Candles "Neotrizol": user manual, reviews

How to use the medicine "Neotrizol" (candles)? Instructions for the use of these suppositories will be presented below. Also from the materials of this article you will learn about what helps this drug, what features are inherent in it, what patients are saying about it and whether it has side effects.

Packaging, composition

Candles "Neotrizol", the instruction of which is enclosed in a cardboard box, contain in itself such effective components as miconazole nitrate, ornidazole, neomycin sulfate and prednisolone. They are produced in blisters for 8 pieces.

Pharmacodynamics of the preparation

What is the mechanism of the Neotrizole drug? Instructions for use say that this is an antibacterial agent that has an antifungal effect. It shows active action against gram-negative bacteria and Gram-positive microorganisms, penetrates into their structure and blocks the synthesis of proteins.

Properties of the preparation

The effectiveness of this drug is due to its composition.

Neomycin is an antibiotic substance that belongs to the aminoglycoside group. It is active against gram-negative bacteria, and is also very effective against gram-positive microorganisms.

After applying the drug, neomycin immediately penetrates into the structure of bacterial cells, and then blocks the synthesis of proteins, which are extremely necessary for their survival.

Miconazole is an antifungal agent intended for topical therapy of vulvovaginal candidiasis. This element effectively manifests itself in relation to Candida vulvovaginalis.

As for prednisolone, this is a synthetic SCS. It is used to reduce the severity of signs of various inflammations. This element is able to inhibit the production and release of inflammatory mediators. It also slows proliferative processes and significantly reduces the likelihood of scarring.

Pharmacokinetics

What kinetic parameters are inherent in Neotrizol? The guideline says that with local use of ornidazole, its concentration in the tissues of the vagina significantly exceeds the concentration achieved by intravenous administration and oral intake.

Systemic effects of this drug does not have. After using candles, neomycin penetrates into the structure of the bacterial cell. This is due to the increased production of abnormal proteins. They block the production of bacterial elements, which are extremely necessary for their survival.

With topical application of the drug, its high activity was noted. Miconazole has a toxic and selective effect on yeast-like fungi of the genus Candida.

With regard to prednisolone, then with local use, it reduces the severity of signs of the inflammatory process, including hyperemia. His systemic effect was not fixed.

Indications for use

What is the purpose of the medicine "Neotrizol" (candles)? Instructions for use say that this drug is actively used to treat such gynecological diseases as:

• Vaginitis of different etiology;
• Bacterial vaginosis;
• Mixed infections, including anaerobic infections, trichomonads, gardnerella, yeast-like fungi, leptotriks.

With a preventive purpose, the drug in question is used before surgery for gynecological diseases, as well as for the sanitation of the vagina before abortion or childbirth, before and after using intrauterine contraceptives, diathermocoagulation of cervical erosion, and before intrauterine tests.

Contraindications

What are the contraindications for Neotrizol? The instruction says that there are not very many prohibitions to use this tool. It is not prescribed only if the patient is sensitive to the drugs.

Candles "Neotrizol": instruction

The doctors' comments about this drug report that it should be injected deep into the vagina in the amount of one candle, at night. After this procedure, the patient should be in a lying position for about ¼ hours (can be a little longer).

The average duration of therapy with this drug is 8 days. During menstruation, treatment is not interrupted.

It should also be noted that after the disappearance of all symptoms of the disease, the use of vaginal tablets should continue in the same dosage (until the entire course is completed).

If after 8 days the signs of the disease have not disappeared, then it is necessary to turn to the gynecologist. After examination and examination, a specialist can prescribe repeated therapy with the same remedy.

How to use Neotrizol for preventive purposes? The instruction says that for the prevention of gynecological diseases this medication is also used for 8 days.

Method of administration

How should I insert the Neotrizal vaginal suppositories? The instruction contains the following guide to action:

• Arrange the vaginal tablet in the attached applicator.
• Immerse the applicator with a tablet in boiled water, the temperature of which is 30-40 degrees (for a few seconds).
• Carefully guide the applicator with the tablet into the vagina (as deep as possible), lying on your back.

After the procedure is carried out, the applicator is removed from the vagina, it is dismantled and thoroughly washed in warm soapy water. The device is then dried at room temperature, reassembled and used for its intended purpose.

Side effects

Does the side effect of Neotrizol? The instruction says that this remedy is not toxic. It does not cause sensitization.

The medication is well tolerated by all patients. Very rarely it can cause spasms and headaches, itching, irritation, burning, hives and rashes on the skin.

It is necessary to stop using candles with increased sensitivity to their components or the occurrence of irritation.

Interaction with other drugs

Clinically significant interactions of Neotrizol with other medications have not been revealed. Systemic absorption of prednisolone should be taken into account when there is a pronounced local inflammatory process.

Special Recommendations

When using systemic corticosteroids, constant monitoring of the patient's condition in case of heart failure, osteoporosis, serious emotional disorders, tuberculosis, diabetes, myopathy, glaucoma, hepatic insufficiency, gastric ulcer, epilepsy, myocardial infarction and hypothyroidism is required.

Despite the fact that the drug "Neotrizol" is used topically, its systemic absorption is possible with inflammation of the vagina.

With special care, vaginal suppositories should be prescribed to people with nonspecific colitis, severe pseudo-paralytic myasthenia gravis, new intestinal anastomoses, and diverticulitis.

Pregnant women, children and lactating mothers are not prescribed this drug.

Reviews about the drug

Most reviews about the candles of Neotrizol are positive. Patients claim that this drug contributes to the rapid treatment of various gynecological diseases. Most often it is prescribed for vaginitis and bacterial vaginosis. Also, this medication effectively treats mixed infections.

Now you know what the vaginal Neotrizol tablets are. Instructions, reviews about them are described in this article. Specialists do not recommend using this medication at their own discretion. It should only be used as directed by a gynecologist.