Preparation "Sirdalud", instructions for use

The drug "Sirdalud" (Sirdalud) is produced in tablets containing four milligrams of active substance, in blisters for thirty pieces.

Pharmacological effects of the drug "Sirdalud" instructions for use describes as follows:

The active substance of this drug is tizanidine, which is a muscle relaxant with a central effect that affects the musculature of the skeleton. It also has a moderate central anesthetic effect.

The use of the drug is justified in acute and chronic spastic pathologies of both central and spinal genesis. Thanks to means "Sirdalud" increases the force of arbitrary contractions of the muscles of the skeleton and reduces spasms, clonic convulsions. Absorption of the drug "Sirdalud" occurs quickly, almost completely. The maximum concentration in the blood is reached within one hour after administration. The average bioavailability index is thirty-four percent. The half-life of the drug is on average from two to four hours. It is excreted through the kidneys (up to seventy percent), as metabolites and only two as much as seven tenths of a percent in unchanged form. Eating together with taking this medication does not affect its pharmacokinetics.

The drug is Sirdalud. Indications for use:

Skeletal musculoskeletal spasms, which are caused by neurological diseases, such as degenerative spinal cord pathology, chronic myelopathy, cerebral palsy, cerebral palsy. Also, with painful muscular spasms accompanying the static and functional pathologies of the spine (with cervical and radicular syndromes), postoperative period after operations for intervertebral herniation of the hip joint osteoarthrosis, and the like.

The method of application for the preparation "Sirdalud" instructions for use gives the following:

Doses are selected by the attending physician on an individual basis, based on the reaction to the drug in the patient and the clinical picture of the disease. The initial volume is no more than six milligrams per day. It is divided into three doses, in three to seven days it can be increased by two to four milligrams.

Usually the therapeutic dose becomes optimal, starting from twelve to twenty-four milligrams per day, divided into three to four doses, at an equal time. Exceed the dosage of the drug "Sirdalud" instructions for use within a higher than thirty-six milligrams per day, does not recommend. In the case of the treatment of painful muscle spasms , the Sirdalud remedy is applied two to four milligrams three times a day. In the case of severe spasms, an additional intake of up to four milligrams of the drug is allowed for the night.

For the treatment of elderly patients with Sirdalud's medication, the instruction manual recommends careful medical supervision, since there is very limited clinical experience in treating this category.

In pediatrics, the use is not recommended, since experience in the treatment of this drug in children is inadequate.

In case of renal insufficiency, the preparation of "Sirdalud" recommends the use of the instruction, starting from two milligrams per day at a time. Then gradually increase the dosage, taking into account the tolerability and effectiveness.

The drug is Sirdalud. Description of side effects:

Seldom there are disturbances from the digestive tract, drowsiness, weakness, a slight hypotension, dry mouth, dizziness.

Contraindications to the use of the medication "Sirdalud" are the following:

Severe dysfunction of the liver, hypersensitivity to the components of the drug, a possible combination of tizanidine with fluvoxamine.