"Thiocetam": instructions for use and price. Tablets and injections "Thiocetam"

Do you know why doctors prescribe such a tool as "Thiocetam"? Instructions for the use of this tool, as well as its release forms, composition and testimony will be presented in this article. We will tell you about the pharmacological characteristics of the medication, whether it has contraindications and side effects.

Forms of the preparation and its composition

Currently, pharmacies can buy two different forms of medicine "Thiocetam." Instruction for use states that such a product is available in the form of a solution and tablets (for intravenous and intramuscular administration, as well as for oral administration, respectively).

The active substance of the solution is thiotriazoline and piracetam. This form of the drug is sold in ampoules (10 and 5 ml each), which are placed in the cell contour packs and cardboard packs.

As for the tablets, their active substances are also thiotriazoline and piracetam. On sale they come in a cardboard package of 60 pieces.

Pharmacological characteristics

What are the properties of the drug "Thiocetam"? Instructions for use inform you that this product belongs to the group of cerebroactive. It is able to display antioxidant, anti-ischemic and nootropic properties.

The therapeutic effect of the drug is due to the mutual potentiating effect of pyracetam and thiotriazoline. The first element is the cyclic derivative of GABA. This substance is a nootropic remedy. It acts directly on the brain, improving attention and consciousness, learning and memory. In this case, the drug does not have any psycho-stimulating and sedative effects.

At the neuronal level, a substance such as pyracetam significantly facilitates synaptic transmission. It affects the activity and density of postsynaptic receptors. It should be especially noted that the hemorheological properties of pyracetam have a direct relationship with its effect on platelets, erythrocytes and vessel walls.

As for tiotriazoline, it is able to react with lipid radicals and active forms of oxygen. Such a process is due to the pronounced reducing properties of the thiol group.

Also it should be said that tiotriazoline prevents formation of reactive oxygen species. This process is carried out by reactivation of such antiradical enzymes as catalase, superoxide dismutase and glutathione peroxidase.

From all of the above, we can safely conclude that the drug "Thiocetam" (injections and pills) improves cognitive, as well as integrative activity of the brain, promotes learning and eliminates amnesia. In addition, the drug increases the performance of both long-term and short-term memory.

Indications

Why is the "Thiocetam" needed? The instruction for use contains the following indications:

• Cerebral ischemia (chronic);
• Ischemic stroke (recovery period);
• Nondemantic cognitive impairment ;
• Encephalopathy is diabetic.

Contraindications

Is there a contraindication to a medicine like "Thiocetam"? The instruction says that this drug can not be used when:

• Hypersensitivity to thiotriazoline or pyracetam, as well as to other substances of the medical device;
• Hauge Huntington ;
• Severe renal failure of a chronic nature;
• Acute disorders of cerebral circulation (i.e. hemorrhagic stroke) ;
• Psychomotor agitation;
• Pregnancy and lactation;
• Hereditary lactose intolerance, lactase deficiency;
• Deficiency of sugar and fructose intolerance;
• Glucose-galactose malabsorption;
• In childhood.

Admission with caution

In the presence of any deviations, with special care are prescribed a medication such as "Thiocetam"? The instruction says that this drug is able to influence the aggregation of platelets. In this regard, it should be used with caution in patients with surgical interventions, as well as with violation of hemostasis and with severe bleeding.

Also, the use of the medicament in question should be controlled by the doctor in chronic renal failure, in old age, in cardiovascular pathologies (in this group of patients, side reactions are most often noted).

Preparation "Thiocetam": instruction for use (injections)

If it is not possible to take the medicine inside, it is injected intramuscularly or intravenously.

With ischemic stroke (during the recovery period), as well as chronic circulatory disorders in the brain, the drug is prescribed for 20-30 ml. Preliminarily it is diluted in 0.9% solution (100-150 ml) of sodium chloride, and then injected intravenously (drip) once a day.

The course of this treatment should be at least 15 days. After this, they switch to the tablet form of the preparation.

As with diabetic encephalopathy should I use a solution of "Thiocetam"? Instructions for use (injections should be prescribed only by the attending physician) states that in this case the drug should be used in the volume of 5 ml (intramuscularly) once a day for 10 days. After such a course, you can safely switch to the tablet form.

"Thiocetam" medication: instructions for use (tablets)

Tablets should be taken orally for half an hour before meals.

With ischemic stroke (during the recovery period), as well as with chronic circulatory disorders of the brain, the patient is given 2 tablets three times a day. Such treatment is carried out for 25-30 days. If necessary, the course can be extended to 4 months.

For the treatment of diabetic encephalopathy, the patient is also prescribed 2 tablets three times a day. However, in this case, the treatment is carried out for 45 days.

The last dose of the drug should be taken no later than 5 pm. This will prevent sleep disturbance.

Overdose

What are the symptoms when the drug "Thiocetam" is incorrectly taken (the price of the medication is indicated below)? If you do not follow the prescriptions of the doctor, the patient may have increased dose-related side effects. As a treatment, you should cancel the medicine, induce vomiting, rinse the stomach (when taking the pills) and use symptomatic therapy.

Side effects

There are many undesirable effects that can occur after using a medicine such as "Thiocetam." Instructions for use (the price of this drug is quite high) contains the following list of undesirable reactions:

• Nervous system: motor disinhibition, anxiety, irritability, hallucinations, drowsiness, tinnitus, depression, insomnia, headaches, ataxia, dizziness, exacerbation of epilepsy, mental agitation, confusion, asthenia and imbalance.
• The digestive tract: dry mouth, nausea, bloating, vomiting, abdominal pain and diarrhea.
• Heart and blood vessels: hypertension, tachycardia, pain in the heart, arrhythmia, coronary insufficiency (in the elderly).
• Allergy: angioedema, hypersensitivity, dermatitis, anaphylactic reactions, itching, fever, urticaria.
• Respiratory: attacks of dyspnea and shortness of breath.
• Organs of hearing: vertigo.
• Metabolism: weight gain.

Drug Interactions

Injections and tablets "Thiocetam" should not be prescribed with agents that have an acidic pH.

Due to the presence of pyracetam in the preparation, the effect of antianginal drugs and antidepressants is enhanced.

With simultaneous use with thyroid hormones, there is a possibility of confusion, sleep disturbance and irritability.

Metabolic interaction with other drugs is unlikely.

Joint intake of the drug with alcohol does not affect the level of piracetam concentration in the blood.

special instructions

With prolonged treatment of the elderly, continuous monitoring of kidney function is recommended. If necessary, then adjust the dose.

During therapy with the drug "Thiocetam" should refrain from driving the car, as well as from occupations by hazardous activities that require the speed of psychomotor reactions and increased concentration of attention.

Storage conditions

The agent in question should be stored in a place protected from light (sunlight) and out of the reach of children. The storage temperature of the preparation is 15-24 ° C. Its shelf life is two years.

Medication cost

How much does the drug "Thiocetam" cost? The price of this product can be different, depending on the mark-up of the pharmacy network, as well as on the form of release of the drug. The average cost of this medication is 460 Russian rubles.

Many patients who were prescribed such a drug, believe that this inflated price. Given that the medication should be taken for a long period (from several weeks to several months), treatment is quite expensive.