Preparation "Alerzin": instructions for use, composition, description and reviews

In our time, a huge number of people suffer from allergic diseases. They can appear completely differently. Someone begins a long rhinitis, someone is tortured by rashes all over the body, and someone can not cope with his cough. There are many medicinal products against this disease, they all have their own peculiarities of application and indications for use. One of such medicines is "Alerzin". The instruction attached to it contains a detailed description of indications and contraindications.

Structure of the preparation

"Alerzin" is available in two dosage forms: in the form of tablets and drops. If we consider drops, then 1 ml of the drug includes:

• 5 mg of levocetirizine dihydrochloride is the main active ingredient.
• As auxiliary substances there are: 85% glycerol, sodium saccharin, propylene glycol, sodium trihydrate acetate, propyl parahydroxybenzoate, glacial acetic acid, methyl parahydroxybenzoate, purified water.

In 1 tablet contains also 5 mg of active substance, and as additional components are included:

• Microcrystalline silicon cellulose.
• Lactose monohydrate.
• Low substituted hydroxypropylcellulose.
• Magnesium stearate.

Drops are produced in 20 ml vials, and tablets are packaged in a pack of 7-14 pieces.

Pharmacological action and pharmacodynamics

In its properties, the drug belongs to antihistamine drugs. The main active component, if we consider "Alerzine" (drops), the instruction for use describes how to block the receptors of histamine.

The effect of the drug is possible due to:

• Reduced permeability of blood vessels.
• Reduced migration of eosinophils.
• Restriction of the release of inflammatory mediators.

The active substance of the drug does not allow the development of allergic manifestations, due to the fact that it has the following properties:

• Antiexsudative.
• Anti-inflammatory.
• Antipruritic.

Taking the drug inwardly leads to its rapid absorption into the bloodstream, and this process is virtually independent of food intake. Bioavailability of the drug is 100%.

Efficacy is manifested in some patients already in 12-15 minutes after administration, in the majority - in half an hour or an hour. Precise information about the distribution of matter in the tissues of the body is not available.

Indications for use of the drug

Concerning means "Alerzin" the instruction contains the information on indications to application. It is usually recommended in the following situations:

1. Treatment of symptoms in patients who suffer from chronic idiopathic urticaria.
2. As a medicine for rhinitis caused by allergens.

The list of indications is small, judging from the information that the "Alerzin" instruction informs. Reviews about him are good enough if you follow all the doctor's recommendations for use.

Who should not take "Alerzin"

No matter how good a preparation is, it necessarily has contraindications. In "Alerzin" they are as follows:

1. Do not take medicine for patients with severe kidney disease.
2. During the period of breastfeeding, women are not prescribed a drug.
3. If there is an individual intolerance to the components of the drug.
4. During pregnancy.
5. In the presence of lactose deficiency.
6. There is intolerance to galactose or disruption in the process of assimilating glucose and galactose, but this only applies to the tablet form.
7. Particular care should be taken when appointing elderly patients.

Alerzin: instructions for use

Given the different form of release of the drug, the dosage and treatment regimen will differ. These nuances need to be clarified by the doctor.

If the "Alerzine" (drops) is prescribed, the instruction recommends taking them inside without taking into account the intake of food. You can use the drug both in pure form and diluted with water. Do not store diluted drops, they must be consumed immediately.

The dosage is chosen by the doctor, but usually it is 5 mg once a day.

If the pharmacy offers you "Alerzin" (tablets), the instruction recommends taking them whole by washing down with water. Dosage is also 5 mg or 1 tablet per day.

Duration of treatment

If allergic rhinitis occurs periodically and lasts from 4 days to a month, then therapy with "Alerzin" is necessarily coordinated with the peculiarities of the course of the disease. Often with the disappearance of symptoms, treatment can be stopped, and if they arise - again to resume.

If allergic rhinitis lasts more than a month as a result of constant contact with allergens, then therapy can be permanent. With the chronic form of urticaria and rhinitis, treatment with Alerzin can last about a year.

Side effects of the drug

Not all patients tolerate the effects of this medication well. The organism at all different, therefore it is possible to expect some undesirable displays which can mention many systems of organs:

1. Shortness of breath may appear on the part of the respiratory system.

2. The nervous system can respond with the following symptoms:

• Sleep disturbance.
• Headache.
• Fast fatiguability.
• Increased agitation.
• Weakness.
• Asthenia.
• Convulsions.
• Dizziness, down to fainting.
• Tremor of extremities.
• Hallucinations.

