The drug "Fermatron": reviews of patients

Inflammation of the joints and accompanying diseases are frequent ailments. There are several types of drugs used for treatment, among them - "Fermatron." The patients' comments on this medicine show that it really copes with the task set before it - it really improves the mobility of joints and relieves pain in them. In the article the questions concerning this preparation are considered.

«Fermatron»: description

The Latin name of the drug is FERMATHRON. It is a viscous-elastic substance that is intended for injections into the synovial space of the joint. It is shown in a disease called "osteoarthrosis of large joints", caused by posttraumatic and degenerative changes.

In the production of this drug, new technologies for synthesis and purification have been used. Thanks to this, the medicine contains the equivalent of natural human hyaluronan. The substance acts in the following directions:

• Restoration of visco-elastic and protective properties of the joint fluid;
• Reduction of inflammatory reactions in the joints;
• Restoration of joints;
• Elimination of pain syndrome;
• Increased mobility of the joint;
• Restoration of homeostasis in the cartilage of the joint;
• Stimulation of the synthesis of its own hyaluronic acid.

Composition, form of release

The main active ingredient of the drug is sodium hyaluronate. It is a biological analogue of natural hyaluronic acid, which is produced in the human body.

This preparation is prepared for release in the form of a 1% sterile clear solution intended for intraarticular administration. The medicine is placed in a glass syringe, which is packed in a blister, and then into a cardboard box. The package contains one syringe, designed for a single injection. The syringe has a special protective rubber cap and thread for tight connection with the injection needle clutch . Such a design eliminates the leakage of the drug during administration.

A solution of 2 ml in volume, consisting of an active substance in an amount of 20 mg, which is dissolved in phosphate buffer, is placed in the syringe. The outer side of the syringe is treated with ethylene oxide, so it is sterile and fully ready for use.

During the clinical trial, the drug was found to have no toxic, mutagenic and allergic properties.

Properties of the preparation

"Fermatron", reviews about the application of which are already quite numerous, leaves no doubt about its useful properties. It has long been known how important is hyaluronate for the proper operation of joints. It is proved that it penetrates into the articular cavity, thereby stabilizing the structure of proteoglycans. And this, in turn, gives the cartilage elasticity and strength.

In addition, the drug reduces the activity of enzymes, which take part in the processes leading to the destruction of cartilage tissue. The medicine also shows the properties of the antioxidant and reliably protects the joint tissues from the harmful effects of free radicals. It is also important to stimulate the synthesis of its own hyaluronic acid, this has an undoubted positive effect on the musculoskeletal system.

Physically, "Fermatron" - a replacement joint fluid with hyaluronic sodium salt in the composition. Since the synovial, that is, the joint fluid, serves as a lubricant for the moving parts of the joint, a decrease in its volume in the case of various diseases leads to the defeat of this organ. In these cases, "Fermatron" (reviews of patients confirm this) restores the lack of fluid joint, thereby removing inflammation, increased friction and pain, and improves joint mobility and restores metabolism.

Effect of the drug

The effect of the drug "Fermatron" due to its physico-chemical properties and biocompatibility, since the drug contains an equivalent to human hyaluronan. This substance is a polysaccharide having a high molecular weight. It consists of repeating disaccharide residues of glucuronic acid and N-acetylglucosamine, which are the components of the joint synovial fluid. The substance is synthesized by fermentation of Streptococcus equi and then thoroughly cleaned. Hyaluronan functions as a kind of shock absorber under the action of direct loads on the joint and lubrication under lateral loads. It also stimulates synovial cells, carrying out the function of the filter, which does not pass molecules and cells that damage the cartilage.

Clinically reliable results are given by "Fermatron" (reviews of patients also confirm this) after the fourth-fifth injection. The effect of treatment persists to six months, sometimes more, after the last injection.

When a medicine is used

The use of the drug is shown mainly in the treatment of arthritis and arthrosis. In addition, the "Fermatron" is able to quickly stop pain, as well as relieve inflammation caused by trauma or degenerative processes inside the joint. It is possible to use this medication and with tight mobility of the knee and other joints.

The drug is also used in all stages of osteoarthritis, as well as after arthroscopic interventions.

Today, doctors quite often prescribe the drug "Fermatron plus". The patients' testimonies indicate that it actually helps to eliminate and alleviate the main manifestations of certain diseases.

