The drug "Pangrol": instructions for use, description, composition and reviews

How much is and in what dosage can Pangrol be prescribed? Instructions for use, the price of this medication will be presented below. Also, you will find out in what form the given drug is on sale, whether it can be given to children, whether it has side effects and contraindications.

Description, composition, shape and packaging

In what packaging does the drug "Pangrol" come on sale? The instruction is enclosed in a cardboard box, where the preparation itself is contained (in blisters or a plastic jar).

The preparation in question is manufactured in the form of gelatinous, hard and opaque capsules of cylindrical shape. They contain small tablets, which have an enteric coating and a light beige color.

Also, this medicine can be taken in the form of biconvex tablets.

What substances are contained in the preparation "Pangrol 20000"? The instruction says that the active component of the tablets is pancreatin. Also included are crospovidone, lactulose monohydrate, talc, microcrystalline cellulose, polysorbate 80, silicon dioxide, simethicone emulsion, magnesium stearate, macrogol 6000, ethyl acrylate and methacrylic acid copolymer, sodium carboxymethyl cellulose and methylhydroxypropylcellulose.

As for the capsules "Pangrol 25000" (the method of administration and dose will be presented below), their active substance is also pancreatin. In addition, mini-tablets contain additional ingredients in the form of microcellulose, silicon dioxide, sodium croscarmellose, castor hydrogenated oil and magnesium stearate.

Also in the pharmacy you can buy intestine-soluble capsules "Pangrol 10000".

Pharmacology

What is the medicine "Pangrol"? The instruction informs, that the given preparation is digestive-enzymatic agent. It helps to fill the lack of substances that are necessary for the stable operation of the pancreas. In addition, the drug in question is capable of providing amylolytic, lipolytic and proteolytic effects.

Operating principle

What is the mechanism of action of the drug "Pangrol"? Instructions for use (the price of this medicine is quite high) reports that the powder from which the medicine is made is obtained during the processing of the pancreas of animals (in particular, pigs).

Enzymes contained in this drug, have a beneficial effect on the digestive system. They improve the process of digesting food, normalizing the pancreas.

Due to this effect, the drug in question can eliminate such unpleasant symptoms as abdominal pain, shortness of breath, a feeling of fullness of the stomach, gas formation, a feeling of heaviness in the abdomen.

The intake of capsules or tablets stimulates the stomach and intestines, as well as the pancreas, to produce enzymes that are directly related to the digestive process.

The bile extract, which is a part of the medicament, can enhance fat emulsification and display choleretic effects, improving the absorption and digestion of fats, as well as fat-soluble vitamins such as A, E and K.

Pharmacokinetic features

Is the medicine "Pangrol" absorbed? The instruction informs, that the given preparation is not absorbed by organs of the digestive tract.

Tablets and capsules are covered with an acid-resistant coating, which helps protect the drug from the effects of gastric juice. After the medication enters the intestine, its capsule dissolves and releases a drug substance that, when mixed with the contents, provides the required level of enzymes and their uniform distribution.

To achieve the maximum therapeutic result, experts recommend maintaining a slightly alkaline pH in the intestine.

The drug under consideration is treated with feces.

Indications

What is the purpose of the "Pangrol" medication? The instruction says that it is actively used for the substitution treatment of impaired pancreas. In addition, the drug in question is used for enzyme deficiency, which was caused by the following diseases:

• Intestinal infections;
• Narrowing of duct of pancreatic gland;
• Syndrome Shvahmana-Diamond;
• Pancreatitis;
• IBS;
• pancreas cancer;
• Cystic fibrosis;
• Disorders of the gastrointestinal tract.

It should also be noted that this medication can be prescribed to a patient before an x-ray examination or ultrasound of the abdominal cavity. It is also used to normalize the operation of the stomach and pancreas after surgery.

Contraindications

Can I prescribe Pangrol for children? The instruction says that this drug is acceptable for treating small patients.

Contraindications for taking the drug in question are the following conditions:

• Exacerbation of pancreatitis;
• Acute pancreatitis;
• Hypersensitivity to the ingredients of the drug.

Pangrol: instructions for use

The description of this medicine was presented above. Use it should only on indications.

The drug is taken in the process of eating, without chewing and washing with liquid. Its dosage should be determined by the gastroenterologist (depending on the condition of the person, the form and severity of the disease).

According to the instruction, the average therapeutic doses of this remedy are:

• Adult patients - 1-2 capsules of "Pangrol 25000" or 2-4 capsules of "Pangrol 10000";
• Dosage to children is calculated according to this scheme: 500-1000 units of lipase per kg of body weight.

As for the "Pangrol 20000", such tablets are usually taken for 1-2 pieces. If necessary, the gastroenterologist may increase the dose (but not more than 15,000-20,000 units of lipase per kilogram of weight).

The duration of therapy also depends on the patient's condition. If a person can not take the capsule in its entirety, its contents may be poured into liquid or food, which should not be chewed. The resulting mixture must be consumed immediately.

Side effects

At the time of taking the medication in question, the patient may experience such undesirable reactions as vomiting, bloating, diarrhea, abdominal pain, nausea, and other symptoms of digestive tract disorders.

Very rarely, patients are allergic to Pangrol (itching, urticaria, or skin rash). Such conditions require an urgent discontinuation of the drug.

Special Recommendations

The drug in question does not affect the ability of the patient to drive vehicles and work with complex mechanisms.

In the treatment of a disease such as cystic fibrosis, fibrosing colonopathy can develop in people who receive large doses of medication. To avoid such changes, prior to taking the medication it is necessary to undergo a medical examination in order to avoid the lesions of the colon.

Lactation and gestation period

The reliable results of clinical studies, which were aimed at identifying the consequences of the influence of "Pangrol" on the fetus, no. However, experts argue that pancreatin does not have toxic effects on the development of the baby. Therefore, the drug in question can be used during pregnancy and lactation, but only if absolutely necessary and prescribed by a doctor.

Analogues and price

To date, a huge number of drugs that promote normal digestion. The main analogs of the drug "Pangrol" can be considered such medicines:

• "Panzinorm".
• "Pancreatin".
• Mezim.
• "Pansinorm Forte."
• Festal.
• "Pancreatin Forte."
• "Gastenorm Forte."
• «Penzital».
• Creon.
• "Pancitrate".
• "Mikrazim."
• Enzistal-P.
• "Mezim Forte."
• Pancrelipase.
• "PanziKam".
• Pancreatin-LekT.
• The Hermitage.
• Panzim Forte.

The price of the medication in question depends on the form of its release. Packing "Pangrol 20000" with 50 tablets can be purchased for 1000 rubles. The cost of "Pangrol 10000" with 20 capsules is 250 rubles. And the average price of the drug "Pangrol 25000" (20 capsules) does not exceed 1100 rubles.

Reviews

Now you know what the preparation "Pangrol 20000" is. The instruction, price and indications for the use of this medication have been described above.

In the overwhelming majority of patients who took this medication, leave positive comments about it. "Pangrol" quickly and quite effectively eliminates all the symptoms of impaired digestion.

As for negative responses, in them patients report that it is necessary to calculate the dosage of this remedy very cautiously.