From what "Ampicillin" helps ?. Ampicillin tablets: instructions for use

The drug "Ampicillin", which has been popular for many years, is an effective antibiotic. Despite the fact that new drugs have appeared, it is still in demand among doctors and patients. This semisynthetic antibiotic penicillin series is effective against many bacteria, and from sepsis and purulent infection it helps better than others. Not everyone knows exactly what "Ampicillin" helps with, although its low price and availability in pharmacies make it one of the most purchased drugs. Many patients prescribe it themselves, which, of course, should not be done. The use of "Ampicillin" should be strictly according to the doctor's prescription, which takes into account the patient's health and the peculiarities of his illness. It is necessary to know precisely, from what "Ampicillinum" helps or assists, not to cause development of a superinfection, insensitive to antibiotics.

Characteristics of the preparation

This drug belongs to the group of semisynthetic penicillins and has a wide spectrum of action.

"Ampicillin" in tablets has been used for many years, since it is active against most bacteria. Its main active substance effectively destroys the cellular walls of microorganisms. "Ampicillin" suppresses metabolic processes in the membranes of their cells. Under its influence many gram-positive and gram-negative bacteria die, as well as pathogens of some intestinal infections. But there are microorganisms that release a special enzyme beta-lactamase. It destroys penicillin, and the drug is powerless to cure infections caused by such bacteria, for example, staphylococcus. But it effectively treats various mixed infections, purulent infection and sepsis.

Forms of the preparation

1. Earlier ampicillin tablets were quite popular. Instructions for use recommend using it for many infections. And now it is a fairly common antibacterial drug. Many patients buy for themselves with various ailments "Ampicillin". The price is not high, so the drug is one of the most affordable. Although it is not recommended to drink antibiotics without prescribing a doctor.

2. In severe forms of infections and in hospitals, "Ampicillin" is injected more often. Enter it intravenously or intramuscularly. The powder dissolves in special water for injections.

3. Now the preparation is issued in the form of a powder for the preparation of a suspension for oral administration. It is more convenient for patients who are difficult to drink a pill, especially children.

How does the medicine work?

The drug destroys the cells of bacteria. This leads to their death.

"Ampicillin" is quickly absorbed into the blood, the maximum concentration in the plasma is observed after several hours. And with intravenous or intramuscular injection - even earlier. But "Ampicillin" in tablets is quite effective. After all, the drug is resistant to the effects of stomach acid and does not break down in the gastrointestinal tract. Within a short time it accumulates in all the fluids and tissues of the body: it penetrates not only into the blood, but also into the lymph, bile ducts, spinal and intraarticular fluid, bones and skin. "Ampicillin" is excreted in the urine, but it is also actively excreted in breast milk, so nursing mothers are not recommended to take it.

Under what names can I buy the drug

1. "Ampicillin sodium salt". This is a low-toxic broad-spectrum antibiotic.

2. "Ampicillin trihydrate". The use of this drug for urinary tract infections is justified by the fact that it is excreted in the urine almost unchanged.

3. Actually Ampicillin. The price of this drug ranges from 20 rubles per package. This is one of the cheapest antibiotics.

4. "Ampioks". This is a combined preparation based on ampicillin. It also contains the antibiotic oxacillin, so it has a stronger effect.

5. More modern preparation "Amoxicillin". "Ampicillin" has the same composition and action. But doctors have recently begun to use it less and less.

6. The antibiotic in question can also be purchased under the following names: "Aminopen", "Biomitsin", "Decillin", "Penbrok", "Totomycin", "Zetsil" and others.

What is Ampicillin used for?

The given agent helps with the following diseases:

- bronchitis, pneumonia and even lung abscess;

- Otitis, sinusitis, tonsillitis or pharyngitis;

- Infection of the kidneys and gallbladder, it is especially effective in cystitis and urethritis;

- severe intestinal infections, including typhoid and salmonellosis;

- the preparation is effective against purulent wounds, infections of the skin and soft tissues, for example, in case of a face or dermatosis, postoperative inflammations;

- this is one of the few drugs that help with gonorrhea, chlamydia and meningitis;

- Ampicillin treats various infections of the musculoskeletal system, rheumatism, arthritis and osteomyelitis.

