"Streptomycin sulfate": instructions for use, analogues and reviews

Modern medicine widely uses antibiotics to treat infections. By their appearance they literally made a revolution in medical practice. These are chemicals that can inhibit the death of bacteria and other pathogens. They differ in their toxicity and effect. They are used to treat not only people, but also animals. We will talk about one of these antibiotics further.

Form release and the principle of action of the drug

The drug "Streptomycin sulfate " is available in the form of a white powder without color and odor. Has a bitter taste. It is easy to dissolve. Destroyed in solutions of alkalis and strong acids with heating. It is produced in bottles of 1 gram of powder, from which the solution for injections is prepared.

And now a few words about how it works and what effect it has on the body.

"Streptomycin sulfate" - a preparation of bacteriostatic and bactericidal action. Active with respect to a large number of gram-negative and a certain number of gram-positive microorganisms, as well as in relation to the Koch's rod, which provokes tuberculosis. The drug is able to kill streptococci and pneumococci. Does not affect bacteria that can do without oxygen. And also on some microorganisms that cause infectious and viral diseases.

The action of the drug "Streptomycin sulfate " is the destruction of bacteria. Some kinds of them very quickly get used to the preparation and form stable forms. They then do not respond well to antibiotic therapy. Therefore, it is recommended to apply "Streptomycin Sulfate" not for a long time. The active active substance fights well against microorganisms that are at rest, unlike antibiotics with the active substance penicillin.

Streptomycin suppresses the processes of biosynthesis of enzymes, oxidative processes and the exchange of nucleic acids. The drug does not allow microorganisms to multiply, divide, break their normal metabolism and promote morphological changes in their structure.

The drug is well absorbed when administered intramuscularly. It persists in the blood up to 6-8 hours. It is excreted through the kidneys. When taking the drug inside is absorbed worse and is excreted through the intestine. It is necessary to approach with care to therapy if there are disturbances in the work of the kidneys.

To whom appoint

The drug "Streptomycin sulfate" application is quite wide. It is prescribed to people, but they are also used to treat animals. What diseases can be treated with this medication:

• Tuberculosis.
• Tubercular lesion of other organs.
• Pneumonia.
• Meningitis.
• Diseases of the urinary tract.
• Purulent-inflammatory processes.
• Plague and tularemia.
• Brucellosis.
• Endocarditis.

To treat many diseases apply "Streptomycin sulfate" in combination with other medicines, for example:

• "Levomycetin."
• "Tetracycline."

Which of them will be additional to achieve the best therapeutic effect, should the doctor decide with regard to the specific disease.

Who does not recommend the therapy with this medicine?

The instruction for use, which is valid for the drug Streptomycin Sulfate, indicates a number of contraindications for its use. They are as follows:

• Individual intolerance of the components of the drug.
• Hypersensitivity.
• Organic lesions of the auditory nerve.
• Diseases of the organs of hearing.
• Severe forms of cardiovascular disease.
• Renal insufficiency.
• Diseases of the liver.
• Diseases of the hematopoiesis.
• Systemic diseases, lupus erythematosus.
• Violation of cerebral circulation.
• Myasthenia gravis.

It should be noted that pregnant women and children are prescribed only by their vital signs.

How to use "Streptomycin Sulfate"

The instructions for use describe the following rules and dosages of the drug.

It should be noted that "Streptomycin sulfate" is used in adults in the form of injections, as well as aerosols in addition to the cavity of the trachea.

When administered intramuscularly, the dose for adult patients is usually 0.5-1.0 grams. Daily allowance should not exceed 2 grams. If the weight of a patient is less than 50 kilograms or is older than 60 years, the dosage should be at least 0.75 grams per day.

For children and adolescents, the amount of the drug is calculated depending on the body weight. For 1 kg of weight, the dose should be 15-20 mg and not exceed 0.5 grams per day for children and 1 gram for adolescents.

Such a disease, as tuberculosis, requires the introduction of a daily rate at a time. If the medicine is not well tolerated, then the total amount is divided by two times. Infections of non-tuberculous origin are treated by administration of a daily dose divided into 3-4 doses. The therapy lasts for 7-14 days.

If the kidneys are disturbed, the daily dose of the drug should be significantly reduced.

Preparation of solution for injection

Very important information about the drug "Streptomycin Sulfate" - how to breed it for various kinds of procedures.

For injection, the drug is dissolved in the liquid:

• Sterile water for injection.
• Fizrashvor.
• 0.25-0.5% solution of novocaine.

The proportion should be as follows: 1 gram of product per 4 ml of solvent.

A solution of "Streptomycin Sulfate" for injections is prepared immediately before use. It can not be stored, nor can it be heated.

For the introduction of the drug into the cavity of the trachea, the product is dissolved in the following ratio:

• 0.5-1.0 grams of the product in 5-7 ml of isotonic sodium chloride solution or 0.5% solution of novocaine.

