"Lancid": instructions for use, a description of the drug, analogs, reviews

Peptic ulcer of the gastrointestinal tract can occur suddenly. To treat such a disease, you should immediately contact an experienced gastroenterologist.

After a thorough examination, the doctor must prescribe antiulcer drugs. The most effective of them include the drug "Lancid". The price of this medication will be indicated below. In addition, you will learn about what properties are inherent in this tool, whether it has analogues and how to correctly take it.

Form of release, description, packaging and composition

The drug "Lancid" is available in the form of gelatin capsules (solid). They have a turquoise color and contents in the form of white granules.

The active ingredient of this drug is lansoprazole. Also in the capsules are the following auxiliary elements: mannitol, povidone, lactose monohydrate, cetyl alcohol, sucrose and hypromellose phthalate.

This drug is on sale in blisters and cardboard packs.

Effect of the drug

What is the drug "Lancid"? The instruction for use says that this is a specific inhibitor of K ⁺ -H ⁺ -ATPase (a proton pump). Its metabolism is carried out in cells (parietal) of the stomach. Active sulfonamide derivatives are formed.

This drug blocks the secretion of hydrochloric acid, reducing the stimulated and basal secretion.

Having high lipophilicity, this agent easily penetrates into the cells of the stomach (parietal), and then, concentrating in them, exerts a cytoprotective effect, increasing the secretion of bicarbonate and increasing the oxygenation of the mucosa of the main digestive organ.

The degree and rate of inhibition of stimulated and basal secretion of hydrochloric acid are dose-dependent. Its pH increases after 1-2 hours and 2-3 hours after taking 15 and 30 mg of the drug, respectively.

This medication has no effect on the gastrointestinal motility. The inhibitory effect of the drug manifests itself in the first four days of admission. After completion of treatment for 40 hours, the acidity remains below 50% of the basal level.

The withdrawal syndrome for such a drug is not typical.

Properties of the medicine

The drug "Lancid" (tablets) in the gastric mucosa forms specific IgA Helicobacter pylori, suppressing their growth and increasing the anti-Helicobacter pylori activity of other medicines.

It also inhibits the production of pepsin and increases the concentration of pepsinogen in the blood.

Kinetics of the preparation

Is the drug "Lanzid" absorbed? Instructions for use say that the absorption of this drug begins immediately after the drug leaves the stomach. The peak concentration of lansoprazole in the blood is observed after 1.7 hours.

Eating food reduces the absorption and bioavailability of the drug.

The half-life of lansoprazole is about two hours. This does not affect the duration of suppression of gastric secretion.

The withdrawal of medication from the body is carried out together with bile and urine.

Indications

At what diseases is the most effective medicine "Lancid"? Reviews say that this remedy cures the following diseases well:

• Reflux-esophagitis;
• Non-ulcer dyspepsia;
• Peptic ulcer (in the phase of exacerbation) of the gastrointestinal tract;
• Esophagitis erosive-ulcerative;
• Gastric ulcer stress;
• Zollinger-Ellison syndrome.

Contraindications

When should I not take Lancid capsules? Instructions for use asserts that the contraindications for the agent under consideration are the following patient conditions:

• breast-feeding;
• The first trimester of pregnancy;
• Malignant neoplasms in the organs of the digestive tract;
• Hypersensitivity to the elements of the drug.

With caution, this drug is prescribed for people with hepatic insufficiency, in the second and third trimesters of pregnancy, elderly patients and underage patients.

Medication "Lancid": instructions for use

These capsules are taken orally. They should be swallowed whole, without chewing.

With erosive-ulcerative esophagitis and gastric ulcer, medication is prescribed at 30 mg per day for 4-8 weeks. If required, the dosage is increased to 60 mg per day.

With stress ulcers and peptic ulcer of the duodenum, the drug is recommended to take 30 mg per day at a time. Do this preferably in the morning, at breakfast, for 2-4 weeks.

With Zollinger-Ellison syndrome, the dosage of the drug is selected individually.

When reflux-esophagitis medication is taken within a month in an amount of 30 mg per day.

To eliminate Helicobacter pylori the drug is recommended to use 30 mg twice a day. To improve the therapeutic result, the medication is combined with antibiotics such as Clarithromycin or Amoxicillin. Treatment should last at least a week.

With non-ulcer dyspepsia, the drug is used for 2-4 weeks at a dose of 15-30 mg per day.

With liver failure, as well as in elderly people, therapy starts with half the doses. Further, they are increased to the recommended, but not more than 30 mg per day.

Adverse events

The medicinal preparation "Lancid Kit" can cause the following side reactions:

• Headache, anxiety, malaise, drowsiness, dizziness, depression;
• A decrease or increase in appetite, hyperbilirubinemia, nausea, candidiasis of the gastrointestinal tract, abdominal pain, increased activity of liver transaminases, diarrhea, ulcerative colitis, constipation;
• Cough, upper respiratory tract infections, pharyngitis, flu-like syndrome, rhinitis;
• Skin rash, multiforme exudative erythema, photosensitivity;
• Anemia, thrombocytopenia;
• Alopecia, myalgia.

Drug Interactions

The drug "Lancid Kit" slows down the elimination of drugs that are metabolized in the liver through microsomal oxidation (for example, such as "Phenytoin", "Diazepam" and indirect anticoagulants).

The simultaneous use of lansoprazole slows down the pH-dependent absorption of drugs belonging to weak acid groups. Also, the drug in question accelerates the absorption of drugs that belong to the groups of bases.

"Lancid" interferes with the absorption of "ketoconazole", iron salts, "Ampicillin" and "Digoxin".

Lansoprazole reduces the clearance of "Theophylline" by 10%.

Sucralfate reduces the bioavailability of lansoprazole by 30%. In this regard, it is necessary to observe the interval between receiving the mentioned funds (in 30-40 minutes).

Lansoprazole is compatible with Indomethacin, Ibuprofen, Diazepam, Warfarin, Propranolol, oral contraceptives, and Prednisolone and Phenytoin.

Antacids should be prescribed 60 minutes before or 2 hours after taking "Lanzida", since they significantly slow down and reduce absorption of the latter.

Special Recommendations

Before and after therapy with Lancid, endoscopic monitoring of the patient's condition is required. This is necessary to exclude the development of a malignant tumor, since the treatment can mask the symptoms of the disease and delay the formulation of the correct diagnosis.

Price and analogy

How much are the capsules of "Lanzid"? Their price is about 200 rubles. If necessary, this tool can be replaced with other drugs. For this, you should consult a gastroenterologist.

Analogues of the drug in question are "Acrylanz", "Lansoprazole", "Helicor", "Lanzaptor", "Lanzap", "Lanzabel", "Loenzar-Sanovel", "Lansofed", "Epicurus".

Reviews

Most patients respond to the drug "Lancid" (medicinal analogues were presented above) only on the positive side. Consumers say that after several days of treatment, the unpleasant symptoms of peptic ulcer immediately disappear. Moreover, in combination with other medications, this agent promotes the rapid healing of erosions and ulcers on the mucous membrane of the digestive tract.

The disadvantages of this drug include a large number of adverse reactions. Although they can be avoided if all the requirements of the doctor are met.