The drug "Preductal": reviews. "Preductal": composition, analogs and price

One of the most popular and popular drugs, effective in combating the symptoms of coronary heart disease, are the tablets "Preductal". Reviews about the use of this drug are contradictory. This is due to the fact that along with extreme effectiveness this medication does not heal the disease, but only removes its symptoms. The extent to which the use of the drug "Preductal" is advisable will be discussed in our article.

general characteristics

There are drugs, the use of which has earned numerous positive reviews. "Preductal" is one of them. This drug has the ability to neutralize the effects of oxygen starvation of the nerve cells of the brain and cardiac muscle by activating the metabolism. The drug "Preductal" improves energy metabolism in cells that are deficient in oxygen, so it is prescribed for patients suffering from coronary heart disease to prevent the onset of angina pectoris, as well as for retinal (visual impairment) and cochleovestibular (hearing change, dizziness, tinnitus) disorders .

Varieties

Currently, there are two types of the same medication - "Preductal" and "Preductal MB". They have the same therapeutic effect, since they contain in their composition one active substance - trimetazidine. So which of these drugs deserved the most laudatory reviews? "Preductal MB", some consider more effective, since it is created by a special technology, due to which its main active substance is released more slowly, and therefore, the effect on the body has a longer. There are no other differences between the two drugs. Everyone can choose one that for him, for personal reasons, seems better.

Dosage form

The dosage form of the drugs described above is almost identical. They are both available in the form of tablets. In the package with the medicine "Preductal" they contain sixty pieces, and "Preductal MB" is sold for 300, 180, 90, 60 units in a pack. Both of these tablets have a biconvex form and are colored on the break in white. However, there are some differences. Tablets "Preductal MB" pink, and "Reductant" - red-orange.

Composition

The drug "Preductal MB", which will be reviewed below, contains 35 mg of trimetazidine in one tablet. In a weaker "Preductal" this substance is present in a much lower concentration - only 20 mg. But the auxiliary components in these medications are different. "Preductal MB" consists of calcium hydrogen phosphate dihydrate, hypromellose, red iron oxide, colloidal silicon oxide. "Preductal" - from corn starch, aluminum yellow varnish, cochineal lacquer aluminum, mannitol talc. These drugs also have common components - glycerol, povidone, titanium dioxide, hypromellose, macrogol 6000, magnesium stearate.

Therapeutic effect

Trimetazidine maintains a stable level of ATP in the tissues and, due to this, provides normal life of the cell in conditions of oxygen deficiency. In addition, this substance inhibits the oxidation of fatty acids and stimulates the utilization of glucose, which is necessary for the formation of energy and requires less oxygen. It is this process that underlies the therapeutic effect of the drugs "Preductal" and "Preductal MB".

Patients' testimonials indicate that these drugs have the following properties:

• Slow down the development of a heart attack caused by physical exertion (from the fifteenth day of therapy).
• Reduce the fluctuations of blood pressure associated with excessive fatigue.
• Reduce the frequency and intensity of angina attacks.
• Eliminate the need for nitroglycerin.
• Stimulate blood circulation.
• Improve hearing for deafness caused by coronary heart disease.
• Increase the visual acuity associated with oxygen starvation.

Indications for use

• For ischemic heart disease, the tablets "Preductal MB" and "Preductal" are used. Reviews of cardiologists indicate that they are effective with prolonged therapy in order to prevent stenocardia attacks.
• To eliminate cochleovestibular disorders (dizziness, hearing loss, tinnitus) in ENT-practice, the drugs described by us also apply.
• In ophthalmology, the drugs "Preductal MB" and "Preductal" are no less in demand: they eliminate dystrophy and retinal atrophy caused by oxygen deficiency.

Instructions for use

Tablets "Preductal" must be swallowed whole during meals, washed down with a small amount of water. Usually they are prescribed one piece two or three times a day. Therapy, as a rule, lasts several months, its duration depends on the appointment of the attending physician. The daily concentration of the drug in the blood should not exceed 60 mg, which corresponds to three tablets. The use of more drugs is fraught with negative consequences, as evidenced by the reviews. "Preductal" in a strong concentration provokes pronounced side effects.