3. From the side of the cardiovascular system, you can observe increased heart rate and tachycardia.

4. The urinary system will show its malfunction in the form of a delay in urine, dysuria.

5. Visual disturbances may occur.

6. Disorders from the gastrointestinal tract in the form of nausea, diarrhea, constipation, dryness in the oral cavity, hepatitis.

7. Myalgia.

8. On the skin, rashes may appear, itchy itch, in some situations - Quincke's edema.

9. Rarely, there may be swelling, increased appetite, weight gain.

If any undesirable manifestations occur during therapy, "Alerzin" should visit a doctor and discuss with him further treatment.

Reception of increased doses of the drug

Some mistakenly believe that an increased dosage will give a positive effect faster and exceed the norm of taking the medicine. This leads to an overdose of the active substance in the body, which can provoke:

• Drowsiness.
• Increased irritability.
• Nerve agitation.

All these manifestations will depend on the amount of the drug taken in excess of the norm. In case of an overdose, it is necessary to clean the stomach, and then eliminate the symptoms.

Interaction with other drugs

We examined the drug "Alerzin", the instruction, the price for it is quite acceptable, but it is necessary to discuss with the attending physician the combination of the drug with other drugs, if you use one.

Long-term laboratory tests have established that the joint intake of Alerzin and Antipyrine, Glipizide, Erythromycin, and Diazepam does not have negative consequences.

If you combine the drug and treatment with "Ritonavir", then the distribution of the latter on the body is reduced by 10-12%.

Joint application with "Theophylline" reduces the clearance of levocetirizine, but the kinetics of "Theophylline" does not change. During the period of therapy with Alerzin, taking sedatives is not recommended, although with the use of therapeutic dosages, no increase in their effect was observed.

Some indications during treatment "Alersin"

The doctor, before appointing any drug, should conduct a thorough examination of the patient. This also applies to quite safe means, to which can be attributed and Alerzin. In the presence of concomitant diseases, the dosage and treatment regimen should be adjusted.

Take the drug carefully in patients with pathologies of the excretory system, especially in elderly patients with CRF.

If a spinal cord injury is found in a patient, adenoma of the prostate gland, it is necessary to correct the dose of the drug, since it can provoke a delay in urine in the body.

Some components of Alerzin can cause allergic manifestations, so patients who are overly susceptible to various factors should be cautious during treatment.

Application of the drug in childhood

To use for the treatment of allergic rhinitis or urticaria in children should only after consulting a doctor, "Alerzin." Instruction for children does not recommend using it for the treatment of babies younger than 6 months.

The dosage of drops will depend on the age of the child:

• From 6 to 12 months a day, you can take 5 drops of the drug once.
• From 1 year to 6 years "Alerzin" (drops) instruction for children recommends giving 5 drops 2 times a day.
• Children older than 6 years, the dosage is 5 ml 1 time per day.

Tablets should not be given to children under 6 years of age. After 6 years a day, a dose of 5 mg, which equals 1 tablet.

Application of Alerzin during pregnancy and lactation

Women in an interesting situation is practically not appointed "Alerzin", the instruction does not contain reliable facts about the safety of levocetirizine for fetal development.

If there was a need for taking the drug during breastfeeding, then it must be stopped.

Drug analogues

Alerzin has a fairly large number of analogues, they have a similar therapeutic effect, so if there are contraindications to its use, then it is worth discussing this issue with a doctor.

Among the analogs we can mention the following:

• Allertec.
• "Zestra".
• The Zodak.
• Zirtek.
• "Rolinosis."
• "Cetrin."
• Cetirinax.

If there are no contraindications to the reception of Alerzin, then it is necessary to discuss with the doctor whether it is possible to replace it with an analog. In some cases, it is better to use that drug that has already been tested and gives a positive effect.

Reviews about the drug

The "Alerzin" (drops) has already been considered in detail, the instruction. The price of the drug is relatively small (about 330 rubles), so most patients can afford to buy it. Feedback on the treatment of this drug is positive, this is due to the rapid action, convenient use and high efficiency.

Some patients who apply the medication periodically, note one drawback - this is a short shelf life after the opening of the vial with droplets.

Allergy has quite unpleasant manifestations, from which you want to get rid quickly. The shelves of pharmacies are full of antihistamines, but the choice of a medicine is better entrusted to a specialist, and not self-medication, then the effect will be guaranteed.