"Tizin Alerji": reviews. Drops in the nose "Tizin Alerji": instruction, price

What do patients say about the drug Tizin Alergi? Comments on the medication will be presented at the end of the article. From it you will learn about the form in which the product is manufactured, how much it costs, what substances it contains and what properties it possesses.

Composition, description, shape and packaging

Drops in the nose of "Tizin Alerji" are a homogeneous suspension of white color. The active substance of this drug is levocabastine hydrochloride. In addition, the preparation also includes additional ingredients such as sodium hydrogenphosphate, propylene glycol, hypromelose, sodium monohydrate, polysorbate, benzalkonium chloride, purified water and edetate disodium.

Drops "Tizin Alerji", the instruction to which is enclosed in a cardboard box, are issued in 10 ml vials. They are made of polyethylene, and also equipped with a spray (for ease of use) and a special protective cap.

Pharmacology means

The drug "Tizin Alergi", the price of which is indicated below, is an antiallergic drug. According to the instruction, such drops have a direct effect on selective blockers of H1-receptors (histamine).

After applying the medication, the patient disappears almost all the symptoms of rhinitis, which are allergic. Also, this drug eliminates itching and discharge from the nose. In addition, it prevents sneezing attacks.

Few people know, but the drops of "Tizin Alerji" can be used not only for instillation in the nose, but for the eyes. As a rule, in ophthalmic practice they are used for allergic conjunctivitis.

According to the experts' feedback, the effect after the application of this medication comes in about 5 minutes and lasts for 12 hours.

Pharmacokinetics

When intranasal administration of the drug (in an amount of 50 μg) absorbs about 30-35 μg of levocabastine. Its maximum concentration in the blood is approximate after three hours.

The binding of the active substance to plasma proteins is about 55%. The main metabolite (acylglucuronide) of the drug is formed in the process of glucuronization.

The half-life of a substance such as Levocabastine is 37-40 hours. It is excreted by the kidneys (mostly unchanged).

Indications

What is the purpose of using the medicine "Tizin Alerji"? Reviews say that such drops effectively manifest themselves in allergic rhinitis and conjunctivitis. Also, this medication is prescribed for exacerbation of pollinosis and rhinoconjunctival syndrome.

Contraindications

What kind of contraindications should you know before using Tizin Alergi's medication? Medical experts say that this drug is forbidden to prescribe when the patient is hypersensitive to the active and additional substances that make up the drops.

Also, this drug is not used to treat children under the age of 6 years.

With extreme caution, nasal and eye drops are recommended for older people and those who suffer from kidney failure.

Tizin Alergi drops: instructions for use

How should I use the drug in question? It is administered intranasally. Children older than 6 years and adults are advised to use 2 doses of medication (ie 100 mcg) in each nasal passage twice per day.

Use of this medication should continue until all signs of the disease have been eliminated. With severe symptoms of the disease, the drug can be used four times a day.

Before using the medication, the patient is advised to clean the nasal passages from the existing secretions and take a deep breath (through the nose) during the treatment procedure.

Mode of application

How to instill the drug "Tizin Alerji"? Reviews say that before the first use of this product, you need to remove the protective cap, and then press the nozzle several times. As a result of this spraying, a cloud of "fog" should form in the air. Then the nozzle should be inserted into the nasal passage and press. At the same time, you need to inhale through your nose.

Before the next use of drops, the vial should be shaken thoroughly.

Side effects

Unfortunately, the drug in question quite often causes side effects. They include the following:

• Nausea, drowsiness;
• Dryness, discomfort at the injection site, burning;
• Pain in the larynx and pharynx, cough, nosebleeds;
• Edema of the nasal mucosa, bronchospasm;
• Tachycardia, allergic reactions;
• Headaches, dizziness;
• Fatigue, local short-term irritation;
• malaise.

An overdose of the drug

There were no reports of overdoses by the drug in question. However, experts believe that with the occasional taking of drops inside the patient are possible: a decrease in blood pressure, a small sedative effect and tachycardia.

To eliminate such symptoms, the victim needs to drink plenty of water in order to speed up the removal of Levokabastin by means of the kidneys.

Drug Interactions

In clinical studies of the interaction of this drug with ethanol was not noted. Also, the enhanced effects of "Diazepam" with simultaneous application of nasal drops "Tizin Alergi" in usual dosages were not revealed.

The combination of this drug with "Erythromycin" and inhibitors of CYP3A4 isoenzymes of ketoconazole does not affect the kinetics of levocabastine.

Local interaction of this drug with other intranasal preparations has not been studied, except for its interaction with "Oksimetazolinom." By the way, the latter reduces (transiently) the absorption of nasal drops "Tizin Alerji".

Special Recommendations

The drug "Tizin Alergi" (the instruction of this medicine is obligatory for reading) does not have a pronounced sedative effect, nor does it reduce the speed of the reaction.

When there is drowsiness, the patient is not recommended to engage in hazardous activities, as well as get behind the wheel of vehicles.

After the expiry date of the drug, it should not be thrown out onto the street or drained into sewage. The drug should be placed in a bag and put in a garbage container.

Cost and analogues of medicament

How much are the drops of Tizin Alerji? The price of this medication is not very high. You can buy it for 210-280 rubles.

As for the analogs, they are not very many. Similar drugs have such drugs as Vizin Alerzhi, Histimet, Levokabastin, Reaktin. However, replacing them with the drug "Tizin Alerji" follows only after consulting a doctor.

Reviews about the drug

Most patients who have ever used this drug leave only positive reviews about it. They report that this drug shows itself well when there are symptoms of allergic rhinitis and allergic conjunctivitis.

After using this medication, patients immediately stop nasal discharge. In addition, this drug prevents sneezing.

As for the minuses, they include the inability to apply drops during pregnancy and during breastfeeding. Also, many people complain that this drug can not be used by children under six.