Thiamine is ... Thiamine: pills. Thiamin - vitamin B1

Thiamine (otherwise vitamin B1) is a colorless substance with a crystalline structure that is highly soluble in water. It has the chemical formula C ₁₂ H ₁₇ N ₄ OS.

In 1912, thiamine (vitamin B1) was first obtained from rice bran. The experiment was conducted by the biochemist from Poland Kazimir Funk. In this article we will tell you everything about this substance, we will describe what is its use for the human body, how it is used for medicinal purposes and what form of release it has. We hope that this information will be useful to you.

What is vitamin B1 for?

Thiamine is a substance that allows you to convert carbohydrates into glucose, which is considered the main source of energy. If the body does not get enough vitamin B1, it stops digesting the food well, which means splitting it up to simple sugars. As a result, the metabolism is seriously disturbed, the person begins to experience discomfort and pain: it suffers from insomnia, numbness of the extremities, falls into depression or becomes irritable.

A serious lack of vitamin B1 can lead to vitamin deficiency and the occurrence of the Beri-Beri disease, which is characterized by cardiovascular and nervous system damage due to an increase in the amount of pyruvic acid in the blood. Symptoms of the disease may include nausea, irritability, tearfulness, pain in the calf muscles, decreased performance.

Thiamine is the most important vitamin, the deficiency of which in extreme cases can lead even to metabolic coma and death. The lack of vitamin B1 is caused by malnutrition, including malnutrition, excessive consumption of coffee, tea, and alcoholism and gastrointestinal disorders. It is important to monitor the diet of your diet and, if necessary, seek qualified medical help.

Vitamin B1: benefit to the body!

Thiamine is a substance that plays a huge role in maintaining the normal functioning of many organs and body systems. It helps to carry out the proper work of the digestive, cardiovascular and circulatory systems, regulates blood pressure, promotes blood circulation through the vessels, strengthens the heart muscle and favorably affects the quality and composition of the blood, reducing its acidity. He also regulates the work of the nervous system, beneficially influencing the carrying out in the synapses of nervous excitation.

Thiamine for hair and skin health

It is widely used in cosmetology thiamine. This vitamin is necessary to maintain a normal skin condition, including the skin of the scalp. With a lack of vitamin B1, not only the skin but also the hair is seriously affected: its growth slows down, the appearance worsens, they become brittle and dull. To stop hair loss and stimulate hair growth, it is recommended to include in the diet food rich in thiamine. For the hair this will be the best panacea. When vitamin B1 deficiency is necessary, consult a doctor and take medications containing thiamine. Then your hair will be healthy, shiny and elastic.

What foods are rich in thiamine?

A little vitamin B1 is produced by the bacteria of the gastrointestinal tract, but this amount is not enough for the normal functioning of the body, therefore the main source of thiamine are various foods. To a greater extent, it is contained in plant foods: vegetables, cereals, legumes, and nuts. They are rich in peas, beans and soybeans, as well as broccoli, carrots, spinach, artichokes and rutabaga. Among the cereals, buckwheat, oatmeal and millet are distinguished by the content of vitamin B1. Some amount of thiamine is found in animal food, including beef, veal, pork, chicken.

A lot of it is contained in beer yeast and bakery products from wholemeal flour. If it is necessary to replenish the deficiency of vitamin B1, you need to use as many products with a large content of it or additionally take thiamine in ampoules or tablets.

Preparations containing vitamin B1

The daily requirement for vitamin B1 is as follows:

• In adults from 1.6 to 2.5 mg;
• In the elderly - from 1.2 to 1.4 mg;
• In pregnant women - from 1.3 to 1.9 mg;
• In children - from 0.3 to 1.5 mg.

These indicators can vary for a particular individual, depending on the physical loads, climate and the amount of carbohydrates consumed per day. When vitamin B1 is deficient, thiamine chloride and thiamine bromide preparations are used for medical purposes. They are synthetic analogues of natural vitamin B1, they are white or slightly yellowish powders, have a specific smell of yeast and easily dissolve in water. Thiamine chloride is produced in the form of ampoules (1 ml, 2 ml, 2.5% and 5%) and tablets of different dosage. Thiamine bromide is also produced in several variants:

• Tablets 0.0129, 0.00645, 0.00258 g (50 pieces per package);
• 6% and 3% solutions in ampoules 1 ml (10 pieces per pack).

Indications for use of vitamin B1

Most often synthetic drugs containing thiamine bromide or chloride powder are prescribed in the presence of hypo- and avitaminosis, neuralgia, radiculitis, paralysis of various origin. The main reasons for prescribing vitamin B1 are intoxication with mercury, carbon disulfide, arsenic and methyl alcohol, chronic alcoholism with memory disorder and impaired functioning of the peripheral nervous system. Ménière's disease, poliomyelitis, thyrotoxicosis, shingles, encephalomyelitis, Wernicke's disease are also indications for prescribing thiamine-containing medications. Vitamin B1 is prescribed for patients with gastric ulcer, intestinal atony, and myocardial dystrophy. Also helps people suffering from neurogenic dermatoses, psoriasis and eczema thiamine. The price for it varies between 20-40 rubles.

Method of application

Assign a drug with thiamine parenterally or inward. Adults are prescribed to take from 1 to 5 times a day tablets of 0.01 g. Dosage depends on the daily requirement for vitamin B1 and concomitant diseases of the patient. Children under 3 years of age are recommended to take the drug at 0,005 g once every two days, children 3-8 years - three times a day every other day, over 8 years - 0.01 g to three times a day.

Usually the course of thiamine is 30 days. If the patient has violated the absorption of the drug in the intestine or there is an urgent need to create high concentrations of thiamine in the blood, parenteral administration is prescribed . Thiamine is administered intramuscularly, the course of treatment can consist of 10 or more injections. Adults appoint 1 ml, and children 0.5 ml of vitamin B1 once a day. As a rule, thiamin (tablets and ampoules) is well tolerated. Intramuscular injections are painful because of the low pH of the solution. Rarely, adverse reactions are observed: urticaria, Quincke's edema, or skin itching. If the drug gets into the vein, the allergic reaction may be more serious, even anaphylactic shock is possible, so allergic diseases and intolerance in the anamnesis are a contraindication to taking a synthetic thiamin (vitamin B1) preparation.