"Itomed": instructions for use, description, analogues, reviews

For what purposes can a doctor prescribe a drug such as Itomed? Instructions for the use of this medication, as well as its indications, will be presented in this article. In addition, we will tell you whether there are analogues in the medicine under consideration, how much a drug costs, what side-effects arise against the background of its administration, etc.

Composition of the drug, description, packaging and form

What is the medicine "Itomed"? The instruction for use states that this preparation is white and coated with a tablet labeled "HC 803" on one side and risky on the other.

The active component of the drug is asprimary hydrochloride. Also, the preparation contains additional substances such as lactose, carmellose, corn starch, anhydrous silicic acid, hypromellose, magnesium stearate, macrogol, carnauba wax and titanium dioxide.

In the sale of tablets come in blisters (7, 14 or 10 pieces), which are placed in cardboard packs.

Principle of drug action

What are the tablets "Itomed"? Instruction for use informs us that the agent under consideration can improve the tone and strengthen the motility of the digestive system. This is due to antagonism with D2-dopamine receptors, as well as inhibition of acetylcholinesterase.

This drug is a stimulant for the release of acetylcholine (inhibits its destruction). In addition, the drug has antiemetic properties through interaction with D2-receptors that are in the trigger zone (it causes a dose-dependent suppression of the feeling of vomiting).

What other properties does the medicine "Itomed" have? Instructions for use indicate that the drug is able to activate propulsive motor motility of the stomach, and also have a specific effect on the upper gastrointestinal tract, accelerate transit through the stomach and improve its emptying.

One can not but note the fact that the tablets under consideration have no effect on the concentration of gastrin.

Pharmacokinetics

How long is the drug "Itomed" absorbed? Instructions for use (the description of the drug was presented above) contains information that this drug is absorbed well and quickly from the digestive tract. Its relative bioavailability is approximately 60%. The highest concentration in the blood is achieved after taking 50 mg of the drug after 1 hour.

The drug binds to proteins only by 96%. It is actively distributed in the tissues of the body and is found in the small intestine, kidneys, liver, stomach and adrenal glands. In therapeutic dosages, the drug penetrates insignificantly into the dorsal and brain, as well as into the mother's milk.

Metabolism of the drug occurs in the liver under the influence of flavin-dependent monooxygenase.

The medicine is withdrawn by means of the kidneys. Half-life is 6 hours.

Indications

In what cases do doctors prescribe a drug such as Itomed? Instructions for use (analogues of this remedy have the same indication) states that this remedy should be used for symptomatic therapy of non-ulcerative functional dyspepsia (i.e., chronic gastritis). Also, this drug is often prescribed to eliminate the following pathological conditions: a feeling of discomfort in the stomach, meteorism, anorexia, gastralgia, nausea, heartburn and vomiting.

Contraindications

When should not the drug "Itomed" be used? Instructions for use, expert reviews suggest that the contraindications for this drug are the following conditions:

• Deficiency of lactase;
• Bleeding from the intestine or stomach;
• Lactose intolerance;
• Perforation and mechanical obstruction of the digestive tract;
• Malabsorption glucose-galactose;
• Period of pregnancy;
• Children's age (tablets can not be taken until 16 years old);
• Lactation period;
• Hypersensitivity of the patient to astopride, as well as any additional substances that are part of the drug.

It should also be noted that the agent under consideration is given with special care to those people who take m-cholinomimetics and cholinesterase inhibitors, as well as to elderly people with reduced renal and hepatic function.

Medicinal preparation "Itomed": method of application and dose

The agent should be taken before meals. Usually tablets are prescribed in the amount of 1-st piece three times a day. The daily dosage (maximum) of the drug is 150 mg or 3 tablets.

For the treatment of the elderly, this dose is reduced.

If, for one reason or another, the tablets were not taken on time, then in the future the drug should be taken at regular intervals. Do not use the medicine in a double dose, in order to compensate for the missed.

Overdose

In the event that the patient has taken an increased dose of medication, then he is washed with the stomach, and also performs symptomatic therapy.

Interaction with other means

Is it possible to use the medicine "Itomed" simultaneously with other drugs? Instructions for use (the price of the medication will be presented at the very end of the article) informs that the drug in question is capable of accelerating the absorption of other medicines.

The prokinetic effect of the Itomed tablets does not change under the influence of drugs that reduce the acidity of gastric juice (for example, such as Cimetidine, Teprenone, Ranitidine, Cetraxate, etc.).

The cholinergic effect of the active substance of the drug may increase with simultaneous use of cholinesterase inhibitors and m-cholinomimetics.

M-holinoblokatory can reduce the effectiveness of taredropoda.

Lactation and pregnancy

Is it possible to use "Itomed" (tablets) during the gestation? Instructions for use, reviews, descriptions of this medication state that itprenide hydrochloride is contraindicated in pregnancy.

One can not but say that when taking the drug in therapeutic dosages, its active substance is insignificant, but still penetrates into the mother's milk. That is why after the appointment of this drug should stop lactation.

Side effects

Like most medical devices, the medicine "Itomed" also causes side effects. Among the most frequently manifested are the following deviations:

• Hematopoiesis: thrombocytopenia and leukopenia.
• Endocrine system: hyperprolactinemia and gynecomastia.
• The digestive tract: diarrhea, nausea, salivation increased, epigastric pain, jaundice and constipation.
• Nervous system: tremor, headaches, irritability, sleep disturbance and dizziness.
• Allergy: anaphylactic shock and urticaria.
• Laboratory indicators: hyperbilirubinemia, as well as increased activity of alkaline phosphatase, ALT, GGT and ACT.

Features of the drug

When signs of gynecomastia and galactorrhea appear, interrupt or stop therapy immediately.

In the treatment of biliary cirrhosis (primary), the patient may experience transient decompensation of the disease, which disappears immediately after the drug is discontinued.

During the period of therapy, the drug should be refrained from driving and doing hazardous activities that require special attention and concentration.

Price and analogues of the preparation

The price of the funds in question is quite high. For 40 tablets "Itomed" you will have to pay about 350 Russian rubles.

If for some reason you could not find the drug, it can be replaced by the following means: "Ganaton", "Itopra", "Itopride".

Patient Reviews

The patients' comments about the medicine "Itomed" are ambiguous. Some argue that this drug completely copes with the task. It eliminates the feeling of discomfort in the stomach, flatulence, nausea, heartburn and vomiting, and also treats anorexia and gastralgia.

However, some patients note that after using this remedy they significantly increased in weight (5-10 kg). There is also a category of people who did not notice any effect from taking the drug in question.

One can not help saying that a large number of patients complain about the high cost of the drug. Given that it must be taken three times a day for several weeks, such treatment (sometimes ineffective) is very expensive.