Analogues of "Mesatone" in Russia: list, description and instructions for use

In surgery and ophthalmology, until recently, the inexpensive preparation "Mesaton" of Ukrainian production was widely used. Now his supplies to Russia are stopped. Domestic manufacturers offer analogues of "Mezaton", which are mainly used in the form of drops for the nose and eyes. The choice of these in pharmacies is quite large and varied.

About Mezaton

So, "Mesaton": instructions for use, analogs, we will consider everything in order. The active substance of the drug is phenylephrine. When ingested, it narrows the blood vessels, increases cardiac contractions, expands bronchi, increases blood pressure.

It is used in case of collapse, shock conditions, blood loss, high blood pressure, intoxications, tachycardia. Also, the drug is used before performing operations with spinal anesthesia, in ophthalmology for pupil dilatation, in otolaryngology with rhinitis. Produced in ampoules, tablets, in the form of eye drops. Depending on the indications the drug is administered intravenously or intramuscularly, subcutaneously, orally, topically. "Mesaton" has contraindications: atherosclerosis, hypertension, myocarditis. Take care with hyperthyroidism, vascular spasms, people of advanced age. Possible side effects are headache and nausea. Previously, this drug was actively used in domestic medicine. Now, due to his absence from Russian pharmacies, Mesatone analogues are used, mostly in the form of drops for the eyes and nose.

Phenylephrine hydrochloride in ampoules

Produced in the form of a white powder, for intramuscular or intravenous administration diluted with water for injection. For the drug "Mesatone" analogs in ampoules are not so numerous, since basically it is used in the form of drops in the nose or eyes, cases of its injection are rare. Indications for use: acute arterial hypotension, vascular insufficiency, shock conditions (traumatic, toxic), local anesthesia (to reduce blood flow). It is forbidden to inject phenylephrine hydrochloride in arterial hypertension, cardiomyopathy, heart failure, atherosclerosis, cerebral arteries. In pregnancy, the drug can be administered only in extreme cases. The same applies to the lactation period.

During treatment, you need to monitor blood pressure and heart function. There are preparations for injections, which in their properties are similar to "Mezaton". Analogues in ampoules have other active substances, but similar effect on the body - ephedrine hydrochloride, adrenaline, noradrenaline.

"Irifrin": description

This is an analogue of "Mesaton" in Russia in terms of ophthalmology. The composition includes phenylephrine hydrochloride and auxiliary components. When it acts, the pupil dilator is dilated (muscle-expander) and the smooth muscles of the conjunctiva. As a result, the pupils dilate. The effect occurs within an hour, and lasts from two to seven hours, depending on the percentage of phenylephrine (2.5% or 10%). "Irifrin" is used for:

• Diagnosis of eye diseases that require dilated pupils;
• Prevention of posterior synechia (adhesions) and relaxation of exudation in the iris (iridocyclitis);
• The detection of a possible closed-angle glaucoma;
• Preoperative preparation of the pupil;
• Treatment of glaucomycyclic crises;
• Diagnosis of deep or superficial eye injection;
• Laser operations at the bottom of the eye;
• Red eye syndrome;
• Allergies and colds, to remove the swelling of the mucous eyes and nose.

Contraindications and side effects of "Irifrin"

Like Mesaton, analogs have their contra-indications, for Irifrin it is:

• Hypersensitivity to components;
• Glaucoma (narrow-angle, closed-angle);
• arterial hypertension;
• tachycardia;
• diabetes;
• aneurysm;
• Hyperthyroidism, thyrotoxicosis;
• Joint use with tricyclic antidepressants;
• Antihypertensive drugs, MAO inhibitors;
• Porphyria;
• Violation of the integrity of the eye or outflow of tear fluid.

The following side effects of the drug can be observed:

• conjunctivitis;
• Burning, irritation of the eye mucosa, lacrimation, increased intraocular pressure, blurred vision;
• Reactive miosis (typical for elderly people);
• Tachycardia, arrhythmia, other disorders of the heart, arterial hypertension;
• dermatitis;
• Rarely severe disorders occur in the form of collapse, myocardial infarction;
• Intracerebral hemorrhage.

"Vistosan"

Among the eye drops there are other analogues of "Mesatone", for example "Vistosan". Since its active ingredient is phenylephrine, the drug has the same effect when used, causing the pupil to dilate. Pharmacological action is similar to "Irifrin". Half an hour after hitting the eye in the moisture of the anterior chamber, parts of the iris pigment may be observed.

It is indicated for iridocyclitis, diagnosis of diseases, suspicion of glaucoma. A 10% solution is used to dilate the pupil in preparation for surgery, laser surgery and the treatment of glaucoma-cyclical crises. A 2.5% solution is treated with the "red eye" syndrome.

