Instructions for the use of "Dicloberla". "Diclobert": price, reviews

For the treatment of diseases of the musculoskeletal system, diclofenac sodium-based drugs are used that exert anti-inflammatory, antipyretic, analgesic effects. One of these drugs is the drug "Diclobert". Instructions for use indicate the possibility of use in rheumatoid diseases, diseases of joints and muscle tissue.

Description

Medication refers to non-steroidal anti-inflammatory drugs of the first generation without a selective effect on cyclooxygenase. The drug is considered to be a derivative of phenylacetic acid.

Due to the active substance of diclofenac sodium, a pronounced anti-inflammatory effect is realized by inhibiting the biosynthesis of prostaglandin substances.

It is produced in a solid and liquid dosage form with a different dosage:

• The drug "Diclober 75" in the form of a solution for injection, packaged in ampoules of 3 ml with 75 mg of diclofenac sodium. The consumer package contains 5 ampoules.
• The drug "Dicloberl 50" in the form of tablets with an enteric-dissolving coating of 50 mg of active ingredient, packaged in blisters of 50 or 100 pieces in each.
• The drug "Diclobber-retard", produced in capsules with prolonged action with a dosage of 100 mg of diclofenac sodium. Packing in blisters for 10, 20 or 50 pieces.
• The drug "Dicloberte 50 suppositories" is produced in suppositories for rectal administration with a dose of 50 mg. Each blister has 10 or 5 suppositories.

It is produced by the German company Berlin-Chemie AG (Menaryini Group).

Mechanism of action

Instructions for the use of "Dicloberla" cause the anti-inflammatory effect of the drug by changing the various links in the pathogenesis of inflammation. First of all, they are associated with antiprostaglandin action, which reduces the production of prostaglandin mediators, the normalization of increased permeability and microcirculation processes, inhibition of platelet aggregation caused by adenosine diphosphate and collagen molecules, a decrease in histamine and bradykinin effect, a decrease in inflammatory processes and the removal of edema.

The analgesic effect is due to the ability to lower the allogeneic properties of bradykinin.

The antipyretic effect is aimed at calming the excitability flowing in the heat-regulating centers in the intermediate brain.

What is treated with the drug

Instructions for the use of Dicloberla Indicates the diseases associated with rheumatic lesions of the musculoskeletal system in the form of rheumatoid arthritis, rheumatism, osteoarthritis, ankylosing spondylitis.

The drug is used for gout, dystrophic joint changes,
With injuries of the skeleton and muscle tissue, accompanied by pain syndrome, edema and inflammation with inflammatory lesions of peripheral nerves, with primary dysmenorrhea.

How to take capsules

For the drug "Dicloberry retard," the instruction for use provides for the use of a dosage of 100 mg once a day. If there is a need to increase the dose, in parallel with the prolonged form take the tablets, covered with a special coating, or suppositories of 50 mg of diclofenac sodium.

Usually whole capsules are used immediately after ingestion, inside. Wash them with a large volume of water. For patients with disabilities of the digestive system, the medication is taken along with the food.

Dosing, depending on the degree of severity, is selected for each patient separately. The permissible limit of the daily content of diclofenac sodium for adult patients and children from 15 years varies from 50 to 150 mg.

How to take pills

This dosage form is intended for internal use during meals, so as not to damage the gastric mucosa. On the drug "Diclobert" instructions for the use of the tablet recommends to swallow whole and wash down with a lot of water.

The daily dose, which can be from 50 to 150 mg, is taken 2 or 3 times. The duration of treatment with the drug "Diclobber 50" instruction for use advises to set the doctor strictly individually, depending on the severity of the disease.

Application of the solution

For a deep intramuscular injection in the area of the gluteal muscle, injections "Diclober 75" are intended. Instructions for use establish a daily dose of 75 mg of diclofenac sodium, which corresponds to one ampoule, and the maximum amount of active substance per day should not exceed 150 mg.