"Fermatron": instructions for use, feedback

The first thing to remember is that this medication can not be used alone. Dosage, injection schedules and their number can be assigned individually only by a doctor after a preliminary examination and determining the degree of joint changes. And the procedure must necessarily be performed by a specialist in view of the fact that it is associated with direct insertion into the joint. Doing injections can be done on an outpatient basis and at home, by inviting a qualified health worker for this.

In a moderate course of the disease, as a rule, up to four to five injections are administered, which are administered once a week. The injection is made with a sterile needle of the appropriate size after preliminary treatment of the skin with an antiseptic. The medicine must have room temperature, the remnants of it are not used further and are disposed of together with a syringe and a needle.

If there is exudate inside the joint before the injection, it must be removed. The effect of the drug comes after the first injection.

Contraindications for use

You can not use "Fermatron" (the doctors' reviews are unambiguous) if the following conditions are observed:

• Violation of the integrity of soft tissues and skin in the joint region;
• Stasis of lymph or blood in the joint space;
• Significant inflammation and infection of the joints;
• Treatment of juvenile patients;
• Acute synovitis;
• Increased immunological response of the body to any of the components of the medication;
• Pregnancy and feeding - studies on the effect of the drug in these cases were not conducted. Perhaps appointment after a doctor's consultation.

Side effects

After the introduction of the drug "Fermatron" into the joint cavity (reviews of patients on this topic are almost not found), the sensation of warmth, redness, and swelling may develop. Also, post-injection edema and passing pain, and rarely inflammatory processes, can be disturbing. In such cases, a ten-minute imposition of a cooling compress on the joint is allowed.

Most often, these phenomena are short-lived and pass on their own, without additional therapeutical procedures. Allergy to the drug occurs extremely rarely.

"Fermatron": reviews and how it is transferred

The use of drugs with hyaluronic acid for intraarticular treatment in modern medicine often avoids serious complications and more complex treatments.

Sometimes after the first couple of injections, there is anxiety, discomfort and a feeling of restraint, but it quickly passes. And after the completion of the course of treatment, not only the unpleasant manifestations disappear, but also the symptoms of the disease. So, not very pleasant injection feelings pay off with more than the action of the drug.

The price of the drug "Fermatron", reviews of patients confirm this, is relatively high (about 5 thousand for one injection, plus or minus 200 rubles, depending on the pharmacy network and the city), but the effectiveness of the injections is worth it.

Virtually all who used this medication for treatment, note a quick return to active life, almost instantaneous disappearance of pain. Often the use of this drug gives a delay or completely postpones surgery for endoprosthetics.

Precautions and special instructions

The treatment can be carried out both in the conditions of a medical hospital and outpatient, with the observance of sanitary requirements.

During the treatment with the drug "Fermatron", reviews of patients and doctors in this converge, the patient can continue to engage in daily activities, protecting the site of the injection, that is, the problematic joint, from static and dynamic loads.

When prescribing a medicine, it is necessary to take into account the potential risk and immunological reactions associated with the introduction of biological material into the human body.

Do not use the product with damaged packaging.

There is no evidence that Fermatron is compatible with other drugs intended for intra-articular injection, therefore, their combined use is not recommended.

Do not use "Fermatron C" (instructions for use indicate this) in the presence of autoimmune atologies, for example, Bekhterev's disease.

Also, the joint use of this drug and pain medication is not recommended.

Analogs and conditions for storage

Treatment of joints can also be carried out by structural analogues of the preparation "Fermatron" according to the active substance. Here is their list:

• "Ostenil" (Ostenil) ;
• "Hyalurus";
• "Ostenil" plus (Ostenil plus);
• "Suplazin" (Suplasyn);
• "Fermatron S" (Fermathron S);
• "Durolane" (Durolane);
• "Ostenil mini" or "Ministhenil" (Ostenil mini, Miniostenil);
• "Synocrom Forte";
• "Fermatron plus" (Fermathron Plus);
• "Synocrom" ;
• "RusVisk" (RusVisc);
• "Synvisc" (Synvisc).

Store the drug in a dry, sheltered from sunlight, place and out of reach for children. The storage temperature should not exceed 25 ° C, the medicine should not be frozen.

Shelf life is three years, after the expiration of the specified time, the use of the drug is excluded. The medicine is subject to a doctor's prescription.