intermediaries in intercellular interactions) are the main functions of the drug "Prednisolone". Ampoules for injections are available in a volume of 25 mg.

Urgent conditions, such as acute allergic reactions, thyrotoxic crisis, asthmatic status in bronchial asthma, shock that does not respond to standard therapy (surgical, burn, toxic or anaphylactic, traumatic or cardiogenic), acute renal or hepatic insufficiency, acute adrenal insufficiency, are Indication for the use of the drug "Prednisolone".

The injections are also prescribed for rheumatic diseases (rheumatoid arthritis or systemic lupus erythematosus), acute hepatitis and cirrhosis of the liver, bronchial asthma, and also to reduce inflammation and prevent the appearance of scar tissue and vessel constrictions during poisoning with cauterizing fluids.

Dosage and duration of treatment is determined by the doctor individually, depending on the severity of the disease and indications for the drug "Prednisolone". The injections are injected intravenously via droppers (first jet, then drip) or by intramuscular injection if intravenous injection is not possible. After the acute condition has been stopped, prescribe Prednisolone in oral tablets. At the same time, the dosage gradually decreases. If the course of treatment is long, then do not stop the therapy suddenly.

This drug is effective, but it has enough contraindications and side effects. First about the contraindications of the drug "Prednisolone". The injections are not applied even for vital signs, if there is intolerance or hypersensitivity to the constituent components. The drug should be administered with caution in cases such as recent or existing infectious diseases of the viral nature, gastrointestinal diseases, the vaccine period (as well as eight weeks before and two weeks after vaccination), immunodeficiency states.

With cardiovascular, endocrine diseases, severe chronic hepatic or renal failure, systemic osteoporosis, caution should also be taken with prednisolone. Pricks during pregnancy, especially in the first trimester, as well as children in the period of growth, are applied only according to vital signs and strictly under the supervision of the attending physician. If the drug is prescribed during lactation, breastfeeding should be stopped.

Among the side effects of Prednisolon is a decrease in the ability of the body to use glucose as a source of energy, suppression of adrenal function, steroid diabetes, increased intracranial pressure, steroid duodenal ulcer and stomach, increased blood pressure, bradycardia (sometimes to cardiac arrest), increased calcium excretion, Development in children, trophic changes in the cornea. And this is not all the side effects. A complete list must be read in the instructions for use of the drug "Prednisolone".