The medicine 'Dzozamitsin'. Instructions for use

Antibiotic "Josamycin" instructions for use refers to the group of macrolides. The drug has a bacteriostatic effect, associated with the inhibition of protein synthesis of bacteria. High concentrations in the foci of inflammation provide a bactericidal effect.

The drug is active against intracellular microorganisms, Gram-positive and Gram-negative bacteria (aerobic).

The agent "Dzhozamitsin" after penetration into the digestive tract is absorbed quickly enough. The maximum concentration of the drug reaches after one or two hours.

The medication is characterized by a uniform distribution across systems and organs. The drug accumulates in the tissues of the pulmonary, lymphatic (in the palatine tonsils), in the organs of the secretion system, soft tissues and skin. There is a particularly high concentration in the lacrimal fluid, sweat, saliva, tonsils, lungs.

Excretion from the body is carried out mainly with bile, about twenty percent is excreted in the urine.

The drug "Jozamycin" instruction for use recommends the treatment of diseases of infectious-inflammatory etiology (nature) caused by sensitive microbes. Such diseases include infections in the upper and lower regions of the respiratory system and ENT organs: pneumonia (including atypical form), bronchopneumonia, scarlet fever (in the presence of hypersensitivity to penicillin), diphtheria (in combination with antitoxin), laryngitis, otitis media , Sinusitis, paratonzillitis, tonsillitis, pharyngitis and others. Medication "Dzhozamitsin" instructions for use and recommends for infections of the skin and soft tissues: lymphadenitis, lymphangitis, acne, erysipelas (with increased sensitivity to penicillin), anthrax, furuncles, pyoderma and others. The indications include periodontal disease and gingivitis, as well as other infections of the oral cavity. The drug "Jozamycin" is prescribed for urinary and genital infections: venereal lymphogranuloma, syphilis (with hypersensitivity to penicillin), gonorrhea, prostatitis, urethritis, as well as mycoplasmal, chlamydial and mixed infections.

Patients with fourteen years of medicine is recommended to take a dose of 1-2 grams in two or three doses. Children under 14 years of age are prescribed thirty to fifty milligrams per kilogram, divided into three doses. The duration of application is determined by a specialist.

Taking the drug may provoke a number of undesirable consequences. To the rare side effects of the drug "Josamycin" the instruction for use includes jaundice, disorders in the bile outflow, increased activity of liver enzymes, hives, hearing disorders (transitory dose-dependent). The drug may cause pseudomembranous colitis, diarrhea, vomiting, heartburn, nausea, worsening of appetite.

The drug is not prescribed for hypersensitivity to erythromycin and other antibiotics from the macrolide group. To the contraindications to the drug "Dzozamitsin" the instruction refers to violations of liver functions in the severe stage.

The physician determines the expediency of taking the medication during lactation and pregnancy.

At simultaneous application of hormonal contraceptives and preparations of group of macrolides it is recommended to use additional contraceptives (not hormonal).

When appointing newborns, systematic monitoring of liver activity is necessary. Preterm infants are contraindicated.

With the development of pseudomembranous colitis, the remedy should be abolished, while prescribing the necessary treatment.

Despite the fact that about the drug "Josamycin" reviews are more positive, before taking it is necessary to consult a doctor.