'Isoprinosine' for children - recommendations for use

"Isoprinosine" for children is an immunostimulating agent, is available in the form of oblong white tablets. They have a biconvex form, a strip on one side and a light amine smell.

Isoprinosine for children not only stimulates the immune system, but also has an antiviral effect. The use of this drug helps to restore the function of lymphocytes in conditions when the body is in immunodepression, blastogenesis in monocytic cells also increases, the expression of membrane receptors on the surface of T-helpers is stimulated, lymphocyte cells are not weakened, thymidine incorporation is normalized. Also, the use of isoprinosine stimulates the activity of cytotoxic T-lymphocytes and natural killers.

Isoprinosine for children shows antiviral activity in vivo against viruses Herpes simplex, measles and cytomegalovirus virus, type III T-cell lymphoma virus, influenza A and B, polioviruses, ECHO virus, equine encephalitis and encephalomyocarditis. The antiviral effect of the drug is provided by inhibiting the viral RNA and the enzyme dihydropteroate synthetase, which is involved in the replication of certain viruses. Thus, amplification of virus-suppressed RNA synthesis of lymphocytes occurs, and this in turn inhibits the translation of viral proteins and the biosynthesis of viral RNA, the production of lymphocytes that have antiviral properties of gamma and alpha interferons increases.

Isoprinosine - instruction

For children: after taking the drug, its rapid spread from the gastrointestinal tract occurs. Within 1-2 hours the maximum of the active substance in the blood plasma is reached . There is a rapid metabolism of inosine and uric acid is formed. It is excreted together with urine within 1-2 days and there is no accumulation in the body.

"Isoprinosine" is an antibiotic, therefore it is used in the following cases:

- the presence of infections that are caused by the virus Herpes simplex, it can be chicken pox, herpetic keratitis, labial and genital herpes, shingles;

- during treatment of influenza and ARVI;

- treatment of infectious mononucleosis, which is caused by the Epstein-Barr virus;

- presence of cytomegalovirus infection;

- Isoprinosine is also used for children in the treatment of severe measles;

- in the treatment of papillomavirus infection of the larynx and vocal cords ;

- with the appearance of molluscum contagiosum.

Contraindications for the use of this drug:

- the presence of an increased sensitivity of the organism to the components that enter isoprinosine;

- chronic renal failure, urolithiasis, arrhythmia, gout;

- can not be used for children under three years of age, or whose weight is less than 15 kilograms.

These tablets are taken only after meals, and they must be drunk with a large amount of water or other liquid. It is recommended to take 50 mg of the drug per kilogram of body weight, dividing the entire rate by 3-4 reception.

If the patient has severe forms of infectious diseases, then the indicated dose of the drug can be increased individually, but not more than 100 mg per kilogram of mass and be conducted for 4-6 receptions.

In the presence of acute diseases in children, the course of treatment with this drug is 5-14 days. The treatment process is carried out until the clinical symptoms disappear, and then another 2 days. Perhaps a longer treatment, which should be conducted under the strict supervision of a doctor.

Side effects from isoprinosine may be pain in epigastrium, constipation, joint pain, diarrhea, increased uric acid in the blood plasma, exacerbation of gout, dizziness, headache, polyuria.