Finasteride medication. Instructions and indications

The drug "Finasteride" promotes inhibition of the enzyme that converts testosterone to dehydrotestosterone, a decrease in its concentration in the blood, and also in prostate tissue. As a result, the stimulating effect on the development of adenoma in the prostate gland is reduced. The drug helps to reduce the size of the enlarged prostate, increases the urine flow. Due to the effect of the drug, symptoms of benign type hypertrophy of the prostate are relieved. To reduce the manifestations of pathology may take several months of taking the drug. The drug is good absorbability, the product penetrates into liquids and tissues, its presence is found in the ejaculate. Bioavailability of the drug is not dependent on eating and is about 80%. The drug is excreted through the intestines and kidneys.

Finasteride. Instructions. Indications

The medication is prescribed for benign prostatic hyperplasia. The drug is effective for reducing the size of the enlarged gland, reducing the symptoms of hyperplasia, increasing urine flow. The drug is prescribed to reduce the development of acute retention of urination, requiring surgery (prostatectomy or transurethral resection) or catheterization.

Finasteride. Instructions for use

A day is recommended for five milligrams. On the day the drug is taken once. Therapy is prescribed for an extended period.

Finasteride. Instructions. Adverse Reactions

On the basis of treatment, negative manifestations are relatively infrequent. The drug can provoke gynecomastia, angioedema, decreased libido, skin rash. In some cases, impotence is noted, a decrease in the amount of ejaculate.

Finasteride medication. Instructions. Contraindications

The remedy is not assigned to children and women. The drug is contraindicated in men who have hypersensitivity to the components, prostate cancer, obstructive uropathy. Before and during therapy, it is mandatory to perform rectal examination and other diagnoses by other methods for the presence of prostate cancer. Women during pregnancy and at reproductive age are recommended to avoid contact with the medicine, because the drug has a teratogenic effect.

additional information

Caution in prescribing the drug "Finasteride" (reviews of experts confirm this) should be observed with patients with renal insufficiency. Against the background of a large volume of residual urine or a sharply reduced current, the probability of obstructive uropathy should be considered. In practice, no significant interaction of the Finasteride with the drugs "Vafarin", "Theophylline", "Gliburid", "Digoxin", "Propanolol", "Antipyrine". There is no significant effect of the drug on the cytochrome P450 system. In this connection, the effect of the drug on the pharmacokinetic parameters of drugs passing through the metabolism in the liver cells is not observed. Before using Finasteride, a specialist should warn the patient about the need for long-term treatment.