"Drotaverin" from what? "Drotaverin" is "No-shpa"?

For a long time, the drug "Drotaverin" is in high demand among patients. Effective work of the drug, proven during multiple clinical trials, allows it to be used as a quick-acting and easily accessible drug. "Drotaverin" - injections or pills - can be used both once, and in a complex course of therapy for many diseases.

Creature

In 1961, a derivative of "Papaverin", a drug called Drotaverin, was developed. In the course of clinical and pharmacological studies, the more effective work of the drug "Drotaverin" in relation to its predecessor was proved.

The drug "Drotaverin" with its main metabolites is a powerful selective inhibitor of cells of smooth muscle tissue, due to this not only gives an anesthetic effect, but also achieves a reduction in inflammation and edema of damaged tissues, on the whole receiving a positive effect on the functioning of the body. Many patients ask themselves the question: "Drotaverin tablets are No-shpa?" Yes, No-shpa is an analogue of it, and Drotaverin can also be replaced with many other similar antispasmodic medications.

Drotaverin: what helps

Elimination of spasm is the main function of the drug, but since pain is just a symptom characterized by physiological and pathological contraction of the muscles accompanied by certain diseases, it means that the drug "Drotaverin" is prescribed together with other medications. Deterioration of blood circulation of the damaged area can serve as the beginning of the pathological process.

Medical practice has a number of cases in which the use of Drotaverin is required, but the main areas are:

• As a preparatory tool for patients sent to various procedures, for example, on the catheterization of the ureters.
• As symptomatic therapy, when pain is the main characteristic accompanying manifestation of the disease, but does not play a leading role in its pathogenesis.

How the drug works

The therapeutic effectiveness of Drotaverin is based on the effect on the mechanisms of muscle contraction. When the cells of the smooth muscle relax, the tension (tone) of the walls of the sexual female organ decreases, the pain in menstruation is significantly weakened or completely eliminated. Thanks to the successful relief of pain, the blood supply to the walls of the organ improves.

Unlike other drugs-analgesics, "Drotaverin" does not erase the symptoms of the disease. The drug "Drotaverin" prescription for its purchase does not require, it can be presented in several forms, the appointment of which should be decided by the attending physician:

• Ampoules of 2 ml contain 40 mg of the active substance "Drotaverina".
• Tablets with a dosage of 40 mg of active ingredient.
• Forte tablets with increased dosing of 80 mg of the substance.

Drotaverin: the main directions of the drug

In diseases of the gastrointestinal tract, the drug "Drotaverin" influences the organism quite positively, which weakens the smooth muscle and relieves spasms. The agent can greatly help with the following ailments:

• Colitis.
• Pancreatitis.
• Dysfunction of the sphincter of Oddi.
• Irritable bowel syndrome.
• Not ulcerative indigestion.
• Peptic ulcers of the stomach and duodenum.
• Papillitis.
• Cholangitis.
• Pericholecystitis.
• Cholecystitis.
• Cholelithiasis.

The results of the research showed ...

The drug "Drotaverin": from what it is so useful, and what is its advantage among other drugs? During testing of the drug and clinical studies aimed at studying the effect of the drug on patients diagnosed with stenosis of the sphincter of Oddi, a significant weakening of the syndrome in 60% of all subjects was noted. In this case, the more effective effect of the drug "drotaverin" on other analgesics was proved.

In patients with intestinal disorders, including irritable bowel syndrome, during the trial of the drug, the positive dynamics of the effect of the drug was similarly observed. 62 patients with constipation and IBS participated in the study. Every day for 2 weeks the subjects marked their complaints before the beginning of the treatment, then within 2 months taking the Drotaverin tablet 3 times a day. With active treatment, there was a decrease in abdominal pain in 47% of patients. When taking Drotaverin, other symptoms of GI dysfunction decreased.

The effect of the drug "Drotaverin" on the systems and organs of the human body

As mentioned above, the drug "Drotaverin" from which it does not help, it can be used for a variety of diseases.

1. Has a moderate sedative, antiischemic and coronary expansive action. Has a beneficial difference from the "Papaverin", as the latter can reduce the tone, contributing to lowering blood pressure, dizziness and hyperventilation of the lungs.
2. It increases blood flow and greatly reduces the resistance of the vascular system.
3. Does not affect the heart rate index, practically does not change blood pressure. Moderate hypotension can persist for half an hour after intake, no more.
4. It does not affect the autonomic nervous system. In connection with the direct effect of the drug "Drotaverin" on smooth muscle can be used as an anesthetic in cases where the use of holinoblokatorov is contraindicated - with hypertrophy or glaucoma of the prostate gland.
5. After internal administration, the drug begins to act after 2-4 minutes, the maximum effect of the drug is observed in half an hour.
6. Also, the drug "Drotaverin" is an active element in chronic lung diseases, hemodynamics, favorably affects the normalization of the functional state of myocardial contractility.
7. It is able to improve the blood supply of tissues, since it has a vasodilating effect.

If there is no analogue of Drotaverin in the pharmacy, the following can be chosen: Spacovine, Sporaverin, Spazmonet Forte, Spazmol, Ple-Spa, Nosh-bras, No-shpa.

Side effects of the drug

In the cardiovascular system:

• Enhanced palpitations.
• Feeling of heat.
• With intravenous administration, blood pressure may drop.
• Development of AV blockade.
• Arrhythmia.

In the respiratory system:

• With intravenous injection, the respiratory center is depressed.

Among others it is possible to note:

• Intensified sweating.
• Dizziness.

Who should not take it

The drug "Drotaverin", from which it just does not help, but in some cases the doctor can prohibit its reception. Contraindications to the use of the drug "Drotaverin" are the period of pregnancy and lactation. Also, the drug is canceled if there is an increased sensitivity to the components of the formulation.

The presence of any action of the drug on a pregnant woman was not established. The administration of Drotaverin is possible only after a medical evaluation of the potential risk to the fetus and the positive effect for the mother. Clinical studies in the lactation period have not been conducted, so the prescription of the medication during breastfeeding is undesirable.

Overdose

When taking the drug above the established rate, an overdose may occur, accompanied by the following symptoms:

• Heart failure.
• Paralysis of the respiratory center.
• AV blockade.
• Vascular insufficiency.
• Inhibition of respiration.
• Nausea.
• Vomiting.
• Increased sweating.
• Pale skin.

If any of these symptoms or a part of them are found, the doctor should be called immediately.

Can it be assigned to children

A single dose for oral administration is 10-20 mg for children younger than 6 years, 20 mg at 6-12 years, with a frequency of 1-2 times per day.

With increased caution should take the drug with arterial hypotension. During intravenous administration of the substance, the patient must always be in a prone position, because of the danger of collapse.

Other benefits of taking the drug

The advantage can be considered that when taking the medication internally at a therapeutic dose, it is in no way an obstacle to driving or any other potentially dangerous activity. However, after intravenous administration, it is still recommended not to drive the vehicle for a while, for about 1 hour.

The announced research data and the doctors' own observations prove that the drug "Drotaverin" is a highly effective antispasmodic agent, suitable for extensive use in various therapies. Depending on the dosage and the form of release of the drug "Drotaverin" the price can range from 10 to 50 rubles.