The preparation "Reopoliglyukin": instructions for use

"Reopoliglyukin" is a drug used in complex therapy of shock (traumatic, burn, septic, anaphylactic, cardiogenic), thromboembolic complications, obliterating vascular diseases, prolonged compression syndrome, purulent-septic conditions, retinal pathology, optic nerve, inflammatory processes of the cornea. The drug is also used in cardiac surgery, in which the device of artificial circulation is used. The drug in pediatrics is used to eliminate large blood loss by replacing the volume of plasma. The main form of release of the drug is a solution for intravenous infusion.

The drug "Reopoliglyukin". Instructions for use: composition, pharmacokinetics, pharmacodynamics

The drug contains the following active substances: dextran, sodium chloride. The auxiliary components include purified water, which is intended for injection.

The drug is not toxic, excreted from the body in a non-toxic form by the kidneys. Six hours after the administration, the active substance content is halved. Complete excretion is observed within a week.

An increase in the plasma content is observed in the first ninety minutes after using the drug. The active substance of the drug promotes the movement of fluids from the tissues into the blood. As a result, the viscosity decreases, the aggregation of the formed elements decreases. The drug has a powerful detoxification effect. Useful effects are noted after the administration of the drug for eight hours.

The drug "Reopoliglyukin". Instructions for use: dosage

To prevent the violation of capillary blood circulation, which is associated with a shock of different etiologies, intravenous solutions of the drug "Reopoliglyukin" are used in an amount of up to 1500 milliliters for one hour. In vascular surgery, the following proportion is used: per kilogram of body weight - ten milliliters of the drug (in the first stage). During the operation, the amount of the drug administered is half a liter. The rate of administration is determined by the severity of the patient's condition, by indications. In operations that are accompanied by the use of the apparatus of artificial circulation, ten milliliters per kilogram of body weight is added to the recommended doses.

The medicine "Reopoliglyukin". Instructions for use: side effects

Side effects include the appearance of skin itching, rashes, Quincke edema, the development of anaphylactic shock, arterial hypertension. The rapid administration of dextrans in significant volumes may lead to "dextran syndrome", which is characterized by damage to the lungs, kidneys, hypocoagulation. Infusion should be stopped immediately if there are complaints of difficulty breathing, a feeling of tightness in the chest, pain in the lumbar region, cyanosis, chills, circulatory disorders. The drug "Reopoliglyukin" during pregnancy should be prescribed in extreme cases, when there is a real threat to the life of the mother.

The drug "Reopoliglyukin". Instructions for use: contraindications

The main contraindications are: the presence of cardiovascular insufficiency, internal bleeding, craniocerebral trauma, thrombocytopenia, arterial hypertension, anuria, oliguria due to impaired renal function, hypersensitivity to components. If you have one or more of these diseases, do not use the drug "Reopoliglyukin". A description of all possible contraindications is in the detailed instructions.

The drug "Reopoliglyukin". Instruction: overdose

When using the drug in non-recommended doses, the following overdose symptoms may appear, which will be identical to the side effects, but with the most pronounced intensity.

The drug "Reopoliglyukin", for which there are many contraindications, is very popular in operating and extra-surgical practice. This is due to its high efficiency and the lack of analogues with improved pharmacological properties.