"Movinase": instructions for use, analogues

The "Movinase" tablets, the instruction for use in details, tells about the doses and the method of taking the drug, they have the ability to penetrate into the inflamed parts of tissues, lyse the dead cells, and also the products of their decomposition. Reduce hyperemia and increase the penetration of antibiotics. The drug reduces the viscosity of saliva and reduces discharge from the nasal cavity.

Composition and form of the drug

Before using the "Movinase" tablets, the instructions for use must be studied. The drug contains the active substance - serratiopeptidase.

It is produced in tablets with an enteric-dissolving coating of 10 and 20 mg, which are packaged in aluminum blisters of ten. The carton contains thirty tablets and instructions.

Pharmacological action of the drug

The drug "Movinase" (the instruction on application is attached to the tablets) is a proteolytic enzyme obtained from the bacterium Serratia E15, which is located in the human intestine. Has fibrinolytic, anti-edematous and anti-inflammatory properties. Not only reduces inflammation, but also reduces the severity of the pain syndrome, inhibits and releases amines of pain from tissues that are inflamed.

Serratiopeptidase combines in a 1: 1 ratio with blood α-2-macroglobulin and masks their antigenicity, but at the same time continues to retain enzymatic activity. The active substance gradually passes into the exudate at the site of the inflammatory process, lowering its level in the blood. Reduces dilatation of capillaries, conducts control by hydrolysis of serotonin, histamine and bradykinin. It inhibits plasmin inhibitors, develops fibrinolytic activity. Due to the proteolysis of the sputum proteins, rheological qualities are restored, which contributes to its rapid separation.

The enzymatic activity of the drug is ten times greater than that of α-chymotrypsin. In the field of chronic inflammation, the active substance reduces the mediators of inflammation and pain, hydrolyzes fibrin, prevents spikes, reduces microcirculation in the inflammatory focus, due to increased bioavailability of drugs.

"Movinase" does not affect the protein of animal origin, for example, albumin, α- and γ-globulin. The drug does not cleave fibrinogen and, therefore, does not affect the coagulability of the blood.

In general, "Movinase" reduces the inflammatory nature of tissues, reduces edema, increases the effects of NSAIDs and antibiotics. Has an enteric-soluble coating, which has a high degree of protection.

The medicine passes through the gastric organ in an unchanged form and is absorbed in the intestinal medium. The maximum concentration of the active substance in the blood is reached in an hour. It leaves the body with bile, and an insignificant part with urine.

Indications for use

The drug "Movinase" (instructions for use strongly advises before using tablets to consult a doctor) is used in surgery. Here it is used for stretching and rupturing of ligaments, as well as for fractures and dislocations. He treats edema arising after surgery.

Assign a medicine for diseases of the upper respiratory tract. It reduces the viscosity of sputum and promotes its rapid separation. Doctors prescribe the drug for ENT diseases for more effective disposal of secretions from the paranasal sinuses. Indications for use are acute dermatoses with inflammatory foci. Use the drug in obstetrics and gynecology to treat hematomas and eliminate stagnation in the mammary glands.

"Movinase-20": instructions for use

Tablets are used orally. They drink without chewing, washing with water.

"Movinase-10" (instructions for use warns against contraindications and possible side effects) is prescribed to adults in a dosage of 10-20 mg once a day after meals. The maximum daily dosage should not exceed a dose of 30 mg.

The duration of the course of taking the tablets is regulated by the doctor depending on the patient's condition and the course of the illness.

Contraindications for use

The agent "Movinase" (20 mg), the instruction for use introduces the rules of storage of the drug, despite its effectiveness, has contraindications. These include hypersensitivity to serratiopeptidase and additional components of the drug. The prohibition against eating is caused by diseases associated with poor blood coagulability.

In some cases, the use of the drug patients worried about side effects. Among them, vomiting, diarrhea, anorexia, nausea, discomfort in the epigastric zone. Sometimes there was bleeding from the nose, the appearance of sputum with blood, an allergy, a rash, eosinophilic pneumonia in the acute stage.

If there are negative reactions, the medication should be stopped and consulted by the treating physician to review the therapeutic purpose.

special instructions

Warns what affects the coagulability of the tablet "Movinase" tablets, instructions for use. Reviews say that the drug is highly effective and quickly removes swelling and inflammation. It should be taken with extreme caution by patients with increased bleeding threat and those who have blood clotting problems and who use anticoagulants.

The drug should be administered with extreme caution to patients with liver and kidney disease.

Do not take pills for pregnant and lactating women, as there are no clinical data on the use of the drug during this period.

Do not give pills to children, since there is no data on the safety and efficacy of the drug in this category of patients.

"Movinase" does not affect the ability to make decisions and the speed of response when driving a vehicle and similar vehicles that require increased concentration of attention.

Joint use with anticoagulants increases the influence of the latter on the body. Promotes faster penetration into the inflamed environment of antibiotics and NSAIDs.

When an overdose occurs nausea, anorexia, vomiting, bleeding, there is blood in the sputum.

It advises to conduct only symptomatic treatment for an overdose of the drug "Movinase" instructions for use.

Analogues

If the drug has caused negative phenomena, then it can be replaced by another with a similar effect. Thus, the direct analogues of "Movinase" include "Serox" and "Serrata". To medicines with a similar effect, but having in the composition of another active substance should be attributed: "Wobenzym", "Fibrinase-10", "Fibrinase-20", "Phlogenzyme".