Tablets "Midokalm"

Tablets "Midokalm" are covered with a white film shell, have a round biconvex form, have a weak specific odor. On one side there is an engraving "50" or "150", on the cross-section two layers are seen.

One tablet "Midokalm" includes Tolperisone hydrochloride as an active ingredient. Auxiliary components: lactose monohydrate, anhydrous colloidal silicon, talc, monohydrate of citric acid, microcrystalline cellulose, stearin, corn starch, hydroxypropylmethylcellulose 2910, macrogol 6000, titanium dioxide.

Tablets "Midokalm" refer to the clinical and pharmacological group of muscle relaxants of central action.

The mechanism of drug exposure remains unclear until the end. Tablets "Midokalm" have a local anesthetic, membrane-stabilizing effect. The medication is able to inhibit the conductivity of neuronal impulses of motor and afferent fibers of the primary. This provokes blocking of polysynaptic and monosynaptic reflexes in the spinal cord.

The ability of the drug to secondary inhibition of mediator release is likely. In addition, the drug eliminates the ease of excitation in the reticulospinal tract. The use of "Midokalma" contributes to the enhancement of peripheral blood flow regardless of the effect of the central nervous system. With the development of this effect, the value has a weak adrenoblocking as well as antispasmodic effect of tolperisone.

There is a good absorption from the digestive tract after ingestion. The active ingredient in the kidneys and liver is metabolized, the excretion occurs in the form of metabolites by the kidneys.

"Midokalm" tablets. Instructions. Indication.

The medication is prescribed for degenerative and organic neurological diseases, accompanied by increased tonus in the striated muscles (multiple sclerosis, encephalomyelitis, muscle contractures, pyramidal pathway damage, muscle rigidity, consequences of ONMI - acute circulatory disorders in the brain, spinal automatism). The drug is also indicated as a treatment in the recovery period after traumatological and orthopedic interventions, with obliterating vascular pathologies as part of complex therapy, infantile cerebral palsy. In addition, the medication is prescribed for muscle spasms, encephalopathy with muscular dystonia, with hypertension.

"Midokalm" tablets. Instructions for use.

Dosage is established depending on the symptoms and the tolerability of the drug individually.

Patients from one to six years of age, the dose of the drug is calculated in accordance with the body weight (five milligrams per kilogram). Three appointments are prescribed throughout the day.

Patients from seven years to fourteen daily dosage of two to four milligrams per kilogram of body weight. Recommended three times a day.

Side effects may be vomiting, nausea, a feeling of discomfort in the abdominal area, anaphylactic shock, itching, dyspnoea, maculopapular rashes, erythema.

Contraindications to the appointment and reception of tablets "Midokalm" are:

- age to a year;

- Myasthenia gravis;

- hypersensitivity (intolerance) to the drug.

The use of the drug during pregnancy and breastfeeding is allowed in cases where the potential risk to the child is lower than the intended benefit to the mother.

For children, recommended to receive "Midokalm" in tableted form 50 milligrams.

The use of the drug does not affect the ability to control the mechanisms and driving of vehicles, the concentration of attention and the manifestation of the speed of the psychomotor reaction.

There is no evidence of an overdose of the drug.