Xizal: analog, instructions for use, price, reviews

What is the Xizal medication? An analogue of this drug, its indications, instructions for use, price, form of release and composition will be presented below. Also, we will tell you about whether this medication has side effects and contraindications.

Composition, description, shape and packaging

What substances does the Xizal medication contain? Instructions for use (analogues of this agent may have the same composition) states that the active substance of this drug is levocetirizine dihydrochloride. As additional substances, this preparation contains sodium acetate, purified water, sodium saccharinate, propyl parahydroxybenzoate, propylene glycol, methyl parahydroxybenzoate, 85% glycerol and acetic acid.

In what form is the Xizal medication manufactured? Analogues are cheaper and the drug itself can be purchased in the form of tablets. Their film shell consists of a dropping Y-1-7000 and macrogol 400. They are sold in blister packs of 7, 14, 10 or 20 pieces in one carton.

In addition to tablets, there is another form of this drug. Drops for ingestion are issued in bottles of dark color with a dispenser of 20 and 10 ml.

Pharmacological action of the drug

How does the Xizal drug work? Cheap analogs and more expensive have the same effect. According to specialists, this medication is a remedy with a pronounced antihistamine and anti-allergic effect. The blocking effect of this drug on histamine receptors is several times higher than that of Cetirizine.

It should be specially noted that this medication has no effect on the antihistamine phase of the allergic reaction. The principle of this drug is that it is able to prevent the development of allergies. If such a state is necessary, the drug significantly facilitates its course.

What other properties does the Xizal medication have? An analogue of this drug and the drug itself has antipruritic and antiexudative action. The active substance of this drug slows the movement of eosinophils, lowers the permeability of the walls of blood vessels, and also reduces the activity of cytokines and inflammatory mediators.

At the cholinergic and serotonin receptors, this drug has virtually no effect. Also, he has no sedative effect.

Pharmacokinetic features of an antihistamine drug

How long does the drug "Xizal" take? Instructions for use (price reviews, analogs of this product are presented a little further) indicates that when taken orally the drug is absorbed quickly from the digestive tract. In this case, there may be an insignificant metabolism of its active substance.

If you take the medicine with food, then the level of its bioavailability, as well as the rate of absorption does not change at all.

The highest concentration of levocetirizine in the blood is noted 60 minutes after taking the drug inside. As practice shows, the clinical effect of this remedy is saved just over 24 hours.

The half-life of the drug in adults is 6-10 hours, and in young children - slightly less.

Approximately 13% of the drug comes out of the body through the intestine, and 85% - with the help of the kidneys.

In patients with people who suffer from kidney failure, the half-life of the drug is noticeably lengthened. As for patients on hemodialysis, only 10% of the active substance is excreted.

It should also be noted that the main component of the drug can easily penetrate into the mother's milk.

Indications for use of the drug

What is the use of the Xizal medication? Analogue means and the drug itself is prescribed under such conditions as:

• The presence of itching;
• Angioedema;
• nasal congestion;
• Sneezing;
• Pollinosis;
• Lacrimation;
• Inflammation of the mucous membranes of the eye and nose (for example, with conjunctivitis);
• Rhinorrhea;
• Chronic or seasonal conjunctivitis, as well as rhinitis of allergic origin;
• Urticaria, flowing in chronic form;
• Dermatoses are allergic.

Contraindications to the use of medicinal product

Under what conditions can not apply the medicine "Xizal"? The analogue of the mentioned agent and the drug itself are contraindicated to people with increased sensitivity to the active substance, as well as to other elements that make up the drug. It should also be noted that the drug "Xizal" is not prescribed for people with renal insufficiency (especially with a pronounced).

During the lactation and during pregnancy, taking this medication is also contraindicated.

Xizal preparation: instructions for use

Analogues, patients' comments about the mentioned medicine, we will present at the very end of the article. With regard to this section, in it we will tell you about how and in what dosage should take such a drug.

Before taking a drop of Xyzal, dilute it in warm drinking water (10 ml), then take it with a teaspoon.

Consider the dosage of medicinal drops:

• To children 2-6 years old the preparation is given on 5 drops twice a day;
• Children from 6 years old, as well as adult patients are prescribed up to 20 drops per day (can be taken at one time).

As for the Xizal tablets, adult patients and children over 6 years of age should be taken on an empty stomach or with food. In this case, the drug should not be chewed. It's just washed down with plain water. The dosage of this form is as follows: 1 tablet once a day.

Signs of a drug overdose

What symptoms can occur if you take higher doses of Xizal? Analogues are cheaper and more expensive, and the medication itself can cause such undesirable symptoms as drowsiness, excitability, increased irritability and anxiety, which turns into drowsiness.

With such symptoms, the patient needs to wash the stomach or provoke vomiting. After this, it is required to prescribe symptomatic and supportive therapy.

A special antidote for poisoning with such a drug does not exist.

Adverse reactions after taking the drug

The most common side effects that occur when taking medication include fatigue, drowsiness, dry mouth, headaches, asthenic syndrome and abdominal pain.

Very rarely, patients experience such undesirable reactions as diarrhea, visual impairment, hallucinations, nausea, pruritus, seizures, dyspnoea, urticaria, muscle pains, rash, dyspnea, tachycardia and hepatitis.

There are also isolated cases of weight loss, angioedema and anaphylactic shock.

Drug Interactions

With the joint use of the drug "Xizal" with "Theophylline" may increase the half-life of levocetirizine.

It is highly not recommended to drink alcoholic beverages during therapy with this drug, as well as medicines that depress the central nervous system. This is due to the fact that such a combination can cause uncontrolled amplification of their effects.

The drug "Xizal": instruction, the price in pharmacies, analogues

Now you know what is meant for such a drug as Xizal. His instructions for use and dosages have been described in detail above. Now I want to tell you about how much this drug costs in pharmacies.

You can buy medicine in tablets for 250-290 Russian rubles (1 pack of 7 tablets). If you need to buy 10 pieces, then you have to give about 270-360 rubles. The cost of packing of 14 tablets varies between 430-530 rubles.

As for drops for oral administration, they are in the range of 350-420 rubles.

Now you know how much the drug "Xizal" costs. The price (analogous to the medicament we will consider right now) of this medicine is exemplary and can vary depending on the place of your residence and the pharmacy network.

If this remedy is contraindicated to you, you can replace it with one of such drugs as Suprastinex, Eltset, Glencet, Aleron, Cesera, or Alerzin (after consulting a doctor). Almost all of them are cheaper than the original (up to 230 rubles).

Patients' comments about the drug "Xizal"

There is a huge amount of feedback about the drug "Xizal". People who take this medication with allergic reactions claim that this is the most effective and effective remedy. Also, patients note its relatively low cost and convenience of admission.

In addition to positive, negative drugs are also left about the medicine in question. Some patients who take Xizal, speak of his strong sleeping pills. However, experts argue that this phenomenon can occur only when taking high doses of medication. But, despite this, during treatment with this drug should be extremely careful while driving vehicles or working with complex mechanisms.