"Levofloxacin": review, description of the drug, instructions for use

Antimicrobial agents can be prescribed for various diseases. However, before using such medications, you should always contact a doctor. After all, to assign a medication you need to first identify the causative agent of the infection, and only then choose the appropriate medicine.

One of the most effective and effective antibacterial drugs for today is "Levofloxacin". You will be able to find consumer feedback on this medication at the end of the article. Also, it will provide information on the form in which the medicine is made, how much it costs, what are its properties and so on.

Form, description, packaging and composition of antibiotic

You can buy this medication in the following forms:

• Oral Levofloxacin (tablets). They have a film membrane, a yellow color, a round biconvex shape. Two layers are visible on the cross-section of this medication. The active ingredient of the drug is levofloxacin hemihydrate, and auxiliary substances are hypromellose, microcrystalline cellulose, calcium stearate and impellose. In the sale of tablets come in contour packs and packs of cardboard.
• Local remedy for eyes "Levofloxacin". Drops that are homogeneous, transparent and practically not colored, are available in vials provided with a lid in the form of a dropper. The active substance of this drug is levofloxacin. As additional components, sodium chlorine, deionized water and disodium edetate dihydrate are used.
• A solution of "Levofloxacin". Consumer reviews say that this form of the drug goes on sale in bottles with a volume of 100 milliliters. The active ingredient of this drug is levofloxacin. It also includes auxiliary components.

Pharmacodynamics of the drug

What is Levofloxacin? According to the instructions, this is an antibiotic that belongs to the group of fluoroquinolones. Its active ingredient has a bactericidal effect. After using the medicament, enzymes responsible for replicating DNA in bacterial cells are almost immediately inhibited.

The drug in question is active against the causative agents of respiratory infection. It effectively treats diseases caused by penicillin-resistant strains of pneumococcus, Escherichia coli, Enterobacter spp., Citobacter spp. And Klebsiella spp. In addition, this medication is effective for tuberculosis and sinusitis.

Pharmacokinetics of the drug

When taken on an empty stomach, the bioavailability of the drug is 100 percent. If the medicine "Levofloxacin" (500 mg) is used in the process of food intake, then its maximum concentration in the blood is reached 60 minutes later.

According to the instructions, this drug is distributed in plasma and interstitial fluid, and also accumulates in various tissues. Splitting of the drug occurs in an amount of 5 percent. It is excreted by the kidneys to 85 percent.

The half-life of the drug is 6 hours. At the same time its post-antibiotic action lasts 3 times longer.

Indications for antibiotic use

The antibiotic "Levofloxacin", whose price is about 250-300 rubles, is prescribed for infectious and inflammatory diseases, provoked by microorganisms sensitive to it. Thus, the tablets in question are used:

• With prostatitis;
• Intra-abdominal infection;
• Chronic bronchitis (exacerbation);
• Sinusitis acute;
• Complicated and uncomplicated urinary tract infections;
• Infections of soft tissues and skin;
• Community-acquired pneumonia;
• Septicemia or bacteremia.

Solution for infusion is used for infections of the urinary tract, lower respiratory tract, kidneys, soft tissues, skin, ENT organs and genital organs.

As for eye drops, they are used for superficial infections of bacterial origin.

Contraindications to taking medication

This drug has the following prohibitions to use:

• epilepsy;
• Underage age;
• pregnancy;
• Kidney failure;
• Adverse reactions to drug substances;
• Lesions of tendons during treatment with quinolones;
• lactation.

With extreme caution antibiotic is recommended for elderly people and those with a deficiency of glucose-6-phosphate dehydrogenase.

How to use the drug "Levofloxacin"?

Consumer feedback about this medicine is positive. We will introduce them at the very end of the article.

Features of the use of drops, tablets and solution for infusions differ. Therefore, before using them, we recommend that you consult a doctor.

Tablets "Levofloxacin" are taken twice a day, before meals. They are swallowed whole or split in half. The duration of treatment with such a drug, as well as its dosage, depends on the severity of the infection and its nature.

A solution for infusions is also administered twice a day. And it must be administered drip (no faster than one hour).

The drug for the treatment of eye diseases is applied only topically. During the first two days, 1-2 drops should be used every two hours. Bury the medicine in the eye can be up to eight times a day.

From the 3rd to the 5th day, make this medication preferably 1-2 drops, four times a day. Thus, the course of treatment with this drug is 5 days.

Adverse events

According to the experts, the drug in question often causes side effects. They can develop from different organs and systems. The most common adverse reactions include the following: increased liver enzyme activity, nausea, redness of the skin, itching, dizziness, loss of appetite, general feeling of weakness, vomiting, stupor, headache, exacerbation of porphyria, insomnia, palpitations, muscle weakness and others.

Consumer feedback on antibiotics

What do consumers say about the drug "Levofloxacin"? Reviews about this medicine can leave everyone. According to the opinion of the patients, this remedy proved to be a very effective and effective medicine that copes well with infectious diseases of the genitourinary, respiratory system, as well as diseases of the visual organs.

A huge disadvantage of this drug is the presence of a large number of adverse reactions. They can occur not only from the reception of tablets, but also from the use of a solution for infusions, as well as drops for the eyes. In this regard, the medicine in question should be used only according to the doctor's prescription and according to strict indications.