Glutoxim: instructions for use, reviews

What is the purpose of the drug Glutoxim? Instructions for using this tool will be provided in the article. Also you will learn about what contraindications this drug has, in what forms it is produced, how much it costs, whether it has analogues and so on.

Form of release of the medicine

In what form is the preparation "Glutoxim" produced? This drug can be found in the pharmacy only in the form of a clear solution, which is for injection. It has no odor, no color, and is packaged in ampoules of one or two mg.

Composition of the medicament

The drug "Glutoxim", the instruction for which is provided in the kit, contains an active component such as bis- (gamma-L-glutamyl) -L-cysteinyl-bis-glycine disodium salt. In addition, the medicament includes also auxiliary ingredients in the form of sodium acetate, acetic acid and water for injection. In fact, the said preparation is a mixture of disodium salts and three different amino acids (cysteine, glycine and glutamine).

Concentration of the agent

The concentration of those or components in the drug may be different.

• Glutoxim solution 1% contains 10 milliliters of active substance.
• A 0.5% solution contains 5 milliliters of the active ingredient.
• The Glutoxim solution 3% contains 30 milliliters of the active substance.

When the ampoule is opened from the medicine, a light aroma of acetic acid can emerge. You can buy this medication in a cardboard box with 10 or 5 ampoules inside.

Pharmacological properties of medicament

The drug "Glutoxim" is an immunomodulating agent that is intended to strengthen the immunity of a person. It quickly restores cellular receptors, as well as their sensitivity to regulatory elements. Moreover, this drug produces a pronounced cytotrophic effect.

After using the drug, he is able to increase the production of all kinds of cells that are responsible for a nonspecific immune response. In addition, the drug accelerates the formation of lymphocytes, erythrocytes, granulocytes (monocytes) and hematopoiesis in the bone marrow.

What other properties does the drug Glutoxim have? Experts' reviews contain a lot of information that this drug is able to significantly improve the patient's condition. After all, it easily activates the processes of phagocytosis and tissue macrophages. The drug stabilizes the blood formula, and also increases the number of cells in it, stimulates the signal systems that are responsible for the formation of the immune response.

This medication is able to initiate the production of cytokines (i.e., tissue hormones), interferons, tumor necrosis factors designed to fight the formation of cancer cells in the human body, and erythropoietin hormones that accelerate the production of red blood cells in the bone marrow.

Pharmacokinetics of the drug

After intramuscular, intravenous or subcutaneous administration, the bioavailability of the drug reaches 90 percent. That is, 10 percent of the active component is not absorbed by the human body, but is output outside. There is a linear dependence of the concentration of the drug in the blood on the concentration of the solution used.

When intramuscular injection of the drug, its maximum concentration is achieved in seven to ten minutes, and with intravenous - in two to five minutes.

This drug is metabolized in the organs and tissues of the body, and the products of its decay are excreted exclusively through the kidneys.

Indications for use of the medicinal product

In what cases is the patient prescribed a drug "Glutoxim"? Instructions for use of this tool contain a long list of indications for its use. Let us consider them in more detail.

• This drug is often used to treat and prevent secondary immunodeficiency conditions. As a rule, they are caused by various infections, as well as chemical or radiation factors.
• Doctors can prescribe the drug "Glutoxim" to stimulate the bone marrow. After all, it is the active component that enters into it that takes direct part in supporting the normal formula of human blood.
• If the patient is diagnosed with infectious liver diseases (eg, hepatitis B, C or D), then such a drug is used as a good hepatoprotector (liver protector).
• In the event that the patient has chronic obstructive pulmonary disease, the drug Glutoxim is used to enhance the effect of taking hormonal drugs and antibiotics.

What other deviations can cause the doctor to prescribe a drug called Glutoxim? The instruction says that indications for the use of the medicine can be the following pathological conditions:

• After the operation, the agent is used to prevent inflammation.
• During the treatment of tuberculosis, this drug is very effective in disseminated form of the disease, as well as with reduced sensitivity of the pathogen to antibiotic agents and stimulation of the patient's immune system.
• Very often, the drug "Glutoxim" is used to prevent exacerbations of hepatitis. As a rule, this occurs during antituberculous treatment.
• This drug is an effective tool that is actively used to combat intoxication. This is why it can be prescribed to reduce the toxic effects of chemotherapy on the liver and other internal organs.
• During the antitumor treatment, the medication is used to restore the hematopoietic function of the bone marrow. Its use helps to overcome such side effects from treatment as high fatigue, anemia, decreased appetite and increased sensitivity to pain.

One can not help saying that in rare cases a patient can be prescribed a medicine called Glutoxim in psoriasis. Reviews about this drug are mostly positive.

Contraindications to the use of medicament

In what cases is it not recommended to use the drug Glutoxim? The instruction for the use of this remedy states that it can not be prescribed if the patient has an individual intolerance to the components of the medication.

It should also be said that studies on the reception of this drug during lactation and pregnancy have not been conducted. That's why in such situations, women are advised not to use it.

"Glutoxim" medication: instructions for use

For adults, the dosage of this remedy should be from 5 to 40 milligrams daily. Intramuscular, subcutaneous and intravenous routes of administration can be used. Dosage in each case is chosen exclusively by the doctor.

