The best antihistamines are 4 generations

About what are antihistamines, people who periodically suffer from allergies know the best. Sometimes only a timely medication can save them from painfully itchy rashes, severe coughing, swelling and redness. Antihistamines of 4 generations are modern means that affect the body instantly. In addition, they are quite effective. The result from them persists for a long time.

Effects on the body

To understand what distinguishes antihistamines of 4 generations, it is necessary to understand the mechanism of action of antiallergic drugs.

These drugs block the H1 and H2 histamine receptors. This helps to reduce the reaction of the body with the histamine mediator. Thus, the allergic reaction stops. In addition, these drugs serve as an excellent prophylaxis of bronchospasm.

Consider antihistamines of all generations. This will allow us to understand the advantages of modern means.

First Generation Medicines

This category includes sedatives. They block H1-receptors. The duration of action of these drugs is 4-5 hours. The drugs have a good anti-allergic effect, but they have a number of drawbacks, among which:

• Dilated pupil;
• Dryness in the oral cavity;
• Blurred vision;
• drowsiness;
• Decrease in tone.

Common drugs of the first generation are:

• "Dimedrol";
• "Diazolin";
• "Tavegil";
• Suprastin;
• "Peritol";
• "Pipolphen";
• Fenkarol.

These drugs, as a rule, are prescribed for people suffering from chronic diseases, in which there is difficulty breathing (bronchial asthma). In addition, they will have a beneficial effect in an acute allergic reaction.

Preparations of the 2nd generation

These drugs are called non-sedatives. Such means no longer have an impressive list of side effects. They do not provoke drowsiness, a decrease in brain activity. In case of allergic rashes and itching of the skin, drugs are in demand.

The most popular drugs are:

• "Claritin";
• "Treksil";
• "Zodak";
• Fenistil;
• "Histalong";
• Semprex.

However, a major drawback of these drugs is cardiotoxic effects. That is why these drugs are banned for use by people suffering from cardiovascular pathologies.

Medicines of the 3rd generation

These are active metabolites. They have excellent anti-allergic properties and are characterized by a minimal list of contraindications. If we talk about effective antiallergic drugs, then these drugs just represent modern antihistamines.

What are the most popular drugs in this group? These are the following medicines:

• Zirtek;
• "Cetrin";
• "Telfast".

They do not have a cardiotoxic effect. Often they are prescribed for acute allergic reaction and asthma. Excellent results they provide in the fight against many dermatological diseases.

Preparations of the 4th generation

Recently, specialists invented the latest drugs. These are antihistamines of the 4th generation. They are characterized by the speed of action and the long-lasting effect. Such drugs perfectly block H1-receptors, eliminating all the undesirable symptoms of allergies.

The great advantage of such medications is that their use does not harm the functioning of the heart. This allows us to consider them sufficiently safe means.

However, one should not forget that they have contraindications. Such a list is rather small, mainly it is a child's age and pregnancy. But still it is recommended to consult your doctor before use. It is not superfluous to study the instructions in detail before using antihistamines of the 4th generation.

The list of such medicines is as follows:

• "Levocetirizine";
• "Erius";
• Desloratadine;
• "Ebastin";
• "Fexofenadine";
• Bamipin;
• Fenspiride;
• "Cetirizine";
• Xizal.

The best drugs

It is quite difficult to distinguish among the drugs of the 4th generation the most effective. Since such drugs were developed not so long ago, there are few newer antiallergic agents. In addition, all preparations are good in their own way. Therefore, it is not possible to isolate the best antihistamines of the 4th generation.

Drugs containing phenoxofenadine are highly sought after. Such drugs do not have a hypnotic and cardiotoxic effect on the body. These funds today rightfully occupy the place of the most effective antiallergic medicines.

Derivatives of cetirizine are often used to treat skin manifestations. After eating 1 tablet, the result is noticeable after 2 hours. In this case, it remains for a fairly long time.

The active metabolite of the known "Loratadin" is the medicine "Erius". This drug is about 2.5 times effective than its predecessor.

"Xizal" medicine deserved great popularity. It perfectly blocks the release of inflammatory mediators. As a result of this effect, this remedy reliably eliminates allergic reactions.

The medicine "Cetirizin"

This is quite an effective tool. Like all modern antihistamines of the 4th generation, the drug in the body is practically not metabolized.

The drug has proved to be highly effective in skin rashes, as it is able to penetrate perfectly into the epidermal covers. Long-term use of this drug in infants suffering from early atopic syndrome significantly reduces the risk of progression of such conditions in the future.

2 hours after taking the pill, the necessary persistent effect comes. Since it persists for a long time, it is enough to take 1 pill per day. Some patients to take the necessary result can take 1 tablet every other day or twice a week.

The medication has a minimal sedative effect. However, patients suffering from kidney pathology should use this remedy extremely cautiously.

The drug in the form of a suspension or syrup is allowed to use crumbs from two years.

The medicine "Fexofenadine"

This agent is a metabolite of terfenadine. Such a drug is known and called "Telfast". Like other antihistamines of the 4th generation, it does not cause drowsiness, is not metabolized, and does not affect psychomotor functions.

This remedy is one of the safest, but highly effective drugs among all antiallergic medications. The drug is in demand for any manifestations of allergies. Therefore, doctors prescribe it for almost all diagnoses.

Anti-histamine tablets "Fexofenadine" are prohibited for admission to children under the age of 6 years.

The drug Desloratadine

This medicine also belongs to popular antiallergic drugs. It can be used for any age groups. Since pharmacologists have been proven to be highly safe, such a drug is dispensed in pharmacies without a prescription.

The drug has a small sedative effect, does not have a harmful effect on cardiac activity, does not affect the psychomotor sphere. Often, the medicine is well tolerated by patients. In addition, it does not interact with other medications.

One of the most effective medicines from this group is the drug "Erius". This is a powerful antiallergic medicine. However, during pregnancy it is contraindicated. In the form of syrup, the medicine is allowed to take babies from 1 year.

The drug "Levocetirizine"

This remedy is better known as "Suprastinex", "Cesera". This is an excellent drug, which is prescribed for patients suffering from an allergic reaction to pollen. The agent is prescribed in case of seasonal manifestations or all-the-year-round. The drug is in demand for the treatment of conjunctivitis, allergic rhinitis.

It is recommended to take the medicine in the morning or during a meal. The drug should not be combined with alcohol.

Conclusion

Medicines of the new generation are active metabolites of previously used drugs. Undoubtedly, this property makes antihistamines of the 4th generation extremely effective. Medicines in the human body are not metabolized, but they give a long and pronounced result. In contrast to the means of previous generations, such drugs do not have a harmful effect on the liver.