The drug "Alfadol-Ca": instructions for use, description, composition, analogues. "Alfadol-Calcium": reviews, prices

What is the drug Alfadol-Ca (Alfadol Calcium)? Instructions for use, price, analogs and indications for the purpose of this drug will be discussed below.

Basic composition, packaging, description and form

The drug "Alfadol Calcium", the instruction for which is contained in a pack of cardboard, is available in the form of soft gelatin capsules. Their main components are alfacalcidol and calcium, which is presented in the form of calcium carbonate and is made from shells of oysters.

In the sale of the drug in question comes in contour cells, which are packed in boxes of paper.

Pharmacodynamics of the drug

The drug Alfadol Calcium (instructions for use, the price of this medication will be discussed below) is a combined agent that regulates the exchange of phosphorus and calcium. The intake of this medication contributes to replenishment of the lack of vitamin D3 and calcium in the human body.

"Alfadol Calcium" is intended to increase the concentration of 1,25-hydroxycolecalciferol in the bloodstream. Thanks to this, the body absorbs not only calcium, but also phosphate, and also improves mineralization and decreases bone resorption. In addition, against the background of taking this drug in patients normalizes the content of parathyroid hormone in the blood, bone and muscle pains are eliminated.

Features of the medicinal product

What is remarkable about such a medicine as Alfadol-Ca? Its active substance takes part in the process of blood clotting, bone formation, transmission of nerve impulses, as well as in contraction of skeletal muscles and regulation of heart function.

It should also be noted that the drug in question contributes to the enhanced absorption of calcium from the digestive tract, and also improves the patient's condition in osteoporosis.

Kinetics of calcium-containing agent

Absorption of the drug "Alfadol-Ca" is high. Its highest concentration in the bloodstream is observed after 9-18 hours. It comes into contact with specific alpha globulins, and is also metabolized in the liver to form an active metabolite, such as calcitriol. A small part of this remedy is metabolized in bone tissue.

Vitamin D3, contained in this drug, does not affect the functioning of the kidneys. This allows you to assign it to people with kidney failure.

The drug is given with bile and by means of kidneys in the same amount.

Indications for calcium intake

At what diseases do you use the drug Alfadol-Ca (Alfadol Calcium)? Experts say that this remedy is very often prescribed when:

• Renal osteodystrophy;
• Osteoporosis (menopausal, senile, steroid, idiopathic and others), as well as with its complications (including fractures of bones);
• Hyperparathyroidism and hypoparathyroidism (with bone damage);
• Renal failure of a chronic nature.

Contraindications to the use of calcium-containing drug

In what cases is it forbidden to use the medicine "Alfadol-Ca" ("Alfadol Calcium")? The instruction warns that it can not be assigned if the following ailments are present:

• Urolithiasis (that is, the formation of calcareous stones);
• Increased sensitivity of the patient to vitamin D3;
• Hyperphosphatemia (except when it develops against the background of hypoparathyroidism);
• Increased level of calcium in the blood;
• Increased activity of parathyroid glands, hypervitaminosis of vitamin D, metastases of tumors in the bone, osteochondrosis);
• Hypermagnesia;
• Intolerance to soy or peanuts;
• Zollinger's syndrome;
• Underage age.

With caution, this drug should be taken to people who suffer from kidney failure, as well as those who are on hemodialysis. With prolonged treatment, the amount of calcium secreted by the kidneys should be checked every few weeks.

The drug Alfadol-Ca (Alfadol Calcium): instructions for use

The price of the funds in question is quite high. We will introduce it below.

The dosage of this drug is selected depending on the indications.

In case of osteoporosis, the medication is prescribed in the amount of 1-2 capsules per day.

With hyperparathyroidism and hypoparathyroidism, which are accompanied by bone damage, Alfadol-Ca should be used 1-2 capsules per day.

In osteodystrophy, as well as with chronic renal failure, this drug is recommended to take 2 capsules per day.

The duration of treatment with this medicine is determined by the doctor.

Occasional phenomena

What side reactions can cause Alfadol-Ca (Alfadol Calcium)? The instruction states that in the course of treatment with this remedy, patients may experience disruptions in the operation of certain systems:

• The digestive tract: diarrhea or constipation.
• Processes of metabolism: hypercalcemia. People with severe renal dysfunction may develop hyperphosphataemia.
• Urinary system: nephrocalcinosis.
• Allergies: rash, itching, urticaria.

Overdose

Hypercalcemia, which has developed amid high doses of medication, is manifested by malaise, weakness, fatigue, dizziness, headache, drowsiness, dry mouth, nausea, constipation, heartburn, diarrhea, vomiting, gastrointestinal upset, abdominal pain, muscle pain, Pain in the joints, pain in the bones, itching.

With the development of such symptoms, you should immediately stop taking the medication.

The severe course of hypercalcemia requires supportive treatment with the introduction of saline infusion solutions, and in some cases - the appointment of corticosteroids and diuretics.

In case of acute overdose, a preliminary treatment of the patient should be performed by rinsing the stomach or introducing mineral oil. Such actions help to reduce absorption and increase the excretion of medication through the intestine.

Interaction

Hypercalcemia in people taking cardiac glycosides increases cardiac arrhythmia, so their joint use should be avoided.

Patients who are systematically receiving anticonvulsants and barbiturates need to increase the dose of Alfadol-Ca to achieve the required result.

Absorption of this drug may disrupt concurrently taken mineral oils (especially with prolonged intake), as well as colestipol, colestyramine, sucralfate and large amounts of aluminum-containing antacids.

With the simultaneous use of this drug with laxatives, antacids, drugs containing magnesium, as well as in people on hemodialysis, it is necessary to take into account the possible development of hypermagnesia.

The drug Alfadol-Ca (Alfadol Calcium): analogues and cost

Replace this drug with such drugs as Oxidevi, Alfa D3-Teva, Alfacalcidol, Alfadol, Tevabon, Van Alpha and others.

You can buy the mentioned product in capsules for 380-450 rubles.

Reviews about the tool

According to experts, this drug contributes to increased intestinal absorption of phosphate and calcium. In patients with renal insufficiency, the concentration of these elements should be regularly monitored. It is also required to monitor the concentrations of phosphate, calcium, magnesium, alkaline phosphatase and creatinine.

As for the patients, they claim that Alfadol-Ca is doing its job well. However, it should be noted that they often have such side effects as hypercalcemia or hypercalciuria. Such conditions can be easily eliminated by canceling the medication.

Also, the drawbacks of this remedy include its high cost and the inability to apply to people with urolithiasis and in childhood.