It is prescribed up to 2-3 times a week, more procedures are not excluded.

To use the product in the form of an aerosol:

• For adult patients 0.5-1.0 grams of powder is diluted in 4-5 ml of saline. For warm-moist inhalation use 25-100 ml of solution.
• For children, the same dosage is used as for intramuscular injection.

The introduction of the drug into the cavity of the trachea, which was formed as a result of the necrosis of the tissues, is carried out with the help of a powder blower. A highly powdered powder and 10% solution are used. The procedure should be performed under the conditions of a surgical hospital, under the supervision of a doctor, no more than 1 time per day, the dose should not exceed 1 g of the drug Streptomycin Sulfate.

Treatment of animals

It should be noted that the drug "Streptomycin sulfate" for animals is very often an indispensable tool. Since it helps with various diseases, namely:

• Leptospirosis.
• Erysipelas of pigs.
• Bronchopneumonia.
• Mastitis.
• Wound and postnatal sepsis.

Contraindications for animals in many respects coincide with those for humans.

The drug is administered to the animals intramuscularly. For injections of "Streptomycin sulfate" the recipe for the preparation of the solution is as follows:

• It is necessary to take 10 ml of water for the preparation of solutions for injection or sterile saline.
• The powder is diluted at the rate of 0.25 g streptomycin per 1 ml of the solvent (the total dose is determined based on the body weight and age of the animal).
• The solution is prepared before use, stored and heated inadmissible.

For the treatment of animals, "Streptomycin sulfate" is used for a week. The dose is administered with a 12-hour interval intramuscularly.

When using the drug, it is possible to develop side effects both in humans and in animals. Let's consider them further.

Side effects

When using the drug, the following adverse reactions may occur:

• A sharp rise in temperature.
• Allergic manifestations.
• Dermatitis.
• Dizziness.
• Headache.
• Tachycardia.
• The appearance of protein or blood in the urine.
• Infringement of intestinal microflora.
• Diarrhea.
• Defeat of cranial nerves.
• Deafness.
• General weakness.

It is necessary to observe the dosage of the drug "Streptomycin Sulfate". The use of high doses can cause disruption of the vestibular apparatus. Symptoms of this phenomenon, as a rule, appear very early and are completely reversible after drug discontinuation. After a couple of months they completely disappear.

Therefore, when using this medication, it is recommended to perform thermal and audiometric tests in order to notice a violation of the vestibular function, as well as hearing problems. When working with the drug "Streptomycin sulfate" the instruction should be studied in order to avoid unwanted reactions.

Interaction with other drugs

This drug should not be taken with antibiotics that have a damaging effect on the hearing. To such it is possible to carry:

• "Kanamycin".
• Florimiin
• Ristomycin.
• "Gentamicin."
• "Monomycin".

Nephrotoxic drugs, including aminoglycosides, "Vancomycin", cephalosporins, possibly "Furosemide", and "Etacrynic acid" may increase the risk of aminoglycoside toxicity.

Do not use together with drugs that relax the skeletal muscles.

You should know something else about the drug Streptomycin Sulfate. Its formula is such that it does not allow mixing with antibiotics of the penicillin series.

Features of the drug use

It is important to follow all recommendations on the use of the drug. With prolonged contact with the active substance, dermatitis may develop.

Use of animal milk within 48 hours after treatment is not allowed. Slaughter can be made not earlier than a week after the last use of the drug.

Breast children prescribe "Streptomycin Sulfate" only in terms of vital signs.

It is advisable not to drive and control devices that require increased attention and concentration during the period of drug treatment.

It is forbidden to drink alcohol while treating Streptomycin Sulfate.

Analogues

Not always in the pharmacy you can find the necessary medicine. However, it is acceptable to use drugs analogs or drugs that are part of the same group. For the agent "Streptomycin Sulfate" analogues are:

• "Streptomycin - CMS"
• "Streptomycin - the chloralcium complex."
• Ampistrep
• The Endovert.
• Streptoline.
• "Stritsin".
• "Strizolin".
• Strepsulphate.
• "Diplompler".

Before taking an analogue of the drug, you need to consult a doctor.

Reviews about the drug

The drug belongs to the group of antibiotics and has been used for a long time to treat people and animals. It has long earned its authority in the treatment of many diseases. It is quite popular and effective in the treatment of tuberculosis.

A large number of good reviews receives the drug in the treatment of pets. They recover faster and get to their feet.

At present, a large number of new antibiotics have appeared that do not cause such dangerous consequences as deafness or violation of the vestibular function. Therefore, this drug for treating people is increasingly being used. However, there are many examples and reviews that speak about the effectiveness of this drug in the treatment of pyoinflammatory processes and tuberculosis. And to avoid undesirable side reactions, it is necessary to conduct treatment strictly under the supervision of a doctor, observing the dosage and rules for the preparation of solutions.