The drug "Gliatilin". Instructions

The drug "Gliatilin" is included in the group of cholinomimetics of the central effect with the predominant effect on the central nervous system. The drug contains 40.5% of choline metabolically protected, which ensures its release in the brain.

The medication is available in the form of capsules for oral administration and ampoules for intramuscular and intravenous administration.

The active substance is choline alphoscerate. The capsule contains 400 mg of the active ingredient, in the ampoule - 1000 mg.

The active substance, getting into the body, is split into glycerophosphate and choline under the influence of enzymes. Choline takes part in the biosynthesis of one of the main mediators in nervous excitation (acetylcholine). Glycerophosphate is a precursor of frasfatidylcholine (phospholipid in the neuronal membrane).

Accumulation occurs mainly in the brain (up to 45% of the blood level), liver and lungs. In the form of carbon dioxide, lungs excrete 85%. 15% goes through the intestines and kidneys.

The drug has no effect on the reproductive cycle, does not have mutagenic and teratogenic properties.

The medicine "Gliatilin" is able to improve the transmission in the cholinergic neurons of nerve impulses, cerebral blood flow, positively affect the receptor functions and the plasticity of neuronal membranes, activate structures in the reticular formation, enhance metabolic processes, restore consciousness in traumatic brain injuries.

The active component of the drug has a corrective and preventive effect on certain pathogenic factors in the involutive psycho-organic syndrome-a change in the phospholipid composition in the neuronal membranes and a decrease in the cholinergic activity.

The drug "Gliatilin" is shown in the acute period of craniocerebral traumas with lesion mainly of stem character (a coma, a disturbance of consciousness, signs of lesions in the brainstem and others). The drug is prescribed for hemorrhagic and ischemic stroke in the reducing and acute phases. The "Gliatilin" medication is recommended for involuntary or degenerative cerebral syndromes of a psychoorganic nature, the consequences of cerebrovascular insufficiency. These conditions include multi-infarct dementia, Alzheimer's disease, as well as states accompanied by confusion, decreased motivation, ability to concentrate, initiative, development of disorientation. The drug "Gliatilin" instruction recommends when emotional instability, changes in the behavioral sphere, irritability, senile pseudomelanchia, a decrease in interest.

The drug is not prescribed for lactation, hypersensitivity, pregnancy.

The medicine "Gliatilin". Instructions for use

The drug is administered intramuscularly or slowly intravenously in the development of acute conditions - 1000 mg per day. Inside with cerebrovascular insufficiency of chronic course and syndromes of dementia, the drug "Gliatilin" instruction recommends taking three times a day for 400 mg.

The duration of the course is from three months to six months.

The side effect of the drug is nausea. In case of an overdose, this symptom may increase. If nausea occurs, reduce the dosage of the medication and consult a doctor.

The medicine "Gliatilin" is prescribed to children quite often. As practice shows the use of the drug in patients aged from one year and older, the medication is transferred quite well. The tool "Gliatilin" for children is a means of promoting the normalization of development. The drug has a positive effect on concentration of attention. Some parents note significant progress in the development of children. Very effective medication with long-term admission (two to three months, a minimum).