From what "Ampicillin" appoint or nominate still? It is effective in listeriosis and protea. The drug is also used as a prophylactic for endocarditis - inflammation of the heart muscle. Unlike other antibiotics of the penicillin group , this drug is very effective against pyogenic and hemolytic streptococci.

Contraindications to admission

But not everyone can drink "Ampicillin" (pills). The instruction warns against taking the drug of those who suffer from the following diseases:

- kidney failure or kidney disease;

- hepatic impairment;

- bronchial asthma;

- allergic diseases;

- severe violations of the functions of the digestive tract;

- mononucleosis or leukemia;

- a tendency to bleeding.

You can not take "Ampicillin" women who breastfeed. Tablets are not prescribed for babies under 6 years of age.

Side effects

During the administration of the medication, undesirable symptoms may appear. In this case, you need to consult a doctor about the drug discontinuation. What side effects can Ampicillin cause?

- Nausea, vomiting, abdominal pain and dry mouth. Very often, the intestinal dysbacteriosis develops.

- Dizziness, drowsiness, trembling of hands and feet.

- Headache, cramps.

- Rhinitis or conjunctivitis.

- Rash on the body, hives and other allergic reactions, up to anaphylactic shock.

- Dysfunction of the liver and hepatitis.

- Behavior change: depression, aggressiveness or anxiety.

- Propensity to bleeding due to a decrease in the number of platelets in the blood.

- The amount of hemoglobin and blood leukocytes is also reduced.

- There is often a development of fungal diseases on the background of taking the drug.

Ampicillin tablets : instructions for use

Depending on the health status and age of the patient, 250 mg to 1 g is prescribed at a time. Drink the medicine on an empty stomach, with plenty of water. Take "Ampicillin" four times a day, with equal intervals at six o'clock.

Usually they drink it half an hour before a meal or an hour after. If the drug is taken with food, then its absorption slows down, respectively, the therapeutic effect is reduced. Duration of admission depends on the disease. In severe cases, you can extend the course of treatment for 3-4 weeks and even more. But usually the drug is stopped after a couple of days after the disappearance of the symptoms of the disease. A solution of Ampicilin for injections can be prescribed to children from year to year, but treatment is performed in a hospital. The dose is calculated depending on the weight of the child - 50 mg per kilogram. The injections are done no more than two weeks, then treatment continues in adults with pills, and the children are changed the drug.

Special instructions for admission

- The drug is prescribed only after a study of the sensitivity of the microorganisms that caused the disease to it.

- Categorically contraindicated drinking alcohol during treatment.

- Weakened patients may develop superinfection, especially with prolonged medication. Bacteria acquire sensitivity to antibiotics.

- Simultaneously with taking "Ampicillin" it is recommended to drink vitamins of group B and vitamin C, as well as antifungal drugs, for example, "Nystatin".

- With long-term treatment with the drug, you need to monitor the condition of the kidneys and liver, as well as the organs of hematopoiesis, a regular blood test is necessary.

- When improving the condition, you can not stop taking Ampicillin (pills). The instruction recommends drinking it another 2-3 days after the disappearance of the symptoms. This is also true for other forms of medication.

- Like other antibacterial agents, Ampicillin suppresses the intestinal microflora and reduces the synthesis of vitamin K. Therefore, it is desirable to take antibiotics simultaneously with dysbacteriosis and vitamin complexes.

- From what "Ampicillin" is now appointed more often? It is more effective than other antibiotics in purulent wounds, ulcers, furunculosis, inflammation of the joints and cystitis.

Interaction with other drugs

- Antacids and laxatives, as well as food, slow the absorption of the drug and worsen its effect.

- Acorbic acid, on the contrary, accelerates the absorption of Ampicillin.

- Other bactericidal antibiotics strengthen the action of the drug, and bacteriostatic agents - oppress it.

- Nonsteroidal anti-inflammatory drugs and various diuretics increase the concentration of Ampicillin in the blood, thereby strengthening its effect.

- When taking this antibiotic, the effectiveness of estrogen-containing contraceptives is reduced.