"Zinnat": analogues. Preparation "Zinnat": reviews, price

At what deviations can doctors prescribe a medicine "Zinnat"? Analogs of this drug, its pharmacological properties and instructions for use will be presented below. Also we will tell you about whether this medication has contraindications and side effects, in what forms it goes on sale, what composition and properties it has, what its cost and so on.

Forms of release of a medicament and their composition

In what form can you find a drug Zinnat in the pharmacy? Analogues of it are made in different forms. As for the very mentioned preparation, it can be purchased in the form of tablets and granules for the preparation of a suspension. Let's consider the composition of these variants of medicines in more detail:

• Pills "Zinnat". The instruction, attached to the preparation, states that all tablets are covered with a special coating. This medicine contains an active element, such as cefuroxime. In addition, the medicine "Zinnat" (125 and 250 mg) includes some auxiliary components. These are: hydrogenated vegetable oil, croscarmellose sodium, silicon dioxide colloid, microcrystalline cellulose, dangerous white, sodium lauryl sulfate, propylene glycol, propyl parahydroxybenzoate and methylhydroxypropylcellulose, methyl parahydroxybenzoate. In a cardboard package of a medicinal product there may be 5 or 10 tablets.
• Medication "Zinnat" (suspension). These are pellets designed to prepare a sweet suspension for the treatment of young children and adolescents. The solution should be taken only inside. As in tablets, the active substance of this form of the drug is cefuroxime. Also, the medicinal granules "Zinnat" (125 and 250 mg) contain auxiliary components. It is potassium acesulfame, sucrose, purified water, povidone K30, stearic acid, aspartame, xanthan gum and flavored baby "Tutti-frutti". In the sale of the drug "Zinnat" in granules comes
  In a bottle of dark glass in a volume of 50 ml. Also for more convenient use, the kit includes a dosage spoon and a measuring cup.

It should be particularly noted that some pharmacological companies produce and powder "Zinnat", intended for intravenous and intramuscular injection.

Pharmacological properties of medicament

What are the pharmacological characteristics of the drug "Zinnat" (250 and 150 mg)? The drug is a second generation cephalosporin antibiotic for oral administration. It acts bactericidal, disrupting the synthesis of bacterial cell walls. The drug has a fairly broad spectrum of action. One can not help saying that it is resistant to the effects of many beta-lactamases.

The effectiveness of the drug against infections and bacteria

With respect to which bacteria is the most effective medication "Zinnat" (250 and 150 mg)? As a rule, it is very often prescribed against such gram-positive aerobic bacteria as golden and epidermal staphylococci (including strains that are resistant to penicillins and with the rare exception of methicillin-resistant strains). Also, the drug is highly effective in pyrrolidonyl peptidase, pneumococcus, group B streptococcus and whooping cough.

In addition, the drug is often prescribed for the control of aerobic Gram-negative bacteria (Escherichia coli, Klebsiella SPP., Providence SPP., Haemophilus influenzae and Ampicillin-resistant strains).

One can not help saying that Zinnat is very effective against gonococci (strains producing and not producing penicillinase), meningococcus, salmonella and so on.

In addition, it should be noted that the active substance - cefuroxime - is resistant to methicillin-resistant strains of golden and epidermal staphylococcus, Campylobacter SPP., Pseudomonas spp., Listeria, etc.

According to the research of specialists, when the active ingredient of the preparation is combined with antibiotics belonging to the group of aminoglycosides, the patients can have an additive effect, and sometimes synergism.

Indications for use of the medicinal product

In what cases is the antibiotic "Zinnat" prescribed? The price of the drug in different forms is presented below. According to the instructions of the medication, it should be taken in the presence of such pathologies as:

• ENT-infection. The drug is prescribed for tonsillitis (inflammation of the tonsils), pharyngitis (inflammation of the pharynx), acute middle otitis (inflammation of the middle ear) and sinusitis (inflammation of the paranasal sinuses).
• Infections of the lower and upper respiratory tract. The drug "Zinnat" with angina helps very well. However, it is often prescribed and in the presence of other diseases. These include postoperative infection of the chest, lung abscess (or accumulation of pus in the lung tissue), infected bronchiectasis (that is, an expansion of the part of the bronchus that is irreversible), bacterial pneumonia and chronic / acute bronchitis.
• Granules and tablets "Zinnat", the instructions for use of which contain complete information on the method of taking the medication, can be prescribed by a doctor for diseases of soft tissues and skin. These diseases include the following pathological conditions: phlegmon (or purulent inflammation of the cellulose), erysipeloid (i.e., infectious lesions of the skin), furunculosis with the formation of a number of boils, wound infection, in which pathogens rapidly multiply pathogenic microorganisms, impetigo (i.e., the formation of pustules , Which were caused by strepto- and staphylococci), erysipelas (severe inflammation of the skin caused by streptococcus), pyoderma (skin diseases that were provoked by pyogenic microorganisms Isms).
• Infections of the genitourinary system. Medication Zinnat, analogues of this drug (if necessary, replacement of the described agent) can be prescribed for acute or chronic pyelonephritis (inflammation of the kidneys), urethritis (inflammation of the walls of the urethra), cystitis (inflammation of the bladder), asymptomatic bacteriuria (colonization by bacteria of the urinary Ways), gonorrhea (an infectious disease that is caused by gonococcus).
• Infections of the pelvic organs. The drug well cures cervicitis (i.e. inflammation of the cervix), endometritis (or inflammation of the mucous uterus), and adnexitis (inflammatory processes in the appendages of the uterus).
• Diseases of joints and bones. As you zilili, the application of "Zinnat" is quite extensive. It can be used not only to treat internal organs and skin diseases, but also bones. So, it is often prescribed to patients with septic arthritis (with the penetration of bacteria into the joint cavity) and osteomyelitis (with purulent inflammation of the periosteum).
• Also, the drug is very effective in meningitis (inflammation of the membranes of the brain and spinal cord), Lyme disease (transmitted through tick bites) and sepsis (that is, an infectious disease caused by the ingestion of bacteria, unicellular fungi or toxins into the blood).

Among other things, with the help of the medicine "Zinnat" is carried out and prevention of complications during operations on the chest, abdominal organs, pelvis and joints.

According to reviews of patients and specialists, this drug is very effective for all of the above pathologies. But this is only if they were caused by bacteria that are sensitive to the drug. If no effect of the drug is observed, then you should see a doctor and take a medical examination again.

Contraindications to the use of the medicinal product

The drug "Zinnat", a photo of which is presented in this article, is not recommended for allergic reactions of the patient to penicillins, hypersensitivity to the active substance (cefuroxime), as well as diseases and bleeding of the digestive system. Do not give it to children up to three months.

It should also be noted that the drug should be taken with extreme caution by pregnant women (especially in the first trimester) and during breastfeeding.

Zinnat remedy: instructions for use, price

After the appointment of the drug, the doctor must explain to his patient how exactly this medication should be used. Also, before you start receiving it is recommended to read the attached instructions.

Tablets "Zinnat" should be taken during or immediately after consumption of food. With angina and other diseases, the drug is recommended to be used for 5-10 days. With Lyme disease, the duration of the therapy should be at least 20 days.

In most cases, the medicine "Zinnat" with angina and other infectious diseases is prescribed to adults in the amount of 250 mg twice a day. In pyelonephritis, the antibiotic is used with the same frequency, but in an amount of 125 mg.

If you suspect a pneumonia, as well as Lyme disease, with severe infections of the respiratory tract, taking the drug in a single dose should not be 250, but 500 mg. In this case, the periodicity is doubled. With gonorrhea (uncomplicated), the medication should be taken once a day in the amount of 1 g.

The drug "Zinnat" (suspension for children): instruction on the use of medicament

In the event that treatment with this drug was prescribed to a child, doctors recommend using granules intended for the preparation of a sweet suspension. It should be noted that 10 ml of liquid preparation correspond to 250 mg of active substance (cefuroxime).

In what dosage is the Zinnat (suspension) medication prescribed for children? Instruction to this tool states that an adolescent over 12 years of age is prescribed twice a day for 125 mg.

For children from three months to 12 years, a single dosage is calculated by multiplying 10 mg per kilogram of the child's weight. The frequency of admission for toddlers remains the same as for adolescents.

In case of severe infectious diseases and an average otitis, a drug of 250 mg twice a day can be given to a teenager over 12 years old, and a child can receive 15 mg / kg at a similar multiplicity from three months.

Injectable form of the preparation: instructions for use

Now you know how the drug "Zinnat" (suspension) is given to a child. However, it should be noted that, in addition to granules and tablets, this medication is also available as a powder for injections.

With intramuscular and intravenous administration to adults, an antibiotic is administered three times a day, 750 mg daily. If the patient has more severe forms of the disease, then once-a-day dosage is doubled.

