What are the pricks for psoriasis?

Psoriasis is one of the skin diseases. Getting rid of him is a rather problematic process that can take years, and sometimes even all his life. Despite the fact that psoriasis poses no danger to others, it looks not at all aesthetically pleasing and can disgust.

For treatment, special creams, ointments and other topical preparations are usually used. In search of a more effective remedy, psoriatic injections were developed. It is about them that will be discussed in the article.

How is psoriasis manifested?

The appearance of the disease is associated with malfunctions in the life cycle of skin cells. At a time when in a healthy body this period is approximately 30 days, during psoriasis it decreases to 4-5 days.

In the affected areas, inflammation of the skin is observed , which is accompanied by the appearance of red plaques. They look like dry spots, raised above the surface of the body. Very often, the whole process is accompanied by a strong continuous itching and flaking.

Means for treatment of psoriasis

As already mentioned above, pharmaceutical companies for the control of psoriasis usually produce drugs of local type of action (creams, ointments, sprays) and tablets. Unfortunately, all of them differ only in short-term effectiveness. That's why new methods for fighting the disease began to be developed, which if they can not completely rid of it, then they will maximize the period of remission. One such means are injections for the treatment of psoriasis.

What are the advantages of injections?

In comparison with other drugs (tablets, creams, and so on), injections have several important advantages.

First, a very rapid onset of action of the drug.

Secondly, the treatment of psoriasis with injections involves the direct injection of the drug into the blood. And this means that he will not need to go through the aggressive environment of the stomach, as in the case of tablets.

And finally, thirdly, psoriasis shots have a stronger and lasting effect.

With all this, the most optimal option is to inject the medicine directly into the area affected by the plaques.

Types of pricks from psoriasis

The psoriasis shots can be divided into several groups depending on the composition and type of exposure.

1. Immunosuppressive drugs. They are presented by such drugs as "Remicade", "Humira" or "Stelara".
2. Immunomodulators. These include "Pyrogenal" and "Glutoxim".
3. Hepatoprotectors. As an example, you can name "Heptor" and "Heptral".
4. Glucocorticosteroids. This is "Flosteron" and "Diprospan".

Let's take a look at some of the above mentioned tools in order to understand how the psoriatic shots work.

"Diprospan"

The active substance of the drug is betamethasone.

"Diprospan", whose price is not too high, has immunosuppressive, anti-shock, anti-allergic, anti-inflammatory, desensitizing effect.

The drug has become quite popular due to the possibility of inhibiting the synthesis of substances that cause the appearance of an inflammatory reaction, already at the cellular level.

Diprospan is available as a suspension for injection or solution. In this case, depending on the indications, the drug can be administered intramuscularly, intradermally, perarticularly (around the joint) or intra-articularly.

The required dose depends on the mode of administration and the site for injection.

"Diprospan", as a rule, does not cause significant negative reactions of the body in case of its one-time use or a short course of treatment. Nevertheless, the manufacturer in the instructions for use warns the patient about the possible development of the following side effects:

• Hypernatremia, fluid retention in tissues, increased excretion of potassium and calcium from the body, weight gain
• Heart failure, increased blood pressure;
• Metabolic disorders in the muscle tissue, thinning of bone tissue, fractures of tubular bones, aseptic necrosis of the head of the femoral and humerus bone;
• Flatulence, hiccough, pancreatitis, erosive-ulcerative lesions of the digestive system;
• Increased sweating, dermatitis, atrophy and thinning of the skin, impaired wound healing;
• Increased intracranial pressure, convulsions, headaches, dizziness, depression, increased irritability, insomnia;
• Secondary adrenal insufficiency, menstrual irregularities, stunting and sexual development in children, steroid diabetes mellitus;
• Cataract, glaucoma, increased intraocular pressure;
• Anaphylactic reactions, angioedema, aseptic abscesses, cutaneous and subcutaneous atrophy.

Contraindicated the use of "Diprospan" in the presence of hypersensitivity to its constituents and systemic mycoses. With special care should be taken to its use in the presence of ulcerative diseases, cirrhosis, renal failure, chicken pox, osteoporosis, hypertension, thrombophlebitis.

What is the cost of injections of "Diprospan"? The price can range from 173 rubles and above, it all depends on the pharmacy, the region of residence and the number of ampoules in one package.

"Humira"

The active active substance of the drug is adalimumab. It should be noted immediately that the drug "Humira" is quite expensive. The price for it is in the range of 64 000 rubles.

The product is produced in the form of a slightly colored solution in a transparent disposable syringe.

Contraindications to the use of the drug:

• Pregnancy and lactation;
• Age younger than 16 years;
• Presence of infectious diseases;
• Hypersensitivity to the components of the drug.

"Humira" can cause a number of side effects:

• Infectious diseases of the urinary system or respiratory tract;
• Malfunctions in the immune system;
• Confusion, depression, insomnia;
• Headache, dizziness, drowsiness;
• Ringing, stuffiness or pain in the ears;
• Glaucoma, edema of the eyelids, redness of the eyes;
• Tides, tachycardia, hypertension;
• Nasal congestion, coughing, shortness of breath, pulmonary insufficiency;
• Abdominal pain, constipation or diarrhea, nausea, vomiting, hemorrhoids, gastritis, flatulence, colitis;
• General and local allergic reactions;
• The appearance of protein in the urine, increasing the level of creatinine, alkaline phosphatase and urea.

In pharmacies, the drug is dispensed only on prescription. He also picks up the necessary dose of medication.

"Stelara"

The main active substance of the drug is ustekinumab.

The product is available as a solution for injection.

Strokes from psoriasis "Stelara" are not used for treatment in the following cases:

• Pregnancy and lactation;
• Presence of infectious diseases in the acute phase;
• With hypersensitivity to the components of the drug;
• Children under the age of 18;
• In the presence of malignant neoplasms.

Caution should be applied to its use in the presence of a malignant tumor in an anamnesis, chronic or recurrent parasitic or infectious diseases of bacterial, viral or fungal breed, as well as for the treatment of elderly patients.

The most frequent side effects (in 1 case out of 10) are upper respiratory tract infections and nasopharyngitis. A little less often, taking the drug may be accompanied by inflammation of the subcutaneous fat, viral diseases of the nasal cavity or mouth of the pharynx.

In addition, there may be dizziness, nasal congestion, diarrhea, allergic reactions, a state of fatigue.

As the most serious side effects can be identified the appearance of malignant neoplasms. Although the studies conducted to date have not revealed any relationship between the use of the drug and the development of the tumor.

"Pyrogenal"

The active substance of the preparation is a bacterial lipopolysaccharide.

The product is available as a solution for injections or rectal suppositories (suppositories).

"Pyrogenal" has an immunomodulating effect, and also has good anti-inflammatory, adjuvant and desensitizing properties.

The use of the drug is contraindicated in case of hypersensitivity to its components, as well as during pregnancy and lactation, in renal, hepatic or heart failure.

"Pyrogenal" (injections) can cause such side effects as chills, fatigue, fever, nausea, headaches, back pain, fever.

The medication is dispensed only by prescription.

Psoriasis shots: patient feedback

What do the patients themselves say about the above injections? Each drug has its pluses and minuses. But if you combine all that has been said about these remedies, you can draw small conclusions.

First, they do have a very rapid effect on the body and are much more effective than topical preparations.

Secondly, treatment with injections is quite convenient. In addition, when choosing this type of therapy, there is no need to irritate the stomach with the chemical composition of the tablets.

With regard to cons, they are the high cost of some drugs (an example of this can serve as "Humira") and a significant number of possible side effects.

Be healthy!