The solution for parenteral administration is not intended for long-term treatment, for long-term therapy, tablets, capsules or suppositories are used.

Use of suppositories

Instruction for the application of "Dicloberla" in the form of a suppository of 50 mg has recommendations A relatively deep introduction into the rectum, which is carried out after the bowel has been emptied. The doctor determines the dosage individually for each patient, based on the severity of the lesion. The amount of active ingredient per day should be in the range of 50 to 150 mg when used by adults and patients after 15 years. Usually, this dose is taken for 2 or 3 doses.

Application Features

Instructions for the use of "Dicloberla" details the cases in which caution is needed in the application of the medication. Such conditions include liver and kidney diseases, erosive and ulcerative lesions, inflammatory processes in the intestine that occur in the present or in the past, dyspepsia, bronchial asthma, arterial hypertension, heart failure, surgical interventions, and elderly age.

If there are indications in the history of possible allergic reactions to non-steroidal anti-inflammatory drugs and sulfites, diclofenac-based medicines are used only for emergency treatment.

In the event of a severe hypersensitivity reaction, which can develop at the first administration, it is necessary to cancel the treatment and carry out urgent medical manipulations.

The instruction for the use of the Dicloberte stipulates that the treatment process must be accompanied by a systematic control of the functional characteristics of the kidneys and liver, peripheral blood should be checked. The period of therapy with the drug is not recommended to combine with the use of alcoholic beverages.

When the porphyrin exchange, acute intermittent porphyria , red systemic lupus, mixed collagenosis is disrupted, the drug is prescribed after a careful weighing of the benefit-risk ratio from treatment.

Careful medical supervision is required by patients who have allergic or chronic obstructive diseases of the respiratory system, because of the increased risk of allergic processes. Such reactions may manifest as bronchospasm, Quinck's edema or urticaria, as well as an increase in sensitivity to other allergens.

Under the action of diclofenac sodium, aggregation of platelets can be reduced. In connection with this peculiarity of treatment for patients with impaired blood coagulation, constant monitoring of the state of health is necessary.

Because of the possible development of adverse reactions from the central nervous system, associated with fatigue, dizziness, reaction and loss of attention, the ability to manage motor vehicles and complex mechanisms may be impaired.

Reviews

People with different diseases of the musculoskeletal system express their opinion on the effectiveness of the drug. Many medications can cope with pain and inflammation in joint arthrosis, painful sensations during limb movement, and at a time when the diagnosis is not yet established.

In most cases, you can hear a positive evaluation of treatment with Diclobert. Instructions for use of negative reviews are described in the "Adverse Reactions" section. This does not mean that the undesirable consequences of taking diclofenac sodium should necessarily appear.

There are opinions that indicate the effectiveness of the drug only for the period of treatment of the disease. Some patients believe that the remedy does not cure a person of the disease, but only reduces the pain caused by the ailment. There are people who are afraid to take the drug or restrict its use because of the negative effects on the liver.

There are positive reviews about the treatment of acute back pain with «Diclobert» injections. It was enough to introduce a solution of the drug, like pain and swelling began to decrease, and after the second injection all symptoms of the disease disappeared. The patient returned to normal life without suffering.

The drug is used in cases where other non-steroidal anti-inflammatory drugs do not produce a noticeable result.

Price

For patients it is very convenient, when there is an instruction for use in each pack for the Dicloberte drug. The price of each dosage form of the drug is different.

If the treatment is administered by intramuscular injection, pharmacies can buy a package with 5 ampoules of 3 ml of solution in each with a dosage of 75 mg. One pack will cost 430 rubles.

You can apply rectally the drug in the form of suppositories, this information contains the instructions for use on the Dicloberte drug. The price for a package of 10 candles will be an average of 470 rubles.

For oral administration, tablets of 50 mg of diclofenac sodium are used. The cost of 50 pieces in a pack is about 395 rubles.

If a dosage form with a prolonged action is needed, retard capsules of 100 mg of active ingredient are used. Buy 20 pieces you can for 460 rubles.