• To combat adverse environmental factors, as well as for preventive measures after surgical intervention, the drug is prescribed in a dosage of 5-10 milligrams every day for 2-4 weeks.
• During the treatment of inflammation of the urogenital system and the lungs, as well as allergic reactions, the drug is used in an amount of 5-40 milligrams per day. The course of treatment is 2-3 weeks.
• With antituberculous treatment, the medication is used at a dosage of 60 milligrams a day in two divided doses. Duration of therapy is 2 months. After the disease goes into the productive phase, a dose of 10-20 milligrams is prescribed twice a day three times a week. After the course of therapy, you should take a break for 2-6 months.
• In psoriasis, a patient may be prescribed 10 milligrams of the drug (intramuscularly). Treatment should be done every day for 14 days. After that, for 35 days, the medication is used two more times a week in a dosage of 10 milligrams. If uncomplicated psoriasis is administered, the drug is prescribed at a dose of 10 milligrams per day for 10 days.
• When chemotherapy and antitoxic accompaniment of radiation therapy, the drug is used subcutaneously in an amount of 60 milligrams. In this case, the drug is prescribed 2 hours before the procedure, and then twice a week in a similar dosage. The drug is used during each chemotherapy.
• For the prevention of infectious diseases, the drug is prescribed a two-week course in an amount of 5-10 milligrams.

It should also be recalled that for intravenous administration, a 5% glucose solution or physiological saline solution should be used.

Features of the drug

What do patients think about the drug Glutoxim? Their opinions vary. Some men who have been prescribed this medication for the treatment of kidney disease, note that it improves the erection. Specialists have proven that this tool increases the number of live sperm in the sperm, and also reduces the severity of side effects after the use of antibiotics. In addition, this medicine is able to increase the effectiveness of antibacterial drugs that are related to the quinolone series ("Ofloxacin", "Oxolinic acid", "Norfloxacin" and "Cyclofloxacin").

This drug accelerates remission in the treatment of chronic kidney disease. Its use significantly reduces the frequency of relapses, until their complete disappearance.

According to experts' reviews, the drug Glutoxim is very effective in the treatment of chronic prostatitis, as well as infectious diseases that are sexually transmitted.

Side effects of Glutoxim

The use of this drug must be controlled by a doctor, despite the fact that the drug does not have a lot of side effects. With intramuscular or subcutaneous injection, the patient may experience an increase in body temperature to 37.5 degrees. But this is only if the patient has an individual intolerance of the constituent components.

Use of medicines for children

Can I make injections of Glutoxim to children? Of course, yes. But this is only if other drugs have been ineffective.

As for the scope of application of the drug Glutoxim, the dosage for children is calculated based on weight (2.5-5 milligrams per kilogram). In this case, the drug can be administered intramuscularly, intravenously or subcutaneously.

During the treatment of kidney disease in young children and adolescents, the use of this drug is associated with a reduced effectiveness of antibiotic and hormone treatment. Medical practice shows that the use of this medicine speeds up the onset of remission, and also improves the overall condition of patients, without affecting the blood formula.

Interaction with alcoholic beverages and other preparations

In addition to enhancing the effect of antibiotics of the quinolone series, no other interactions with drugs have been identified. With regard to alcoholic beverages, then, given hepatoprotective properties, this medication reduces the negative impact of alcohol on the kidneys and liver. In doing so, it accelerates the breakdown of alcohol in the blood.

Analogues of the drug, price

How much does this medicine cost? It should be noted that the price of this medication is quite high. So, for 5 ampoules of a 1% solution (2 ml) you will have to pay about 1600 rubles. As for the 3% solution, it costs even more - about 2000 rubles.

What to do if you do not have enough money to purchase the drug Glutoxim? Analogues can be much cheaper. Among such drugs, we can mention the following: Vironel, Amiksin IS, Biolakekin, Lavomax, Avonex, Anaferon, Alfiron, Galavit, Viferon, Echinacea compositum, Immunoflazid, Azoximer Bromide, Septiline, Roncoleukin, Protfenoloside, Granocyte, Imunorm, and others.

It should be specially emphasized that each of the medicines presented has its own peculiarities of use. However, they all have about the same effect on the human body.

Testimonials of experts about the drug

According to the doctors' reviews, during the chemotherapy this medicine is able to quickly remove all toxins from the body, which directly affects the general condition of the patients. In addition, some experts say that the drug "Glutoxim" is very helpful in the treatment of infectious diseases, especially with bronchitis. This immunomodulator works effectively and very quickly, shortening the duration of therapy by about a third.

Patient Reviews

Patients who have ever used this medication after chemotherapy note that, compared to the first course, when this remedy was not yet prescribed, the condition became more comfortable. At the same time, the taste in the mouth and dryness of the mucous membranes completely disappeared. Also, the patients noticeably improved their sleep, the usual anxiety condition, which occurred every time after the completion of the chemotherapy procedure, was gone.

Those patients who received the drug Glutoxim for the treatment of prostate cancer, note an impressionable result. The growth of the neoplasm slowed, and the inflammation began to decline.

Patients with a diagnosis of "pulmonary tuberculosis" also talk about the effectiveness of the drug. According to their reviews, the treatment of the disease passes quickly and comfortably. In patients, the normal blood formula is restored, signs of intoxication disappear, and sleep improves, and unpleasant bitterness in the mouth, dry mucous membranes disappear.

Additional information about the drug

Currently, the study of the effect of the drug on the human body continues. The instructions, which are attached to the medicine, give the most studied methods of taking the medicine. There are data on the effectiveness of its use in the treatment of infectious diseases, including those that are sexually transmitted, as well as various hepatitis, tumors and other abnormalities.

Shelf life of the preparation and its storage conditions

Where and how to store the drug Glutoxim? According to the instructions, this drug should be placed in a dark place, where the direct rays of the sun do not fall. The storage temperature should not be more than 25 degrees Celsius. Also, the drug is not recommended to be placed where it can reach young children.

Shelf life of the drug "Glutoxim" is three years. The use of the drug after this period is strictly prohibited.