"Azomeks" (tablets): instructions for use, composition, description, reviews

Problems in the work of the cardiovascular system can hardly be considered a rarity. To date, many people suffer from high blood pressure, which can be a symptom of various diseases. Fortunately, it can be eliminated with the help of medicines.

A fairly good drug for high blood pressure is "Azomex" (tablets). Instructions for use, indications for admission, side effects, prices and opinions of specialists are the main questions that are of interest to every patient. So what is a medicine?

Azomex tablets: a description of the drug

Many people are faced with a diagnosis of "hypertension". And in such cases, doctors recommend the drug "Azomex". The composition and form of release, as well as the properties of the medication - this is what the patients are primarily interested in.

The drug is released in the form of small tablets of white, sometimes yellowish color, placed in blisters of 10 pieces. The main active substance here is S - amlodipine in the form of besilate - one tablet contains 2.5 or 5 mg of this component.

As for the combination of excipients, the preparation also contains magnesium stearate, lactose, colloidal silicon dioxide, microcrystalline cellulose, croscarmellose sodium, and yellow iron oxide.

What are the properties of the medicine?

Many people recommend taking Azomex. What helps it? How exactly affects the body?

The main active component of the drug is the levorotatory isomer of amlodipine with pronounced pharmacological activity. This substance blocks slow calcium channels, as a result of which the penetration of calcium ions into the cells of the myocardium and smooth muscle of the vessels becomes impossible. Such an effect provides a decrease in the tone of the vascular wall, which, accordingly, leads to a decrease in blood pressure.

In addition, the drug has antianginal properties. Under its influence, the peripheral vessels expand. Since the medicine does not affect the heart rate, after decreasing peripheral vascular resistance, the load on the myocardium, as well as the muscle's need for oxygen, becomes less. The drug also removes spasm of smooth muscles from the coronary vessels, normalizing the flow of blood, and accordingly, and nutrition of the heart muscle.

It should be noted that Azomex does not exert a significant influence on the metabolism of carbohydrates and fats, so it can be used to treat patients with gout, diabetes and bronchial asthma.

After taking the pill rather quickly dissolves and absorbed in the digestive tract. By the way, meals do not affect the absorption of the drug. The maximum concentration of active substance in the blood is observed after about 6 to 12 hours. The drug acts relatively slowly, and therefore does not cause a sharp drop in blood pressure, which can also be considered an advantage, especially if it is a long-term therapy.

Bioavailability of the active substance is approximately 70 - 80%. The metabolism of the drug occurs in the liver - here it decomposes to inactive metabolites, which are then excreted from the body by the kidneys along with the urine. Half-life is quite long - 35 - 50 hours. In elderly people and patients with congestive heart failure, the drug is eliminated from the body for longer.

Main indications for use

In what cases is it expedient to take Azomex medicament? Indications for use are arterial hypertension, which occurs against the background of certain diseases of the cardiovascular system. In particular, the drug is often prescribed to people with ischemic disease. Tablets help with vasospastic angina pectoris, stable angina pectoris and angina Prinzmetal.

The drug "Azomeks": instructions for use

Tablets can be taken only according to the doctor's prescription, following all his recommendations, as otherwise side effects may occur. The specialist will also select the most appropriate schedule and dosage.

Tablets should be swallowed whole, without chewing and drinking with a sufficient amount of liquid. The effectiveness of the drug does not depend on the intake of food.

In what quantities should I take the remedy for hypertension "Azomex 2.5"? The instruction indicates that the initial dose is 1 to 2 tablets (not more than 5 mg of the active drug). If the effect of taking is absent, the dose of the drug can be increased. The maximum daily amount of active substance is 10 mg.

Are there any contraindications?

For many readers, it is interesting to ask whether all patients can take Azomex medicines (tablets). The instruction provides information that some contraindications to the drug still has.

To begin with, it must be said that it is not prescribed to people who have an increased sensitivity to any of the constituent components. In addition, tablets can not be taken with a decrease in pressure (if the systolic blood pressure does not exceed 90 mm Hg). Tablets have age limits - they are not used to treat children and adolescents under the age of 18. Also, the drug should not be taken by pregnant women and nursing mothers.