Children can also be injected with Zinnat. In this case, it is administered three times a day. In this case, the dosage is calculated by multiplying: 60 mg of active substance x per kilogram of the weight of the adolescent.

At clinical indications it is possible to switch from parenteral use of antibiotic to suspension or tablets.

Side effects after taking medication

Are there any side effects after taking Zinnat? The answer to this question is contained in the medication instructions.

So, the following negative phenomena can be attributed to side effects after application of the mentioned agent:

• Fever, hives and itching (manifested on the skin), skin rash and the development of anaphylaxis;
• Hypoprothrombinemia, leukopenia, hemolytic anemia, thrombocytopenia and eosinophilia;
• Hearing impairment, convulsions, headaches and drowsiness;
• Diarrhea, increased activity of liver enzymes, vomiting, hepatitis, nausea and cholestatic jaundice;
• Vaginosis, dysbacteriosis and interstitial nephritis.

It should also be noted that in the responses to patients about the medication very often there is information that after taking the drug some women have thrush. The appearance of such a deviation is due to the large growth of the Candida group fungi during the period of antibiotic therapy.

Special instructions on the use of the medicinal product

If the drug has been used for a long time, then the patients may experience increased multiplication of resistant microorganisms. As a rule, this requires an immediate cessation of treatment.

It is not a secret to anyone that taking anabiotic drugs very often leads to the appearance of diarrhea. And the "Zinnat" medication is no exception. Thus, patients taking this remedy should bear in mind that against this background they may develop pseudomembranous colitis.

As shown by therapeutic practice, during the treatment of Lyme disease antibiotics in patients may be noted Yarisch-Gerxheimer's reaction. According to experts, it is a consequence of the bactericidal effect of the drug on the pathogen - spirochete Borrelia burgdorferi. In order for the patient not to stop taking the medication spontaneously, the doctor must explain to him that this is a fairly common and frequent consequence of treating Lyme disease with antibiotics. After a certain period of time, it passes by itself.

If the drug "Zinnat" was prescribed to patients diagnosed with "diabetes mellitus," it should be taken into account that sucrose is included in the suspension. In this case, it is recommended to replace the mentioned form of the drug with another one. For example, tablets or powders may be used to prepare a solution for intravenous or intramuscular injection.

If, in order to treat a disease, a small child or adolescent was prescribed a drug in the form of a suspension, you should know that it is necessary to prepare it using a warm rather than a hot liquid.

Interaction with other medical devices

Can I simultaneously take Zinnat with other drugs? In most cases, yes. But at the same time, several factors should be taken into account. For example, concomitant administration of the drug cefuroxime and a drug such as Probenecid can lead to an increase in the AUC of the former by 50%.

It should also be noted that with the simultaneous use of antibiotic and antacids, the bioavailability of the former decreases. But this applies only to the preparation in the form of a suspension.

Price and analogues of an antibiotic

How much is the medicine "Zinnat"? The price of this product in different pharmacy chains may vary. However, the average cost of medication in tablets is about 400 Russian rubles (for 10 pieces). As for the suspension, then for 50 ml of the drug you need to give about 350 rubles. A similar price has been set for powder for injections.

What should I do if, for one reason or another, the patient was unable to purchase the Zinnat drug? Analogues of it are always sold in pharmacy chains. If you do not know what these preparations are, then we will list them right now.

So, the analogues of the "Zinnat" agent for the active substance are the following medicines:

• "Supero".
• Aksetin.
• "Cephus".
• "Axosafe."
• "Cefuroxime axetil".
• "Antibioksim."
• "Cefuroxime sodium."
• "Aszenoveris."
• "Cefuroxime Cubi."
• "Zinatsef".
• "Cefuroxime."
• Zinoximor.
• "Cefurozine."
• Ketoceph.
• "Cefurabol".
• "Kefstar."
• "Cefroxim J."
• "Ksorim".
• Cetil Lupine.
• Proxim.

It is impossible not to say that all mentioned preparations have different forms of release. In this regard, they can be used as adults, and adolescents and young children.

Shelf life of the preparation and its storage conditions

The shelf life of Zinnat tablets is 2 years from the date of manufacture, and suspensions and powder for injections are 12 months. But this is only if the storage of the drug was carried out exclusively at room temperature. By the way, it is desirable to place the already prepared suspension in a refrigerating chamber. Keep it in this form should not more than ten days. At the end of this time, it is strictly prohibited to use the medicinal product.