Triptans from migraine. Triptans: drugs, prices

Migraine is a problem for many patients. Almost every person experiences pain in the head area at least once in a lifetime. As a rule, they are accompanied by dizziness, nausea, vomiting, as well as numbness, tingling and weakness in the extremities, photo and phonophobia. After the attack, patients complain of increased fatigue, lethargy and drowsiness. Sometimes there are cases when the disease is so neglected that only the triptans of the headache can help the patient. It is worth noting that migraine is a disease of women, as they are more susceptible to this pathology than men. Approximately 10-18% of the adult population is diagnosed with migraine.

The problem of headache is familiar to every person

Most people do not seek qualified help from doctors, but try to cope with the disease on their own, while taking analgesics. It must be said that this approach does not help, but only aggravates the course of the disease. Uncontrolled use of analgesics can provoke the development of a drug-induced chronic headache. Therefore, it is not surprising that there are a lot of questions about which headache pills are the most effective.

Completely cured of migraine is unrealistic, but you can improve the quality of life with the help of special medications prescribed by a neurologist. To date, there is a huge amount of funds for migraines, which are quite effective both during the attack and during the inter-attack period. Next, we will consider in more detail the preparations for migraine: a list of remedies for stopping and intercostal therapy. It has been proven that tryptans are the most effective medicines to eliminate severe headaches. With the preventive purpose the following groups of drugs are appointed:

• Β-blockers;
• Antidepressants;
• Antiemetics;
• Water-soluble B vitamins;
• Calcium blockers;
• Anticonvulsants.

All qualified pharmaceuticals should be administered by a qualified technician.

Why does the headache?

Before you understand how tryptans from a headache, the price of which depends on the manufacturer, you need to understand the mechanism of the emergence of pathology. Headache develops due to irritation of the receptors of the meninges and cerebral vessels. With excessive stretching and overflow of blood vessels, especially veins in the hypotonic state, severe pain develops, which can be eliminated only with the help of special pharmaceutical agents. Many researchers who have been looking for a long time drugs for the treatment of migraines, came to the conclusion that tryptans - the best way to eliminate this pathology.

Properties of triptans

The action of drugs is aimed at narrowing the dilated vessels of the brain. Triptan is a drug that affects the nuclei and receptors of the trigeminal nerve, which in turn reduces the sensitivity of the pain threshold. Triptans are modern antimigraine drugs, which have quite high selectivity for the blood vessels of the dura mater encephali and insignificant relative to the peripheral and coronary vessels and vessels.

Presented medicines effectively stop pain at the level of the spinal cord of the trigeminal nerve. In addition to all of the above, tryptans are drugs that allow not only to reduce the frequency of relapses of pathology, but also to eliminate associated clinical manifestations of it (for example, nausea, vomiting, sound and photophobia).

The main advantages of triptans

In their pharmacological properties, a high rate of obtaining the result is established. Literally after half an hour, symptoms of a positive effect of the drug on the patient's body are observed. The therapeutic effect persists throughout the attack of migraine. In the vast majority of patients, the headache does not recur.

Nowadays, scientists have proved that if you find signs of an attack, you should immediately take triptans from a migraine. Previously, there was a theory that migraine attacks should be treated in stages, starting with simple medications.

Medications for migraine: a list of the most popular medications

The group of triptans includes the following drugs:

• The Zomig.
• "Amigrenin."
• Sumatriptan.
• "Imigran".
• Relpaks.
• "Trimigrene."
• "Sumygamren".
• "Rapimed".
• Almotriptan.
• "Naramig".
• Naratriptan.
• "Frovatriptan".
• "Zolmitriptan".

The effects of drugs for each patient can be strictly individual, so in order to verify the effectiveness of one or another medication, doctors recommend trying it in three migraine attacks. Tryptamine group of drugs is characterized by high bioavailability, they easily and quickly overcome the blood-brain barrier, effectively stop migraine attacks even in the pain phase. These medications should be administered to patients with moderate and severe illness severity.

Recommendations for use

Quite often we hear the same question: which headache pills are better? Experimental studies have shown that the most effective remedy for the removal of migraine symptoms are triptans. It is best to take tryptans from a migraine if the first signs of an attack are detected. The maximum analgesic effect is observed already two hours after taking the medicine. Before taking the drug, carefully read the instructions and consult your doctor. It is very important not to overdose the medication. Triptans from migraine are not recommended to be used together with antibiotics, antifungal, antiviral agents, and also in conjunction with antidepressants.

