Urolilinogen in urine - what does it mean? Bilirubin and urobilinogen in urinalysis

Urolilinogen is a bile pigment released from urine. The name itself comes from the Greek word uron - urine, Latin bilis - bile, and Greek genesis - origin.

How is urobilinogen formed?

The majority of urobilinogen (80%) is formed from erythrocytes, more precisely, from bilirubin, which, in turn, is synthesized from hemoglobin. In fact, urobilinogen is a product of the utilization of red blood cells.

How does this happen? Molecules of hemoglobin, after serving their term, are disposed of. First of them indirect bilirubin is synthesized, which in the liver undergoes a number of transformations. As a result, direct bilirubin is synthesized , which, together with bile, enters the intestine. There, this substance, with the participation of microflora, undergoes further transformations. As a result of multiple biochemical reactions, a number of intermediates are obtained. Some of them, for example, such as sterkobilinogen and mesobilinogen, are absorbed back into the blood through the portal vein system.

Further, these substances are again transferred through the liver together with bile, but a small part of them is excreted in the urine - this is approximately 4 mg per day.

Urolinogen in the urine

What does it mean? Urobilinogen is a colorless substance. But standing out together with the urine, in the air turns into urobilin. Therefore urine, containing urobilinogen, after a while darkens in the air.

Urolilinogen in urine - what does it mean? Normally, in a small amount, this product of the final disintegration, which has served its term of hemoglobin, is contained in all. But the content in his urine in high concentrations is, more often than not, a sign of pathology.

Urobilin and urobilinogen are the so-called urobilin bodies or urobilinoids. What does urobilinogen in urine mean and how can it be determined?

How to determine urobilinogen in urine?

To do this, you need to pass a general analysis of urine. This indicator is included in this study. Urobilinoids are normal in urine are kept in very small quantities, they are practically not determined. The possible presence of pathology is indicated by a positive reaction to this substance. It can be from weakly positive, which is denoted by "+", to sharply positive "+++".

Uroilinogen - this substance is colorless, but when it interacts with oxygen it is converted into urobilin, darkens and acquires a dark yellow color. Therefore, in freshly collected urine, the level of urobilinogen is determined, and if it stays in the air for more than an hour, then determine urobilin.

UBG is the content of urobilinogen. Explanation

In modern laboratories, urinalysis is often performed on urine analyzers. As a result of this analysis, UBG indicates the level of urobilinogen in the urine. Traces of urobilinogen are contained necessarily in any normal urine.

The level of this indicator increases with hemolytic jaundice, that is, the destruction of erythrocytes right in the bloodstream, as well as with toxic lesions of the liver, chronic and acute inflammatory processes occurring in its tissues. Intestinal diseases (constipation, enteritis, food poisoning) also cause an increase in the level of urobilinogen in the urine. But its complete absence is observed with mechanical subhepatic jaundice, i.e. with complete overlapping of the bile duct with a stone. Thus, the complete absence of urobilinogen in the urine of adults means the cessation of bile flow into the intestine. The exception is newborn babies who are naturally breastfed for up to three months, because at this age urobilinogen from bilirubin is not yet recovering due to the lack of the necessary microflora in the intestine.

The rate of this indicator is 5-10 mg / l.

Urolinogen in the urine. What does it mean?

The norm of this substance in the study of urine "-". Its so small that research shows a negative result. The condition at which urobilin levels increase, is called urobilinuria.

Urohibin in urine - what does it mean? Let's list the pathologies in which this indicator is increased. This, in the first place, acute or chronic liver pathology, the condition in which the destruction of red blood cells and the disruption of normal operation of the intestine. Namely:

• Hepatitis or cirrhosis of the liver.
• Liver tumors are benign or malignant.
• Stagnant phenomena in the liver tissues.
• Hemolytic anemia, in which the disintegration of red blood cells - erythrocytes.
• Poisoning by chemical substances in which the decay of erythrocytes occurs. In this case, hemoglobin freely enters the blood plasma. This leads to increased formation of bilirubin, which is excreted in bile. And as you know, urobilinogen is formed from bilirubin.
• Acute or chronic inflammatory bowel disease.
• Parasites.
• Chronic constipation.
• Intestinal obstruction.

The increase of urobilin bodies is not an obvious pathology, but only its possible presence. In some states, a mechanism is triggered, in which excess bio-slags are discharged into the intestine, for example, with diarrhea. As a result, an additional load on the kidneys occurs, in this case, urobilinogen is detected - "traces" in the urine. What does it mean? It's just that the kidneys are doing their job well. In severe conditions, this indicator increases to a large extent.

The reasons for the absence of urobilinogen in the urine

The complete absence of urobilinogen in the urine can mean the fact that the bile duct is obstructed. At the same time, the intake of bile and, consequently, bilirubin - an integral component of it stops in the intestine. And as you know, urobilinogen is formed from bile. If there is no bile in the intestine, then the formation of urobilinogen does not occur.

What to do?

Urolilinogen in urine - what does it mean? What to do in this situation? First of all, do not panic. Negative emotions and emotional imbalance lead to stagnant phenomena in the body, which will further exacerbate the situation. With a sharp response to urobilin bodies, it is necessary to consult a doctor and it is possible to undergo additional studies that will help to find out the true cause of this situation.

Sometimes people who, due to some vital circumstances, do not sleep at night (for example, night shifts at work), the reaction to urobilinoids may be weakly positive. In this case, observing the day mode will correct the situation. The liver is particularly active from 21 hours to 3 am, provided that at this time a person is in a restful state. Therefore, night sleep helps to establish the work of this body.

Active lifestyle and physical exercise are beneficial for the work of the whole organism, and water procedures help to eliminate unnecessary slags through the skin.

With a high content of urobilin bodies in the urine, you can advise a milky-vegetable diet. It will help to adjust the work of the intestines.

Infusions of medicinal herbs will also help to bring the body back to normal, to adjust the work of the intestine and to remove excess slag. These are bitter herbs, for example, immortelle, wormwood, elecampane, tansy, milk thistle. To prepare medicinal infusion, take one large spoonful of dry raw material of any of the listed herbs and pour 0.5 liters of boiling water, insist for at least half an hour, then filter. Take it before meals by 1/4 cup.

Urozilinoids in the urine of a child

Normally, urobilinogen up to three months in healthy newborn infants who are breastfed is not determined. This is due to the fact that in the intestine does not occur the process of reducing bilirubin in strobobilinogen (urobilinogen) due to lack of intestinal flora. Therefore, in newborn children urine is almost colorless.

Urolilinogen in urine - what does it mean for a child? The increased content of this indicator in children, as well as in adults, may indicate a possible pathology. But, perhaps, this is a temporary condition, for example, with an intestinal disorder. To find out the exact cause, you need to contact the pediatrician. Only after additional research it is possible to determine what urobilinogen means in the baby's urine.

Urothilinoids in the urine during pregnancy

Pregnant women should be given a general urine test after each registration, before every visit to the doctor. During the gestation period, all the systems and organs of the woman are subjected to an additional load. Therefore, in order to timely detect and treat any pathology, it is necessary to monitor the state of health during pregnancy.

Urobilinogen in the analysis of the urine of a pregnant woman should be in acceptable quantities, ie, only trace its traces, or in quantitative content from 5 to 10 mg per liter. The total absence or increase of such an indicator as urobilinogen in urine - what does it mean in pregnancy? This is an excuse to conduct additional studies to detect a possible pathology.