But the spine

But the spawn (or drotaverin) belongs to the group of antispasmodics. The effect of the drug extends to muscle tissue and develops as a result of a decrease in the amount of calcium supplied to the muscles. This, in turn, causes inhibition of phosphodiesterase and the accumulation of cyclic adenosine monophosphate.

As a result, but the spine weakens the tone of the muscular system (in particular smooth muscles) and the peristalsis of the gastrointestinal tract. In addition, but the cavity causes vasodilation without affecting the autonomic and central nervous system. This feature allowed to apply the drug in those cases when spasmolytics of central action (that is, acting on the central nervous system) are contraindicated.

With intravenous administration, the effect begins to develop after two to three minutes, the maximum of its intensity falls on the time interval - "half an hour after the drug".

But the spawn is available in the form of injection solutions, tablets, capsules and tablets in the shell.

As spasmolytic but the spine has found application in the following conditions: gastroduodenitis, spasm of the muscular system of internal organs (with bile, renal and intestinal colic, dyskinesia of the gallbladder and outgoing tracts, with cholecystitis), spastic constipation, pyelitis, peptic ulcer.

In addition, but the spine is used for spasm of peripheral, as well as coronary and cerebral arteries. This explains the effectiveness but the spine with a headache of a spastic nature. This medical product has found its application in obstetrics and gynecology. It is used in case of threat of miscarriage, premature birth, algodismorrhea, spasm of throat of uterus and its prolonged opening during labor, as well as for arresting postpartum fights.

But the spine is also used for some diagnostic manipulations, for example, in cholecystocholangiography.

When using any medication, side effects and reactions may develop. So, when applying but the spines are possible: palpitation, dizziness, a feeling of heat, a decrease in the level of blood pressure, and various allergic reactions. When using the drug intravenously (that is, with the injection method of administration), it is possible to develop collapse, arrhythmia, atrioventricular blockade, as well as depression of the respiratory center.

But the spine: an overdose of the drug. It is manifested in most cases by a violation of atrioventricular conduction, a decrease in the excitability of the heart muscle, which ultimately can lead to cardiac arrest or paralysis of the respiratory center.

There is a certain number of contraindications to the use of this antispasmodic. With renal, hepatic or heart failure; With atrioventricular blockade of the second-third degree of severity, with arterial hypotension and cardiogenic shock. Do not apply but the spy and with significant atherosclerosis of the coronary arteries, prostatic hyperplasia and zakratougolnoy glaucoma, during lactation and in the first trimester of pregnancy.

So how do you take the right stuff? First, it is necessary to correctly choose the dosage of the drug depending on the pathology. The most suitable dosages are: when administered orally, for adults, from forty to eighty mg three times a day; When administered intramuscularly or subcutaneously, the dosage is the same, multiplicity: from one to three times a day. To stop an attack of renal, hepatic, or other colic, but the spine is administered intravenously in an amount of 40-80 milligrams. Perhaps the intra-arterial administration of the drug, in particular with spasm of peripheral vessels.

Dosage of the drug (single, single dose) for children under six years varies from ten to twenty mg, the daily dose (maximum for a given age) is 120 mg; At the age of six to twelve years, a single dose is 20 mg, daily 200 mg. In childhood, the drug is applied with a multiplicity of up to two times per day.