Contraindicated in allergies, glaucoma (narrow-angle or zakratougolnoy), violations of the cardiovascular system, hyperthyroidism, hepatic porphyria. It is undesirable to use people of advanced age. A solution of 10% is not used for children under 12 years of age, 2.5% - with a reduced body weight. It is not desirable to use during pregnancy and lactation.

Side effects of "Vistosana"

Analogues like phenylephrine, like Mesatone, have similar side effects: blurred vision, irritation, burning, lacrimation, rarely reactive miosis, cardiac dysfunction (tachycardia, arrhythmia, in rare cases, myocardial infarction).

For ophthalmoscopy, a solution of 2.5% to 1 drop is used, if necessary, the effect is repeated after one hour in the same dosage. With iridocyclites - 1 drop 2-3 times a day of a solution of 2.5 or 10%. For the treatment of glaucoma-cyclical crises use a solution of 10% 2-3 times a day.

"Neosinephrine-PIC"

Another ophthalmologic analogue of Mesatone in Russia is Neosinephrine-PIC. The active ingredient is phenylephrine hydrochloride. Available in the form of 5% and 10% solutions of drops for the eyes. To diagnose the diseases, the dose used is 1 drop of 5% solution, after an hour, a repeat is allowed for a longer effect. If the pupil is dilated enough, 10% solution is allowed.

In case of an overdose, nervousness, sweating, dizziness, tachycardia, vomiting, and a sense of anxiety may occur. Pharmacological properties are the same as in analogues containing fenidephrine.

"Adrianol"

The Russian analogue of "Mezaton" in the treatment of the common cold is "Adrianol". The form of the release is nasal drops of plastic bottles-droppers. The active components are tramazoline hydrochloride and phenylephrine hydrochloride. Has a vasoconstrictive and anti-edema effect on the nasal mucosa when applied topically. As a result, nasal breathing is facilitated, pressure in the middle ear and sinuses of the nose decreases. Due to the viscous consistency has a long action. It is indicated for use in acute and chronic rhinitis, sinusitis, and also as an auxiliary preparation for operations and diagnostics for the removal of edema.

Contraindications: hypersensitivity to components, glaucoma, kidney disease, arterial hypertension, thyrotoxicosis, atherosclerosis, ischemia of the heart, pheochromocytoma, atrophic rhinitis. Apply 1-3 drops 4 times a day to adults, children from one to five years - 2 drops 3 times a day. The duration of the course is not more than seven days. Rarely occur side effects in the form of burning and dry mucous.

"Nazole Kids"

Analogues of "Mesatone" in otolaryngology, created specifically for children - "Nazol Baby" and "Nazole Kids." The main active substance is phenyeprin hydrochloride. Additional components are eucalyptol, glycerol, macrogol, sodium hydrogenphosphate, edetate disodium, potassium dihydrogen phosphate, benzalkonium chloride, purified water. Difficult breathing is facilitated by the action of phenylephrine - a reduction in smooth muscles, narrowing of the vessels, a decrease in mucus.

The remaining components eliminate discomfort, moisturize the mucous membrane, have an anti-inflammatory effect. It is prescribed for the common cold, infections in the upper respiratory tract, colds and flu, allergic rhinitis, sinusitis. "Nazole Kids" is produced in the form of a spray, the allowable dosage is 2-3 sprays every 4 hours. It is used for children from the age of six.

"Nazel Baby"

In the preparation "Mezaton" analogues and substitutes are produced even for infants. This "Nazol Baby" in the form of drops for the nose with active substance phenylephrine in a 0.125% solution. This content of the component provides safety for the tender mucous baby.

Additional constituents - disodium salt, benzalkonium chloride, ethylenediamine tetraacetic acid, sodium phosphate disubstituted, polyethylene glycol, potassium phosphate monosubstituted, glycerol, purified water. Has an antimicrobial effect, without disturbing the receptor perception of infantile mucosa. It is prescribed for cold and viral diseases, pollinosis, allergic rhinitis.

In the first year of life, the drug is applied 1 drop every 6 hours. For children from 1 year to 6, the dose increases - 2 drops every 5 hours. Duration of the course is no more than three days. Contraindicated use of women during pregnancy and lactation. This is the most convenient and safe for the drug "Mesaton" analogs. The price in pharmacies is within 200 rubles.

Remedies for colds

One-component preparation "Mesaton" analogs went around in the field of use. Medicines containing phenylephrine in combination with other active substances are used during the cold and the flu to eliminate the characteristic symptoms. So, for example, "Maksikold", is issued in the form of tablets or powder for the preparation of a solution taken orally.

The active ingredients are phenylephrine hydrochloride, paracetamol and ascorbic acid. It is used for chills, fever, nasal congestion, headache and muscle pain for colds. Other similar preparations of the Russian production are Prostudox, Feniprex-C, Flukomp.