"Gistak": instructions for use, description and reviews

To the doctor on reception people with different complaints come. Quite often it happens in connection with the problems in the work of the gastrointestinal tract. People in the bustle of modern times cease to watch what they eat, as a result, suffer from diseases that used to be much less common. Modern food, fast food, as well as all kinds of chips and crackers contain many food colors, additives and other ingredients that adversely affect the stomach. As a result, there is gastritis or peptic ulcer. One of the often prescribed drugs for the treatment of gastrointestinal diseases is "Gistak". Instructions for use, analogues and reviews about this drug will be discussed further.

How the drug works

The instructions for use are attached to each package of the preparation "Gistak". The photo below shows what the original medicine package looks like.

The drug "Gistak" refers to medicines, which by their action provoke a decrease in the production of gastric juice, proportionally decreasing the activity and the amount of pepsin. The active substance of the drug, ranitidine, refers to blockers of histamine H2 receptors of parietal cells. It is able to suppress the secretion of acid in the glands of the stomach, reduces pain syndrome. The manifestation of heartburn and the frequency of its occurrence decreases at times. The mucous membrane in the stomach activates its protective properties, heals ulcerative lesions, the tone of the lower gastroesophageal sphincter normalizes.

The drug "Gistak" lasts for twelve hours. After you have taken the medicine, the maximum concentration of the active substance will be reached in a couple of hours, and eating does not affect the absorption of the drug "Gistak".

Removal of the drug from the body is carried out by the kidneys. A small part stands out as exchange products, it is about 8%. About 40% is excreted in the urine if the drug is taken orally, and 70% if parenteral. The rest is excreted.

It is worth noting that with regular administration of the drug in the prescribed dosage for 4-6 weeks, ulceration takes place. And taking a maintenance dosage overnight reduces relapse of the disease.

Who is prescribed the drug "Gistak"

Instructions for use indicate the diseases and conditions under which the drug is prescribed for treatment and prevention:

• Ulcerous lesions of various parts of the gastrointestinal tract.
• Ulcers that occurred during the postoperative period.
• For the treatment of reflux-esophagitis and alleviation of the symptoms of the disease.
• Gastroesophageal reflux.
• Zollinger-Ellison syndrome.
• Pain epigastric or retrosternal.
• Bleeding in the stomach and intestines.
• Peptic, bleeding ulcers and repeated bleeding.

Also, the medication is used before anesthesia for patients who have a high risk of ejection of acidic stomach contents.

Can everyone take "Gistak"? Instruction for use contains data on contraindications. Let us consider them below.

Who should not take the "Gistak"

Before you start using any medicine, you need to study the annotation. This applies to the drug " Gistak". Instructions for the use of contraindications indicate the following:

• Hypersensitivity to any ingredient of the drug.
• It is not allowed to take medicine for children under the age of twelve.
• With great caution appoint a remedy for patients with cirrhosis of the liver and kidney failure.

Drug therapy during pregnancy and lactation

When studying the active substance ranitidine was found that it is able to penetrate the placenta. In pregnancy for therapeutic purposes, the administration of the drug did not adversely affect labor and fetal development. Use of the drug "Gistak" for pregnant women is possible, but if the necessary benefit will exceed the potential risk to the fetus.

Also, the drug is able to act (albeit in small amounts) in breast milk. For the duration of treatment, Gistakom recommends that you refrain from breastfeeding.

To make it is possible the following conclusion: to prescribe the drug "Gistak" pregnant and lactating it is possible only in case of emergency.

Dosage and form of the drug

The drug "Gistak" is available in the form of tablets. They are white, slightly convex, covered with a sheath, marked on one side by HISTAC 150, on the other side by RANBAXY. One tablet contains ranitidine hydrochloride 150 mg.

In order that the drug does not harm the health, it must be studied before taking the "Histak" instructions for use. Dosage of the drug is prescribed by a doctor, and it can not be exceeded.

Tablets are given to adults in the following dosage: 150 mg in the morning and in the evening. In the presence of ulcers of the duodenum, one-time application before bedtime is 300 mg.

The course of treatment of peptic ulcer is usually about 4 weeks. If no improvement occurs, then a repeat of the course is prescribed.

When relapsing peptic ulcer, the drug is prescribed as a prophylactic agent after the passed treatment, as indicated by the drug "Gistak" instructions for use. Tablets should be taken once a day, at bedtime, in an amount of 150 mg. Preventive dose during the seasonal exacerbation of gastric diseases is also 150 mg per day.

Reflux-esophagitis and erosive esophagitis often require a dosage increase of up to 150 mg four times a day. Treatment lasts up to two months.