To achieve the desired result, patients should adhere to the following recommendations for the administration of triptans:

• With mild and moderate headache, take 1 tablet (or one dose of the spray);
• The second dose of the drug is taken no earlier than 2 hours later;
• Within a day, do not take more than two doses;
• Tryptans are not recommended for taking more than two days a week.

During the period of treatment, the tyramine-containing products should be excluded from their diet:

• cocoa;
• chocolate;
• Beans;
• Eggs;
• celery;
• citrus;
• nutritional supplements;
• Cheeses;
• Tomatoes;
• Nuts;
• Alcoholic beverages.

Do not also eat cold food.

When migraine occurs, tryptane, the price of which will be listed below, can be used with other medications, such as domperidone or metoclopramide.

Side effects

When an overdose of the drug, patients face the following problems:

• dizziness;
• anaphylactic shock;
• Feeling of constraint;
• nausea;
• Sensation of heat;
• Infarction of the spleen, intestine;
• Vomiting;
• Dry mouth;
• Myalgia;
• abdominal pain;
• drowsiness;
• Burning sensation on the skin;
• Angioedema;
• tachycardia;
• hives;
• Polyuria;
• Muscle weakness;
• Decrease attention;
• Sensitivity disorders;
• Hemorrhagic diarrhea;
• Frequent urination;
• Spasm of the coronary vessels.

Despite all this, tryptans from migraine are a quick-acting medicine. If the dosage and the frequency of medication are observed, the risk of side effects is minimal. In general, all the tryptans are carried by the body normally. Side effects, if manifested, are moderately expressed and pass spontaneously without medical intervention. The main disadvantage of triptans is their cost. Unfortunately, not all patients can afford such a medicine.

Contraindications

Tryptans from migraine are not recommended for use in the following cases:

• stroke;
• Angiospastic angina pectoris;
• pregnancy;
• Disorders of cerebral circulation;
• Breastfeeding period;
• Coagulopathy (bleeding disorders);
• adolescence;
• Pathology of the cardiovascular system;
• Hypersensitivity to bioactive substances of the drug;
• Uncontrolled arterial hypertension;
• Arrhythmias;
• Liver and kidney disease;
• atherosclerosis.

Before prescribing certain triptans, the attending physician should identify risk factors for the development of atherosclerosis. To such factors it is possible to carry the following:

• diabetes;
• Post-menopausal period in women;
• smoking;
• hypertension;
• obesity;
• High level of pathological cholesterol in the blood;
• Age over 40 years in men;
• Genetic predisposition to a heart attack.

Some patients who are at risk should receive their first dose of tryptamine under the supervision of a specialist and under ECG monitoring.

Treatment of migraine

There are general therapeutic principles for the treatment of a disease that justify themselves in most cases:

• It is necessary to start treatment with the use of analgesics or a combination thereof (including non-steroidal anti-inflammatory drugs);
• If the use of analgesic did not give a positive result, then after 45 minutes, tryptane should be taken;
• If the tryptane was ineffective, then the next attack should use another drug from the tryptane group;
• In an atypical attack of headache, non-steroidal anti-inflammatory drugs should be used.

The use of modern means for the treatment of migraines, created on the basis of triptans, helps to alleviate the life of many patients. Do not forget that you can take these medications as prescribed by the doctor and only if the diagnosis is established. There are situations when triptans and other nonspecific analgesics do not give the desired result and do not eliminate the pain syndrome. In this case, physicians, as a rule, prescribe a comprehensive therapy with the use of anticonvulsant medications, as well as beta-blockers. These drugs include the following drugs:

• Penbutolol.
• "Nadolol".
• Betaxolol.
• Topiramate.
• Neuronthin.
• "Phenobarbital."
• Timolol.
• Propranolol.
• "Labetanol."
• Bellataminal.
• Metoprolol.
• Topamax.
• "Acebutalol."

How to reduce the frequency of seizures?

To reduce the frequency of migraine attacks, patients should adhere to the following rules:

• Eat regularly;
• Exclude from your diet foods and beverages that provoke seizures (beer, chocolate, cheeses, champagne, citrus, red wine);
• Stop smoking;
• As long as possible in the fresh air;
• Avoid stress;
• Do sports (ideal - swimming);
• Avoid long trips by bus, boat, car.

Tryptans from a headache: the price

Triptans are produced in various dosage forms: injection solutions, nasal spray, tablets, rectal suppositories. The cost of the drug affects the form of release, dosage, the number of tablets in the package. As a result, the price of these drugs fluctuates in a wide range - 150-1500 rubles per package.