"Maxikold": instructions for use. Maxikold (spray): instructions for use for children

At the first symptoms of a cold, doctors recommend immediately taking a shock dose of analgesic. In the future it is required to maintain its immunity, and the infection will recede.

General information

What analgesics do you know? If you do not know which drug should be taken with a cold, then we will help you in this.

The most common and sought after remedy for the treatment of such diseases is the Maxikold drug. Instructions for the use of this medication, its contraindications, side effects and release forms will be discussed in this article.

Forms, composition, packaging and description

There are several forms of the drug in question. It can be purchased in the following types:

• Oral preparation "Maxikold" (tablets). Instruction for use reports that this medication has a pinkish-orange color, a film membrane and a biconvex oval shape. The active substances of this drug are paracetamol, ascorbic acid and phenylephrine hydrochloride. As auxiliary components, croscarmellose sodium, giprolose (hydroxypropylcellulose), calcium hydrophosphate, magnesium silicate, ethyl cellulose, talc, yellow dye "Sunset Sun" are used. The medication is issued in cell packs and cardboard boxes, respectively.
• Crystalline substance "Maxcold" (powder). Instructions for use say that this product has a specific odor and a light yellow color. It is admissible to have white crystals and decaying lumps. After dilution the solution is opalescent and has a pleasant aroma of orange. Active components of this agent are also paracetamol, ascorbic acid and phenylephrine hydrochloride. In addition to them, the powder also includes auxiliary ingredients (colloidal silicon dioxide, sodium citrate, sodium saccharin, potato starch, citric acid, lactose, flavor, yellow dye quinoline). The medicament in question is packed in sachets of 5 g (from the combined material) and sealed in cardboard packs.
• Aerosol Maxicold Lor (spray). Instructions for use indicate that the medication in question is a clear and almost colorless liquid that has a characteristic smell of menthol. Active substance of this agent is hexazetidine. As auxiliary components, sodium saccharinate dihydrate, glycerol, citric acid monohydrate, sodium hydroxide, lauromacrogol, ethanol, levomenthol, cineole, peppermint leaf oil and purified water are used as auxiliary components. The spray goes on sale in aerosol aluminum cylinders with a metering pump, which is equipped with a spray gun for oral use and a protective cap.

Pharmacological properties

What is the MaxiKold drug? Instructions for use indicate that this combination is an analgesic and antipyretic action designed to alleviate the symptoms of flu and colds.

According to experienced specialists, the effect of this drug is due to the properties of the substances that make up its composition.

• Phenylephrine is called alpha-1-adrenostimulant, which practically does not affect the beta-adrenoreceptors of the heart. Also, it is not catecholamine. This substance causes the narrowing of the arterioles, which greatly facilitates breathing, reduces flushing of the mucosa and edema of the nasal cavity.
• Paracetamol is a non-narcotic analgesic. It has antipyretic and analgesic properties, which are due to blockade of cyclooxygenase in the central nervous system and exposure to centers of thermoregulation and pain. This substance reduces fever, as well as muscle and headaches.
• Ascorbic acid helps to increase the body's resistance to infections, and replenishes the body's need for vitamin C, especially for flu and colds.

Pharmacokinetics

What kinetic parameters does the MaxiKold preparation have? Instruction for use states that each component of this product has its own absorption properties.

Paracetamol is absorbed from the intestine. Its maximum concentration is observed after 30-180 minutes. The connection with plasma proteins is 15%. Metabolism of this substance occurs in the liver. Its half-life period varies within 1-4 hours. The drug is mainly given up by the kidneys.

After taking the medicine inside, phenylephrine is badly absorbed from the digestive tract. Its metabolism occurs with the participation of monoamine oxidase in the walls of the intestine, as well as during the first passage through the liver. The bioavailability of phenylephrine is very low.

Vitamin C is absorbed from the digestive tract, mainly in the small intestine. Its highest concentration is observed after 4 hours. The drug quite easily penetrates into platelets and leukocytes, and then into all tissues of the body.

