The NSAID team. Candles "Indomethacin". Instructions for use

Rectal suppositories Indomethacin is a drug belonging to the NSAID group. It has antipyretic activity, analgesic and anti-inflammatory effect. The drug has a depressing effect on cyclooxygenase, which leads to a disruption in the synthesis of arachidonic acid and prostaglandins. The drug helps to suppress platelet aggregation. The medication weakens the pain syndrome, especially pain and stiffness in joints in the morning, at rest and during movement. Against the background of local use, puffiness decreases and erythema decreases. Anti-inflammatory effect develops after the first week of application.

Indications

Candles "Indomethacin" instruction for use recommends pain in the spine, articular syndrome. In particular, the indications include gout, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. The medication is prescribed for dysmenorrhea, traumatic inflammation in the joints and soft tissues, myalgia, neuralgia. As an auxiliary, the drug is recommended for cystitis, prostatitis.

How to apply Indomethacin candles

Suppositories are injected deep into the rectum. Before the introduction it is necessary to conduct hygienic procedures. Candles "Indomethacin" instruction for use recommends using after the therapy by intramuscular injection of the drug. Dosage of 50-100 mg / day. It is recommended to use the drug at night. In severe pathologies, the dosage regimen is determined personally. The maximum dose per day is 200 mg.

Candles "Indomethacin". Instructions for use. Adverse Reactions

On the basis of local use of the medicine, allergic reactions to mucous membranes and skin, itching in the anorectal area, irritation are most often noted. Rarely, rectal involvement, bleeding from the gastrointestinal tract, exacerbation of chronic colitis are rare.

Candles "Indomethacin". Instructions for use. Contraindications

The drug is not recommended for erosive ulcerative lesions in the gastrointestinal system, hypersensitivity. Contraindications include a disorder of the liver or kidneys, pancreatitis in severe form, pregnancy. Do not prescribe medication with recent bleeding from the rectum, in children up to fourteen years old, with proctitis, cracks or other anus damage.

additional information

Caution is observed in the treatment of elderly patients, if the patient has renal or hepatic pathologies, history of the gastrointestinal tract, arterial hypertension, dyspeptic manifestations during use. Dose adjustment may be required for epilepsy, cardiovascular disorders, immediately after surgery. If there is anamnestic data on intolerance to NSAIDs, the drug is allowed only in emergency situations. It is not recommended to use the medication simultaneously with acetylsalicylic acid. On the background of therapy should provide control over the condition of the picture of peripheral blood, the activity of the liver and kidneys.