Analogues of "Clotrimazole": a description of the drug, instructions, contraindications and reviews

"Clotrimazole" is an antifungal drug. The drug has antibacterial, anti-amebic and antitrichomonadnym action. The active component destroys the cell membranes, resulting in pathogenic microorganisms perishing. The spectrum of action of this tool is wide enough. The drug "Klotrimazol" is able to eliminate the pathogens of virtually all diseases of bacterial and fungal etiology. The medication is suitable both for self-administration and for use in the complex, it is also used for preventive purposes. If necessary, you can choose the analogues of "Clotrimazole".

Composition, form of release

There are several dosage forms. The drug is made in the form of vaginal suppositories and tablets. The means for external use - gel, cream, ointment, solution with active substance concentration of clotrimazole 1% are produced. Candles and tablets contain 100 mg of the main component, the tablets can contain 500 mg of clotrimazole.

Of the auxiliary substances in the composition there are nipagin, tween-80. Helps glycerol, petroleum jelly. Additionally, cetyl alcohol is used , distilled water.

Pharmacodynamics

"Clotrimazole" acts by inhibiting the synthesis of ergosterol, necessary for the formation of a membrane of cells of microorganisms. As a result, its permeability deteriorates, cell lysis occurs. This drug and "Clotrimazole" analogs contribute to an improved permeability of the phospholipid coat, which liposomes possess, and vacuolization of the cytoplasm. In addition, the number of ribosomes decreases. The drug inhibits the activity of peroxidases, which affects the process of destruction of cells of pathogenic microorganisms. In cells, hydrogen peroxide is better accumulated, so the causative agents of the disease are destroyed more efficiently.

Using "Clotrimazole", you can cure erythrasma and diseases caused by trichomonads, staphylococci, yeasts, dermatophytes.

Pharmacokinetics

Absorption of the drug is insignificant and corresponds to 3-10% of the used dose. The drug penetrates into the body through the mucous membranes and skin.

Indications

Consider cases when it allows you to assign "Clotrimazole" instructions for use. Analogues can be used to treat the same diseases. The drug is indicated for the detection of such diseases:

• Mycosis, the course of which is complicated by secondary pyoderma;
• Erythrasma;
• Deprive the pitybeard;
• Candidiasis superficial, the causative agents of which are fungi, dermatophytes and microorganisms that exhibit sensitivity to clotrimazole;
• Mycoses, in which the feet are affected, the folds of the skin;
• Fungal diseases of the skin.

"Clotrimazole" (ointment), analogues of this form of the drug is used to treat fungal infections, the development of which was provoked by fungi mold, blastomycetes and dermatomycetes. Ointment is treated with dermatomycosis, to which a secondary infection has joined.

Contraindications

With the use of this drug, no treatment for diseases that developed in women during the first trimester of pregnancy. Contraindication to the use of the drug is hypersensitivity to its components. Regarding the treatment of "Clotrimazole" during menstruation - in this period it does not produce. You can use the medicine for breastfeeding, but with caution.

Application of the drug, dosing

"Clotrimazole" (cream), analogs are used on affected areas, which were previously cleaned and dried. The agent is applied to the skin thinly, then gently rubbed. The procedure should be performed two or three times a day. To cleanse the skin, it is recommended to use soap, the pH of which is neutral. The duration of therapy is determined by the severity of the condition, the localization of the lesion, the effectiveness of treatment.

Usually, for elimination of dermatomycosis it takes at least a month, pityriasis can be eliminated in 1-3 weeks. Fungal leg injuries are treated even after the disappearance of signs that accompanied the disease, in addition, you need to lubricate the skin for at least a half-month.

"Clotrimazole" is a tablet, analogues are used for six days. In the evening of each day, one tablet of the drug is placed deep into the vagina. If there is such a need, in the morning they introduce one more. The term of treatment can be increased to twelve days. The most effective option - the simultaneous use of ointments and tablets. It is possible to repeat the course of treatment after his appointment as a doctor. For easier administration of the pill, you should lie on your back or bend your knees slightly.

Candidiasis balanitis and vulvitis are treated with cream, applying it to the affected areas daily for two or three times. The duration of the course is at least six days, usually not more than twelve.

"Clotrimazole" is candles, analogues are prescribed for both women and girls. Their use is possible after starting the sexual life. Candles are placed deep into the vagina in the evening. For easy administration, you can lie on your back or bend your legs. Six days must be treated. Continue therapy only after receiving the appropriate doctor's advice.

Preparations in the form of gel, ointment, cream are applied in a small layer, gently rubbed. The procedure is repeated several times a day (2 or 3). The skin should be cleaned with a neutral pH and dried.

Like medications of other forms, the solution is also applied in a thin layer in the morning and evening, it is well rubbed. It is necessary to use several drops of the drug. The solution is suitable for the treatment of adult patients and children. It is necessary to treat both the affected area and the areas adjacent to it. After acute symptoms have disappeared, treatment is still about a month.

If the feet are affected by dermatomycosis, the medicine after the elimination of symptoms is used for another half a month. Use the solution after each procedure of washing the feet.

Adverse events

The original preparation, analogues of "Clotrimazole" can cause side effects. Rarely, there is swelling, blisters in the areas of application, skin peeling and irritation occur. There may be hives, burning, itching, it is possible the development of erythema.

special instructions

The possibility of prescribing a pregnant or lactating woman should be determined by the doctor taking into account many factors.

If the patient has liver problems - liver failure, it is necessary to regularly check its function.

When using the drug, avoid applying it to areas near the eyes.

The drug can be used to treat onychomycosis with short-cut nails, so the drug will penetrate better into the affected area. In such cases it is better to use the solution, it provides better penetration.

The appearance of hypersensitivity to the drug is an excuse to cancel the drug. Lack of the desired effect within a month requires confirmation of the diagnosis.

In order not to re-infection, the implementation of therapy is shown to both a woman and a man. To effectively eliminate trichomoniasis, combined treatment is necessary in combination with drugs that have systemic effects.

If necessary, combine the drug with other drugs you need to consult a doctor and follow his recommendations.

The cost of the drug, reviews, analogues

If you want to replace "Clotrimazole", analogues and prices for them will help to make the right choice. The same active substance contains "Faktodin", "Lotrimin", "Guinea-Lotrimin". Analogues in structure belong to Kanesten, Antifungol, Klotrimazol-Akri. The same active substance has in its composition "Yenamazol", "Amicon". On clotrimazole, the action of the preparations "Kanison" and "Imidil" is based. As a substitute, the doctor can appoint "Kandizol", "Kandibene". Possible treatment with the use of "Candida".

A solution (15 ml) can be purchased for 120-140 rubles, ointment (20 g) - for 36-89 rubles, gel (20 g) - for about 23 rubles, cream (20 g) - for 37-155 rubles . The cost of tablets (6 pieces of 100 mg) is 15-55 rubles.

The original drug, Clotrimazole analogs, does not help everyone, sometimes there are side effects such as burning, itching. Some women are noted to have bloody discharge. Many people like the price, in most cases the drug is effective, and in treatment with its use, there are no unpleasant sensations. For the most effective treatment, use the drug only after the appointment of a doctor and in accordance with its recommendations.