The maximum concentration of this substance is noted in the glandular organs, the lens of the eye, leukocytes and liver. It also penetrates the placenta. Metabolism of ascorbic acid is carried out in the liver, where it is converted into oxaloacetic and deoxy-ascorbic acid and ascorbate-2-sulfate. The excretion of vitamin C occurs through the kidneys, intestines, sweat and breast milk.

Indications for the use of a spray, powder and tablets

What is the purpose of the Maxikold drug (spray)? The instruction for use states that all forms of the drug should be used for the symptomatic treatment of inflammatory and infectious diseases. Also, this tool is used for influenza and ARVI.

Contraindications

What kind of human condition is forbidden to use the medicine "Maxcodd Reno"? Instruction for use indicates that any form of the agent in question is not assigned when:

• Arterial hypertension;
• Renal and hepatic insufficiency (expressed);
• Heart diseases (including acute myocardial infarction, severe stenosis of the aortic aorta and tachyarrhythmia);
• Hyperthyroidism, as well as thyrotoxicosis;
• Simultaneous administration of other drugs containing paracetamol, as well as funds designed to alleviate the symptoms of flu, colds and nasal congestion;
• Hyperplasia of the prostate gland;
• Simultaneous administration of monoamine oxidase inhibitors, beta-blockers and tricyclic antidepressants, including a period of 2 weeks after their withdrawal;
• Angle-closure glaucoma;
• Hypersensitivity to any of the drug substances;
• In children under 9 years of age, as well as with a weight of less than 30 kg.

With caution this medication is recommended for pregnant women, people with deficiency of glucose-6-phosphate dehydrogenase, and also during breast-feeding, with benign hyperbilirubinemia and in old age.

Maxikold Reno: instructions for use

Powder for preparation of medicinal solution in the amount of 1 packet is poured into a glass of hot boiled water and thoroughly stirred until the crystals dissolve.

Adult patients should not take this medication more often than every four hours. The maximum daily dose of this medicine is 4 packages per day.

Children should be given a powder every six hours and not more than 3 packs a day.

To avoid the development of adverse reactions, the drug in question should not be used for more than five consecutive days as an anesthetic and for more than three days as an antipyretic.

Method of taking and dosage of tablets

In what dose are the Maxiokold tablets prescribed? Instruction for use informs that this medication is taken orally before a plentiful meal or two hours after it (it is recommended to wash it with plain water).

For adolescents and adults, the drug is prescribed in the amount of 2 tablets every four or six hours.

The dose of medication for children 9-12 years old is 1 tablet with the same multiplicity.

According to specialists, this medication should not be taken for more than five consecutive days for anesthesia and more than three days for lowering the temperature.

Maxocold (spray): instructions for use

For children, aerosol is prescribed only after three years. In this case, the medication should be used only under the supervision of adults or a pediatrician.

So how should you use such a tool as Maxi-Law Lor? Instructions for use indicate that the drug in question is intended for local injection. Using aerosol, all affected areas in the pharynx and oral cavity are treated. The procedures are carried out in the intervals between meals.

How to inject Maxocold (spray)? Instructions for use indicate the need for the following:

• Remove the lid from the cylinder and install the nebulizer;
• When using the aerosol for the first time, it is required to make short-term pressures and direct the jet into the air;
• Insert the mouthpiece into the mouth and push the sprayer 2-4 times until it stops (hold your breath).

Side effects

Now you know how to use Maxi-Law Lor medication. Instructions for use were presented a little higher.

The use of the agent in question may contribute to the appearance of the following undesirable reactions:

• Violation of hematopoiesis;
• Migraine, nausea, decreased blood pressure, vomiting, increased blood pressure, irritability;
• Angina pectoris, palpitations, bradycardia, dyspnea, ventricular arrhythmia, tachycardia;
• Irritation of gastrointestinal mucosa, glucosuria, hyperacid gastritis, microangiopathy, urticaria, hyperprothrombinemia, hyperoxaluria, insomnia, erythropenia, neutrophilic leukocytosis, thrombocytosis and others.