The drug "Normase": instructions for use

The drug "Normase" (Normase) is available in the form of a syrup in bottles with a volume of two hundred milliliters.

Pharmacological effects of the drug "Normase" instructions for use describes as follows: it has a laxative effect, based on the difference in osmotic pressure, and reduces the content of ammonium ions in the blood. The active substance of the drug is lactulose, a synthetic substance built from the remains of fructose and galactose. Lactic acid is not affected by hydrochloric acid in the stomach or digestive enzymes, and only in the large intestine begins to decompose under the action of the microflora contained therein. Lactulose is able to increase the osmotic pressure in the large intestine and transfer the liquid from the blood into the lumen of the large intestine. These actions lead to an increase in the volume of feces, their softening and, as a consequence, stimulation of intestinal peristalsis. In addition, due to the creation of an acidic environment in the large intestine , the development and growth of pathogenic microflora is inhibited, and for favorable microflora, on the contrary, more favorable conditions are created. Also increases due to lactulose secretion of bile, the content of toxins decreases. The therapeutic effect of the drug begins after 24 hours - two after oral administration. Most of the drug "Normase" stands out with feces, and only eight percent in the form of metabolites with urine.

Indications for prescription of medicinal substance "Normase" the instruction on application gives such: constipations, including chronic, children's, at pregnant women and persons of advanced age. Hepatic encephalopathy, treatment and prevention of precoma and coma in this condition, violations of the flora in the large intestine, even with the appearance of such pathogenic microflora as salmonella. Dysbacteriosis, which occurs with antibiotic therapy, nutritional errors. In the preoperative period and after surgery, with the aim of regulating the stool with hemorrhoids, with the syndrome of putrefactive dyspepsia in young children, including dyspepsia, which appeared due to food poisoning. The drug "Normase" is used for the complex treatment of vaginal candidiasis and vaginal dysbacteriosis, osteoporosis (as it stimulates the adsorption of minerals in the large intestine, its proximal part).

Method of taking the drug "Normase" instructions for use describes this: take it orally, after eating. Adults with constipation appoint in the first three days of fifteen to forty milliliters per day, and then make the transition to a maintenance dosage - from ten to twenty-five milliliters per day. Children over the age of six, as well as adolescents in the first three days - fifteen milliliters per day, maintaining a dosage - ten milliliters. Children between the ages of one to six - from five to ten milliliters per day. Children under the age of one year are prescribed five milliliters per day.

The course of treatment for the drug "Normase" instructions for use provides for four weeks and up to three to four months, which depends on the peculiarities of the pathological process in each patient individually. In the case of hepatic precommission, coma, or encephalopathy, as well as an increase in ammonia in the blood, an initial dose of thirty to six milliliters of the drug is given three times a day. Subsequently, the dose is adjusted until reaching a soft stool frequency two to three times a day. The course of therapy usually lasts a minimum of three months. In the postoperative period, the drug "Normase" is prescribed after eighteen hours from the end of the operation by a course of three to five days. For adults, it is prescribed from ten to thirty milliliters three times a day. For children older than a year - from five to ten milliliters per day, for children up to a year - five milliliters twice - three times a day.

The drug "Normase" with breast-feeding is allowed.