There are some other contraindications. In particular, the drug is not prescribed for patients with severe renal or hepatic insufficiency. The drug is not used for anuria, shock, acute myocardial infarction, cardiogenic shock. Contraindications also include severe aortic stenosis and unstable angina.

What side effects are possible?

Can there be any complications in patients who received the drug "Azomex" (tablets)? The instruction confirms that the probability of side effects exists, although, according to the reviews, such cases are rarely recorded.

So how can reactions lead to therapy?

• Against the background of taking the medicine, there may be some disturbances in the digestive system, in particular, pain in the stomach, nausea, dyspepsia, flatulence, stools, dry mouth. Very rarely develops gingival hyperplasia and anorexia. It is also possible to increase the activity of hepatic enzymes, disruption of the liver, difficulty in the outflow of bile.
• Sometimes there are disorders of the cardiovascular system, including arrhythmias, hypotension, dyspnea, flushing of the face, puffiness of the extremities.
• Side effects from the nervous system include dizziness, headaches, increased drowsiness, sleep disorders, depressive conditions, tremor, parasthesia.
• Some patients complain of pain and weakness in the muscles, convulsions.
• Allergic reactions are possible, including erythema, allergic dermatitis, hair loss.
• Other side effects include an increase in the daily amount of urine and frequent urination, gynecomastia, increased sweating, and violations in the sexual sphere.

All of the above violations are reversible and pass after the cancellation or reduction of the dose of the drug.

Overdose: signs and methods of treatment

Against the background of taking too large doses of this drug, excessive relaxation of the vascular walls of peripheral vessels is possible, which leads to hypotension. Sometimes there is a disturbance of the heart rhythm.

After taking too much of the drug recommended gastric lavage and reception of enterosorbents. In the presence of serious disorders patients are administered intravenously a solution of dopamine and calcium gluconate. Symptomatic therapy aimed at maintaining body functions is also prescribed.

How much are the pills?

Immediately it is worth saying that the price of these tablets varies in a very wide range. Here everything depends on the city and the pharmacy in which you make a purchase, as well as from the manufacturer. Packaging of 30 pieces with a dose of 2.5 mg costs about 200 rubles. The same number of tablets but with a dosage of 5 mg, costs about 370 rubles. In addition, there are also cheaper pharmaceutical products manufactured in India. Packing the same number of tablets from an Indian manufacturing company costs 120 (2.5 mg) or 180 (5 mg) rubles.

Effective analogues of the drug

For one reason or another, not every person suffering from increased blood pressure is treated with Azomex medicament. What to do in such cases?

In the modern pharmaceutical market, there are a lot of quality analogues that provide the same effect. For example, as a substitute, patients are often offered "Almodak", "Amlodipin", "Norvadin". With arterial hypertension, such drugs as "Semlopin", "Tenox" and "Vasodipin" are effective.

In any case, it is worthwhile to understand that only the attending physician who is familiar with the history of your illness can find a suitable remedy. Self-medication in such cases can be dangerous.

Feedback from specialists and patients

Today, many doctors prescribe the drug "Azomex" (tablets). Instructions for use here are simple enough, the number of contraindications is minimal, and side effects are rare, despite their impressive list. The medicine really helps to normalize blood pressure, and acts quickly enough. The undoubted advantage is that the drug is perfectly suitable for long-term treatment.

Patient feedback is also positive. Against the background of therapy, blood pressure comes back to normal, the unpleasant symptoms of hypertension disappear. The drug is convenient to use, and it does not cost too much - the price for some analogs is much higher.

The drug "Azomex" is released on prescription and it is not always easy to find it in the pharmacy - this is perhaps the only negative. Naturally, there are people who do not help the pill or even cause side effects. But the same can be said for almost any medicinal product, as it is impossible to accurately predict its effect on the human body. And, of course, do not forget that these pills are only part of the complex therapy for diseases of the cardiovascular system.