Injections "Movalis". Reviews about injections "Movalis"

Anesthetics and anti-inflammatory drugs are particularly often used for joint diseases and neuralgia. Such drugs are very effective and effective. They reduce the severity of pain and ease the condition of the patient.

Unfortunately, these medications often cause the development of side effects. Therefore, they are recommended to use only on indications and for a short time.

The most popular among specialists and patients is the NSAID, such as "Movalis" (injections). The doctors' comments, the method of application and the testimony of the mentioned medicine, we will consider below.

Form, composition, description and packaging

The "Movalis" injections, which are mostly positive, are issued as a clear solution for intramuscular injection. It is yellow with a greenish tinge and goes on sale in colorless glass ampoules, which are placed in plastic contour pallets and carton boxes, respectively.

What substances contain the drug "Movalis" (injections)? Instructions (reviews about the drug you can find at the end of the article) informs that the active ingredient of this medication is meloxicam. In addition, the composition of the solution includes additional elements in the form of glycine, meglumine, glycofurfural, sodium chloride, poloxamer, sodium hydroxide and water.

Pharmacology

What is a solution like Movalis (injections)? The doctors say that the effectiveness of this medicine is very high. This drug is an NSAID. It has an antipyretic, anti-inflammatory and analgesic effect, and is also an enolic acid derivative.

The anti-inflammatory property of meloxicam is evident in the presence of any inflammation. The principle of its action is the ability of the active substance to inhibit the synthesis of prostaglandins.

Studies of this drug have shown that the drug at dosages of 15 and 7.5 mg does not have any effect on bleeding time and platelet aggregation. Also, experts have found that side reactions from the gastrointestinal tract when using meloxicam occur much less frequently than when using other NSAIDs.

Pharmacokinetics

What are the kinetic properties of the "Movalis" injections? Feedback from patients and doctors does not provide an answer to this question. Behind it you will have to refer to the instruction, according to which after intramuscular injection, meloxicam is absorbed completely. The relative bioavailability of this drug is almost 100%.

After the administration of the drug at a dose of 15 mg, its highest concentration in the blood is reached after 60-80 minutes.

The drug binds well to plasma proteins (by 99%), and quickly penetrates into the fluid synovial. Its metabolism is carried out in the liver, resulting in the formation of 4 inactive derivatives.

It is excreted to meloxicam through the intestine and through the work of the kidneys. The elimination half-life is 14-26 hours.

Indications

At what diseases can a "Movalis" solution be prescribed? Reviews (injections cause fewer adverse reactions than oral medications) doctors say that this drug is very effective in the initial period of treatment of pain syndromes. It is also used for short-term symptomatic therapy of ankylosing spondylitis, osteoarthritis, rheumatoid arthritis, degenerative joint diseases and arthrosis.

Contraindications

What contraindications have "Movalis" injections? Experts say that this drug can manifest itself from the negative side, if it is taken at:

• Hepatic or congestive heart failure;
• Hypersensitivity to the main components of the drug;
• Crohn's disease or ulcerative colitis;
• Erosion or ulcer of the digestive tract;
• Progressive kidney disease;
• Reception of anticoagulants;
• Renal failure;
• Liver diseases;
• Pregnancy;
• Bleeding in the gastrointestinal tract;
• Operational pain (shunting of the coronary arteries);
• Breastfeeding;
• Underage age.

Movalis solution: instructions for use

The injections, which are very frequent, are prescribed in patients with osteoarthritis at a dose of 7.5 mg per day. If required, this amount is increased to 15 mg.

With ankylosing spondylitis and rheumatoid arthritis, the medication is recommended to be used at a dosage of 15 mg per day. Depending on the therapeutic effect, this amount can be reduced to 7.5 mg.

People with an increased risk of side effects are treated with the lowest possible doses.

Is it possible to do injections of Movalis simultaneously with other NSAIDs? Experts say that such combinations are undesirable.

Intramuscular administration of the drug is only indicated at the very beginning of therapy. Later on they switch to oral preparations.

The medication is injected deep into the gluteus muscle. The drug should not be used intravenously, or mixed with other drugs (in the same syringe).

Adverse events

What side effects can the said medication and its use cause? "Movalis" (injections) often contributes to the development of the following reactions:

• Thrombocytopenia, anemia, changes in the number of blood cells, leukopenia;
• Drowsiness, headaches, dizziness;
• Anaphylactic shock, hypersensitivity reactions, anaphylactoid or anaphylactic reactions ;
• Vertigo, visual impairment, conjunctivitis, tinnitus, blurred vision;
• Mood changes, disorientation, confusion;
• Increased blood pressure, palpitations, flushes of blood to the face;
• Abdominal pain, gastritis, dyspepsia, stomatitis, diarrhea, bloating, nausea, gastroduodenal ulcers, bleeding from the gastrointestinal tract, belching, constipation, esophagitis, colitis, perforation of the gastrointestinal tract;
• bronchial asthma;
• Hepatitis, transient changes in liver function;
• Angioedema, Stevens-Johnson syndrome, pruritus, erythema multiforme, skin rash, toxic epidermal necrolysis, bullous dermatitis, hives, photosensitivity;
• Changes in renal performance, acute renal failure of urination, urinary retention;
• Cytopenia, glomerulonephritis, renal medullary necrosis, nephrotic syndrome.

The drug "Movalis": reviews

The "Movalis" injections are very painful. This is the opinion most patients adhere to. But despite this, they are often used for joint diseases. This is due to the fact that the drug in question is very effective.

The main drawback of this medication is the presence of a large number of adverse reactions and contraindications.