HealthPreparations

Nicotinic acid instruction

Nicotinic acid, the instructions for use of which will be discussed in this article, is a vitamin that takes part in oxidative processes taking place in living cells and is a medicinal product. The medicine is presented in the form of a white powder with a sour taste and odorless. It is difficult to dissolve in cold water.

It should be said that nicotinic acid (or vitamin PP) is a vitamin, anti-allergic, detoxifying and hypolipidemic agent that promotes the improvement of carbohydrate metabolism, the expansion of blood vessels, including the brain, the transfer of oxygen into tissues. It participates in the processes of metabolism of fats, amino acids, proteins and purines, as well as in the processes of biosynthesis.

Nicotinic acid, the instruction to which provides for the use of vitamin up to twenty-five milligrams a day, at high doses (up to four grams per day) reduces the number of lipoproteins, triglycerides and cholesterol in the blood.

This drug is quickly absorbed from the digestive tract, and after forty minutes it turns into nicotinamide. The vitamin in the liver is metabolized, it is synthesized in the intestine, while it is excreted by the kidneys in the form of a metabolite.

Indications for the use of the drug are: avitaminosis, parenteral nutrition, malabsorption, rapid weight loss, impaired digestion of amino acids, GI disease, increased body requirement for vitamin PP, fever, hepatitis, infectious diseases that are chronic, as well as malignant tumors, pregnancy, Lactation, stress. Also nicotinic acid, the instruction on which application is applied to the drug, is prescribed for circulatory disturbances in the brain, diseases of the vessels of the extremities, including their spasms, diseases of the genitourinary system, polyneuropathy and microangiopathy.

Nicotinic acid contraindications have the following: hypersensitivity to the drug, gastric ulcer, gastritis, gout, glaucoma, hypotension, children under two years of age. Also, with caution use this drug for diseases of the facial nerves, colitis, enterocolitis, trophic and non-healing long period of time wounds.

Nicotinic acid has side effects as follows: Hyperemia of the skin, redness of the facial skin, dryness of the mucous membranes of the eyes and skin, as well as arrhythmia, dizziness, nausea and vomiting, skin itching, myalgia, hyperglycemia, paresthesia. All these phenomena can occur when taking large doses of the drug. If vitamin PP is used for a long time, liver dystrophy, facial hyperemia, asthenia, dizziness and headaches, an increase in the content of AST, APF and LDH in the blood can occur.

Use the drug after meals in the following dosages: adults - twenty-five milligrams per day, children over two years - up to twenty milligrams a day.

It should be remembered that nicotinic acid is used with caution in combination with anticoagulants and antihypertensive drugs. In any case, when used with other medicines, it is necessary to consult with a specialist.

In addition, the use of nicotinic acid requires a balanced diet (products containing methionine) and constant monitoring of liver function. For better digestion in the digestive tract, it is recommended that the preparation be taken with milk.

Thus, nicotinic acid, the instruction to which has been described above, is an indispensable medicinal product in the prevention and treatment of many diseases. It takes part in the metabolic and oxidative processes that occur in the body, as well as in the process of metabolism.

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