Embryo embryo in IVF: how does it happen?

Modern life dictates dynamic development, and the flourishing of industry invariably entails losses in the natural balance of man and nature. Increasingly, situations arise where a married couple can not conceive a baby only through joint efforts. Sometimes the verdict is a diagnosis of one of the spouses, but even the absolute health of the partners does not guarantee that the union will be rewarded by the long-awaited child.

In what cases is IVF shown

In vitro fertilization (IVF) is appointed no earlier than the conducted examinations confirm the impossibility of conception. Attempts to treat infertility are often delayed for many years, but the unproductive duration of the process can only reduce the likelihood of a favorable outcome. Seeing the ineffectiveness of the measures taken, the couple has the right to insist on the IVF procedure two years from the beginning of treatment.

How the embryo develops

After fertilization, the egg is placed in a comfortable liquid medium, approximated by the characteristics of the natural maternal. The transformation of an ordinary egg into a zygote, that is, a unicellular embryo, does not yet make the process complete. Before the embryo is attached to the IVF, there must be a repeated division of the cell under the constant control of the embryologist, marking each new stage in the development of the organism.

Starting from the second day from the fertilization of the cell, the doctor can already give an account of the embryo's compliance with the parameters of the norm. Sometimes, if it is weak, but viable, it is allowed to grow in an artificial environment before blastocyst formation (this occurs on the 6th day), and only then it is injected into the uterine cavity. Such reinsurance is justified by reducing the risk to the mother, as it excludes the formation of several fetuses in the womb, and thus minimizes the burden on the body.

With normal cell division, the allowable embryo endurance period is three days. After that, part of them, but no more than two, is transferred to the patient's body, and the strongest specimens from the remaining ones are frozen in liquid nitrogen. But how is the embryo replenishment with IVF?

Preparing a woman for the embryo replanting procedure

Already the very decision to become a mother a difficult way to embryo an embryo with IVF is a sufficient reason for a woman to revise the diet and the regime of the day. It is from the healthy immunity and the strong nervous system of the future mother that the success of the procedure depends.

A few weeks before the date of extraction of the egg, a protein is shown to the woman with a minimal amount of fat and a complete exclusion from the menu of sweet flour, as well as containing soy protein and genetically modified elements of dishes. It is recommended to drink more pure water, natural fresh without artificial additives. Of fruits, it is better to give preference to fresh pineapple (if there is no allergy).

Immediately on the day of embryo insertion into the uterus during IVF it is desirable to stimulate blood circulation in the pelvic organs, for which the doctors advise the spouses to have sexual intercourse and only then, after the woman performs hygiene procedures, get ready for implantation.

Two hours before the scheduled time of injecting a woman needs to drink a pill Piroxicam. Going to ECO, it is better to calm down, remember that the embryo embryo embryo technology is painless and not traumatic.

Embryo Embryo Transfer Procedure

The woman does not see how the embryo is preparing for the transfer, so it may not know that before embryo the embryo envelope is deliberately damaged to facilitate the exit of the egg. The procedure is called "hatching" and it is mandatory.

So, how is the embryo replenishment with IVF? After a conversation with a doctor, a woman takes a comfortable position on the gynecological chair. At the same time, it is better for her to relax and close her eyes, and not to worry, watching how embryos are replenished. With IVF, the readiness of the patient to keep calm is very important. The catheter, which the doctor enters into the cervix, guided by ultrasound observation, does not cause serious discomfort if the pelvic muscles are relaxed and immobile.

Judging by the numerous female reviews, embryo transfer during IVF passes, as it was indicated in the preliminary interviews: painless and in the atmosphere of careful attitude of the personnel. After withdrawal of the catheter, the patient is asked to lie down on the couch on his back and in this position to spend a little less than an hour. During this time, the embryologist will examine viable embryos remaining in the catheter tube and, if the patient agrees, will send them to cryogenic freezing.

What is cryopreservation

Having received the preliminary consent of the couple, from the number of fertilized cells, only strong and hardy specimens are selected, those that can survive under the stress conditions of subsequent defrosting. The more embryos undergo cryopreservation, the more chances a woman will have to resume IVF during the next attempts that may occur years later.

