The preparation is Progestogen. Instructions for use

The preparation "Prozhozhezhel" instructions for use refers to the clinical and pharmacological group of medicines used externally for the treatment of mastodynia.

It is produced in the form of a one-percent colorless gel (visible particles in it are absent), which smells of alcohol.

Active active substance of the drug is natural micronized progesterone. Among the auxiliary - trolamine, distilled water, ethanol, carbomer 980, octyldodecanol, castor oil.

The drug "Progestogen", the instruction for use informs, has a therapeutic effect due to the action of progesterone. This substance blocks the receptors of estrogens, thereby reducing compression in the milk ducts, as well as improving the absorption of fluid from the tissues. In addition, prolactin receptors are blocked in the breast tissue, which reduces lactopoiesis.

The medicine "Progestogel", the instruction for use contains this information, when used locally, it determines the high content of the main active substance in the field of application. In this case, there is no systemic effect and no side effects occur.

The drug "Progestogen", the use of which relieves mastodynia, inhibits tubular reabsorption and increases cellular filtration. This prevents fluid retention when converting the secretion of the glandular component in the mammary glands.

The transdermal type of drug use makes it possible to influence the vasculature and glandular epithelium. Due to this, permeability of capillaries decreases, swelling of tissues in the mammary gland, signs of mastalgia disappear.

The medicine "Progestogel", the instruction for its use recommends the transdermal way of use, is able to reach the tissues of the diseased organ, without exerting undesirable effects on the body and not disintegrating in the liver.

Absorbability of the main active ingredient with appropriate application is ten percent of the applied volume. The most complete absorption into the skin is observed one hour after the use of the drug. At the same time, the level of hormones does not change.

According to studies, the drug in question is mostly excreted in urine (up to sixty percent), a small amount of it leaves the body along with bile.

Indication for the use of this tool is mastodynia, the occurrence of which is due to the use of contraceptives (oral), the presence of premenstrual tension syndrome, mastopathy, pregnancy. In addition, the drug is used to treat fibrocystic mastopathy.

The medicine "Progestogel". How to apply?

A small amount (about two and a half grams) of the gel is applied with the help of a dose applicator to the problem areas until the drug is completely absorbed. The procedure is repeated daily several times a day, or from the sixteenth to the twenty-fifth day of the menstrual cycle (its second phase).

The course of treatment can last up to three cycles. Repeatedly it can be carried out only in consultation with a specialist.

Possible side effects: the manifestation of various allergic reactions - edema of the lips or neck, the occurrence of fever, erythema in the field of applying gel, headache and nausea. Extremely rare metrorrhagia, decreased libido, a painful sensation in the mammary glands.

The drug is contraindicated in nodular forms of fibrocystic mastopathy, tumors or tumorous formations of unknown origin, monotherapy of genital canal, in the second and third trimester of pregnancy, as well as hypersensitivity to the components that make up the Progestogel drug.