Tablets "Preductal MB" should be taken one at a time twice a day - in the morning and in the evening. They need to be absorbed without chewing, with food, with water. The daily maximum dosage of the drug in the blood is 70 mg (two tablets). To avoid side effects, it should not be exceeded. The duration of application of "Preductal MV" is also several months (under the close supervision of the treating specialist).

Side effects

Preparations "Preductal" and "Preductal MB" can cause the same side effects. Through clinical trials and prolonged monitoring of patients, it has been established that they can cause some disorders in the functioning of organs and systems.

• From the gastrointestinal tract can be observed: nausea, abdominal pain, diarrhea, constipation, vomiting, the phenomenon of dyspepsia (bloating, belching, gas leak, heartburn, etc.).
• From the side of the central nervous system: dizziness, asthenia, akinesia (the inability to perform arbitrary desired movements), headaches, tremor, instability in Romberg's pose, increased muscle tone, restless legs syndrome, specific parkinsonic flaccidity of the gait, drowsiness, insomnia.
• Skin and subcutaneous fatty tissue can suffer from rashes, itching, urticaria, acute generalized exanthematous pustules and Quincke's edema.
• From the cardiovascular system: extrasystole, palpitation, a strong decrease in blood pressure, tachycardia (frequent pulse), flushes to the skin of the face, orthostatic hypotension (pressure drop when moving to standing position).
• In the blood and lymph after the use of the drug, the following disorders can appear: agranulocytosis (decrease of basophils, neutrophils and eosinophils), thrombocytopenic purpura, thrombocytopenia.
• In addition, in some cases, the use of the drug described by us can cause hepatitis.

The fact that the aforementioned side effects disappear immediately after the drug has been discontinued is confirmed by numerous reviews. "Preductal", however, should be taken with caution, under the supervision of a doctor.

Patient Reviews

The use of the drug described by us causes numerous disputes. Most patients remain satisfied with the therapeutic effect, which causes the drug "Preductal MP". Reviews of its use allow us to think that it is very effective in removing pain, feeling squeezing and pinching in the heart. The disappearance of the above sensations significantly improves people's lives and allows them to forget about the chronic serious illness for a long time. In addition, many patients note that at the time of taking the medication, shortness of breath reduces and stamina increases. Some people have noticed that against the background of taking "Preductal" they have decreased the need for taking nitroglycerin.

Negative opinions about the drug are caused by subjective factors. So, some believe that cheaper domestic generics have imported "Preductal". Analogues (reviews about them are very diverse) are widely represented in the pharmaceutical market, and it is difficult to judge which of them is more effective. But many prefer proven "Preductal" to other medicines.

Reviews of cardiologists

Actively used in medical practice is the drug "Preductal". The doctors' comments pay attention to the fact that the quality of life increases dramatically in observed patients, stamina increases, the severity and frequency of angina attacks decrease. Experts confirm that the use of symptomatic drugs is advisable, since it allows people to temporarily forget about the serious diseases that plague them.

However, there are other opinions. Some doctors believe that the drug "Preductal" does not produce any positive effect. Reviews of cardiologists who literally believe in evidence-based medicine are based on the fact that this medication does not heal, but only eliminates the symptoms of severe diseases. From this position, some experts call the tablets "Preductal" an absolutely unnecessary placebo. So it or not - to solve patients who have experienced the effectiveness of this tool on their own experience.

Analogues

A lot of generics have the drug "Preductal". Analogues, reviews of which are very contradictory, can be found in any pharmacy. The most popular of them are Angiozil, Antisten, Vero-Trimetazidin, Deprenorm MB, Carditrim, Medarum, Metagard, Premedin, Prekard, Rimecor, Triducard "," Trimectal "," Trimet "," Trimetazid "," Trimetazidine "and many others. The question of the expediency of their use can be solved only by the attending physician.

Now you know what the drug "Preductal" is. Instruction, reviews, analogues of this medicine for you now is also not a secret. Remember that these "magic" pills do not cure, but only eliminate the symptoms. However, for many people suffering from serious diseases of the cardiovascular system, they are a real salvation and a pass to an interesting and active life.