Frozen germ cells occur at extremely low mercury column values, strictly -196 ^° C. Since the procedure for processing with liquid nitrogen and subsequent embryo rehabilitation is a kind of hard hardening in conditions of irreconcilable struggle for life, it is not uncommon to replant embryos with IVF using thawed cells more successfully for woman.

Adaptation after replanting

Since the moment when the woman leaves the medical room, for her the most important in the next three days is the rest. The regime after IVF embryo insertion for 72 hours provides for practical immobilization of the patient. Even with a rare rise in the toilet room, physical support of the husband is desirable in order to minimize the inflow of blood to the pelvis. Water procedures on the first day are contraindicated!

Beforehand, a diet is stipulated with a doctor, but if a woman is healthy and has no special requirements, then after embryo transfer with IVF one can eat everything that was before, but with an emphasis on natural products, and, of course, without including in the diet of coffee, fatty or large quantities Flour food.

After three days of the recumbent regime, a stage of moderate activity begins. Without sudden movements, a woman can carefully perform simple domestic activities, walk on the street, avoiding any emotions. At this stage it is important to drink a lot of pure non-carbonated water.

Control

In the first days after embryo transfer, a woman often encounters a problem of fever, but if you recall the essence of the performed intervention in the body, the immune system response will become clear. Lower the thermometer should not be, if the mercury column does not rise above 37.6 ⁰ . It is necessary to give the body its own "assimilate" new information and come to terms with the fact. In the nearest visit to the doctor, this phenomenon is recorded and analyzed.

It is necessary to pay attention to the prescribed injections. The total number of drugs will be three (with the standard prescription): two injections of "Utrozhestan" on the night after the procedure, one injection of Progesterone for the morning and only five injections (according to the prescribed scheme) of "Fragmina" responsible for the normal circulation of blood in the pelvic organs. "Fragmin" can be excluded from this list if, according to the results of the coagulogram, the coagulability of the patient's blood does not deviate from the norm.

Behavior of the body as a consequence of the IVF procedure

The panic of women, when they encounter phenomena after the puncture, which seem to them incomprehensible, is caused by a low informative value. Below is a list of such phenomena, as well as options for a correct reaction to them:

• Drawing, obsessive pain in the lower abdomen after the procedure, as in menstruation, is the absolute norm. Take nothing extra.
• Vaginal discharge in the form of a pinkish liquid on the 6th to 12th day after embryo transfer is an expected and desired phenomenon, which says that the implant is fixed on the uterine wall. Normally, if bleeding of this kind lasts no more than 4 hours. The doctor should be informed of the situation and conduct an examination to properly assess the patient's condition.
• Abundant bleeding or discharge of dense color signals an unsuccessful replanting and the need for urgent hospitalization. In rare cases, urgently taken measures save pregnancy.

Exactly two weeks after the puncture, a test is carried out for human chorionic gonadotropin (HCG). Results are given on the same day, and a woman can congratulate herself if the concentration of this important hormone is increased. Sometimes a test for HCG requires a recurrence after 72 hours; Such control is due to the presence of a weakly expressed concentration.

Seven days after blood donation to the hormone (with a positive response), an ultrasound is performed to ascertain the onset of pregnancy. In another 14 days, the second is assigned to evaluate the development of the fetus.

In the case of negative HCH, the administration of drugs to maintain the result of IVF is stopped.

Critical days, which should go on the 5th-7th day, serve as a definite indicator of a failed attempt at replanting.

What can affect the outcome of the replanting

A frequent factor complicating the attachment of the embryo to the wall of the uterus is myoma. Embryo 1 embryo IVF in this situation is carried out in such a way that the zygote is not near the tumor, which has the property to expand. Other important conditions for the favorable survival of the embryo in the maternal body are the right timing (usually on the 20th day of the cycle) and the optimal maturity of the fertilized cell. If the doctors set other deadlines, you should take it calmly, because the body does not always work with the accuracy of the clock, and the nuances that take into account the individuality of the woman are able to determine a good outcome.

But even in the case of a negative test, you should not consider that the joy of motherhood is not for you - the real percentage of luck after the first attempt rarely exceeds 45%. It may be necessary to slightly change the diet or abandon bad habits, if it was not done earlier, and definitely try again, using the embryonic cells after cryopreservation.