"Vals" (tablets): instructions for use. Preparation "Valz": analogues, reviews, prices

What is the use of the drug "WALZ" (tablets)? We will discuss this further. In the materials of this article we will tell you about whether this medicine has analogs, side effects and contraindications. Also, patients' reviews and instructions on the use of the drug will be described.

Composition, description and packaging of medicinal product

What is the composition of the drug "Vals"? Tablets contain an active substance such as valsartan. Also in their composition are additional components in the form of talc, croscarmellose sodium, microcrystalline cellulose, lactose monohydrate, magnesium stearate, povidone K29-32 and silicon dioxide.

The drug in a dosage of 40 mg is film-coated, has a yellow color and an oval biconvex shape. On one side of the tablets there is an engraving "V", and on the other side side risks. Also on sale comes the drug in pink (80 and 160 mg).

The medication in question, the "Valse" tablet, is packed in blisters, which are placed in cardboard boxes.

Pharmacological features

What is a "Vals" medication? Tablets are prescribed as an antihypertensive and a peripheral vasodilator. This drug is able to block AT1 receptors of angiotensin II, but it can not inhibit ACE.

Under the influence of the active substance of the drug does not change the content of glucose, total TG, Xc and uric acid in the blood.

How quickly the "Vals" medication begins to work? The tablets are absorbed fairly quickly. After 2 hours after taking (maximum after 5-6 hours), they begin their action.

The effect of taking the drug "WALZ" usually persists throughout the day. With regular therapy, the maximum indices of blood pressure reduction are observed only after 2-4 weeks. If the patient abruptly stops treatment, then withdrawal syndrome does not arise.

Pharmacokinetic properties of tablets

Is the drug "Vals" (pills) rapidly absorbed? Instruction for use says that after taking the remedy inside, its fairly rapid absorption is noted. Bioavailability of the drug is approximately 23%. The linear character of the pharmacokinetic properties of valsartan is noted.

The active substance of the drug has a sufficiently high level of binding to plasma proteins. This indicator varies between 94-97%.

If the "WALZ" tablets are taken repeatedly, the kinetic indices will not change in any way. With a one-time admission of funds a day, the patient experiences a small cumulation of valsartan. In the blood there are insignificant concentrations of inactive hydroxy metabolite.

After taking the medicine inside about 83% of the active substance is released through the intestine (with bile), and another 13% in the unchanged form is excreted by the kidneys.

Indications for use

What is the purpose of the drug "Vals"? Tablets from pressure in hypertension act very quickly and effectively. In addition, they are taken with a chronic form of heart failure (in complex treatment), as well as to increase the survival rate of people who have experienced acute myocardial infarction.

Contraindications

When should I not take the drug "Vals" (pills)? Feedback from specialists indicates the following contraindications:

• Kidney failure (occurring in severe degree), including during the passage of hemodialysis;
• Impaired liver function, resulting from obstruction of the biliary tract;
• Period of pregnancy;
• Impaired absorption of galactose or glucose, lactose intolerance, galactosemia;
• Breastfeeding;
• Age to 18 years;
• Intolerance of the components of the drug.

It should also be noted that the preparation "Valz" is used with extreme caution in obstructive hypertrophic cardiomyopathy, arterial hypotension, primary hyperaldosteronism, stenosis of the renal arteries, hyperkalemia, mitral and aortic stenosis, and hyponatremia.

The drug "Vals" (tablets): instruction for use

Before taking the medication, the patient should always read the instructions. Also it is necessary to consult with the attending physician.

How should I take Wals 80? Tablets in this dosage are prescribed for patients with hypertension. Take medication should be taken orally, once a day, regardless of food intake.

After the beginning of treatment, the hypotensive effect of the "Valz" agent begins to appear in the first 2 weeks. The greatest effect of the drug is observed after about a month.

If the daily dosage of the drug in 80 mg does not have the proper effect, then it is doubled.

In the process of therapy, the patient can be prescribed and another antihypertensive drug, in particular diuretic.

As with heart failure should take "Vals" (pills)? The instruction attached to the drug states that with this diagnosis, especially in chronic form, the patient needs to take 40 mg of the drug twice a day. If this dosage is ineffective, then gradually increase it to 80 mg with the same multiplicity.

With a good state of health, the dose can be increased to 160 mg twice a day. However, at least two weeks must pass from the start of treatment to the time when the maximum dosage is taken.

The maximum amount of medication per day is 320 mg. In this case, the dose of the drug "WALZ" should be divided into two steps. When administered together with diuretics, it is sometimes reduced.

In the event that the patient underwent myocardial infarction and his hemodynamic parameters are stable, the drug treatment begins no later than 12 hours after the attack.

The first dose should be 20 mg twice daily. Gradually, it is increased to 40 mg, and then to 80 mg. By the end of the third month of treatment, the daily dose of the drug should be already 160 mg (divided into 2 divided doses). In this case, increasing it, it is necessary to take into account the tolerability of the drug.

Signs of an overdose

What symptoms of overdose may occur if the "Valz" preparation is not properly administered? In such cases, a person has a strong drop in blood pressure. Such conditions often cause collapse and loss of consciousness. It is urgently necessary to wash the stomach and give the patient activated charcoal. Also, an overdose of a patient intravenously injected 0.9% solution of sodium chloride.

Drug Interactions

Taking the preparation "Valz", it should be taken into account that its pronounced interaction with other medicines is not noted. But if the patient simultaneously takes other antihypertensive drugs and diuretics, then the antihypertensive effect of valsartan can significantly increase.

The risk of developing hyperkalemia increases with the joint intake of the tablets under consideration with potassium-sparing diuretics, potassium preparations and agents that increase its content in blood plasma.

When using a drug with NSAIDs, its antihypertensive effect decreases.

It should also be noted that there is evidence of toxic effects and a reversible increase in the concentration of lithium in the blood in the treatment of "Valz" tablets and ACE inhibitors.

According to the instructions, it is allowed to combine the drug in question and other drugs that are used to treat heart failure. However, this remedy can not be used simultaneously with ACE inhibitors and beta-blockers.

special instructions

What should the patient be informed before appointing him a medicine "Vals"? Tablets from pressure (feedback on them will be presented further) should be taken only after the level of fluid and electrolytes in the patient's body is restored. To do this, it is recommended to reduce the dose of diuretics.

If a person has Renovascular hypertension, then it should be ensured that he regularly checks urea and creatinine levels in the blood.

During therapy with the drug "Valz", especially in chronic heart failure, the patient can decrease blood pressure. Therefore, a constant monitoring of this indicator is extremely important.

When treating this medication, there may be changes in the functioning of the kidneys.

The drug "Vals" (tablets): analogues and price

Synonyms of the drug under consideration are the following medicines: Valsafors, Valsartan, Diovan, Valsakor, Tantordio, Nortivan, Zentiva, Tareg.

Also there are its analogues, similar in mechanism of impact. They include such drugs as "Aprovel", "Brozaar", "Bloktran", "Zisakar", "Lozartan", "Irsar", "Lakea", "Cardosten", "Teveten", "Macleodz" and others.

The price of the medicine we are considering is not very high. For 28 tablets (40 mg) you will have to pay about 150 rubles.

Patient Reviews

Most patients leave positive feedback about the drug "Vales". They argue that this medicine is an effective tool for reducing blood pressure.

The action of the tablets begins to appear very quickly. They can reduce the blood pressure, thereby improving the overall condition of the patient.

In patients' reviews, there is also such a positive moment: when there is a sharp stoppage of treatment with the drug, there is no withdrawal syndrome.