The Zollinger-Ellison syndrome also requires an increased dosage of 150 mg 3 times a day. If necessary, the dose can be increased. Studies have shown that patients taking 6 g of the drug per day (the maximum allowable dose) tolerated it well.

Before the anesthesia is to be administered, in order to prevent Mendelssohn's syndrome, take "Histak" - 150 mg the day before the surgery, in the evening, and two hours before the operation.

Children can take the drug from the age of 12, with the dosage taking into account the body weight:

• Peptic ulcer - 4 to 8 mg per kilogram of body weight per day.
• Gastroesophageal reflux - from 5 to 10 mg per kilogram of body weight per day.

In the presence of pathologies in the work of the kidneys, the recommended dose is 150 mg per day.

Side effects of the drug

It is necessary to know what can be undesirable phenomena when taking the drug "Gistak". Instructions for use of the side effects of the drug describes the following:

• Leukopenia, agranulocytosis, recurrent thrombocytopenia.
• Allergic reactions.
• Drowsiness, irritability, increased fatigue, tinnitus.
• Headache.
• Vasculitis, bradycardia, asystole.
• Diarrhea, constipation, dry mouth.
• Reversible hepatitis.
• Skin rashes.
• Acute nephritis, myalgia, discomfort in the mammary glands.

It should be noted that most often the drug is very well tolerated by patients. In case of appearance of side effects of the drug, it is necessary to reduce the dosage or reject the medication, and the body's functions will be restored.

Overdose of the drug

Do not exceed the recommended dose of the drug "Gistak". Instructions for use (a description of the drug given above) warns of a possible overdose. In this case, there may be an increase in adverse events. It is recommended to call a doctor. As an adjunct to treatment, hemodialysis is recommended.

How "Gistak" interacts with other drugs and alcohol

The drug may reduce or increase its effectiveness, as well as neutralize the effect of certain drugs. It is necessary to be careful, taking together with other preparations "Gistak". Instructions for use indicate some features of the drug interaction:

• The action of "Gistak" does not increase or decrease with the joint use of the following drugs: "Diazepam", "Lidocaine", "Theophylline".
• Prothrombin time was changed by joint treatment with coumarin anticoagulants. It is necessary to control it more carefully.
• The simultaneous use with ranitidine of procainamide and its active metabolite can reduce their excretion. This will entail an increase in this substance in the plasma.
• Increased absorption when combined with Gistakom the following drugs: "Triazolam", "Midazolam", "Glipizid."
• Reduces the absorption of the following drugs: Delavirdine, Ketoconazole, Atazanavir, Gefitinib.
• "Sucralfate" in a dosage exceeding 2 g should be taken at an interval of 2 hours, so as not to reduce the effectiveness of ranitidine.
• Drugs that depress the bone marrow increase the risk of developing neutropenia.

With the joint use of alcohol and "Gistak" the level of alcohol in the blood rises. The effectiveness of the drug is reduced by smoking.

Special instructions for the use of the drug

• When taking the drug "Gistak" should refrain from work that requires increased attention, and management of transport and machinery.
• At the beginning of treatment, it is necessary to examine and exclude stomach cancer, since this drug masks the symptoms. It requires special attention to the prescription of medication for elderly patients and those with impaired renal function.
• In elderly patients with existing diseases, such as diabetes, chronic lung diseases, pneumonia may develop.
• With caution, prescribe the drug to patients with impaired liver function, as "Gistak" is metabolized in this organ.

Analogues of the drug "Gistak"

For some reason or other, some patients are forced to take the drug with an identical composition. Analogues include:

• The Zoran.
• "Ranitidine."
• Zantak.
• Acyloc.
• "Ullan".
• "Ranitidine-Akos."
• Ranitidine-Ferein.
• Ranitidine-Lect.

Before replacing the original with its equivalent, you should consult your doctor.

Reviews about the drug

The drug is often prescribed by doctors for both prevention and treatment of gastric diseases. To achieve the desired therapeutic effect and prevent unwanted reactions before using the drug "Gistak" instructions for use, reviews should be considered. So, patients note that the medicine is not on the expensive list, but it works very effectively.

Many people say that they have got rid of an ulcer with the help of this drug. The results are good, there were no side effects. Always keep this medicine in the medicine cabinet.

Patients use the drug for gastritis therapy and the results are also satisfied. There are almost no side effects. The drug is available. You can take and for the prevention. As a result, the number of relapses of the disease is significantly reduced.

Do not take medications without consulting a doctor. This applies even to the most innocuous, at first glance. Health is the most precious thing a person has, take care of it.