HealthDiseases and Conditions

The norm of ALT and AST in the blood and the reasons for the increase in indices

Since recently, almost all cities of the Russian Federation have been screening the population, which allows early detection of a number of diseases and thereby reduce the risk of premature mortality.

The main indicators of liver function

Diseases of the liver are the most frequent and dangerous because of the asymptomatic course. At the stage of screening, along with other studies, the patient is assigned a blood test for biochemistry, the main indicators of which are aimed at determining how the liver functions. The norm of ALT and AST in the blood is completely dependent on the work of the most important parenchymal organ - the liver, which performs such functions as:

  1. Detoxification is the elimination of toxic substances and poisons from the body.
  2. Synthesis of protein.
  3. The production of biochemical substances necessary for the organism.
  4. Storage of glycogen - a polysaccharide, which is necessary for the full vital activity of the body.
  5. Regulation of biochemical reactions of synthesis and decomposition of most microparticles.

ALT and AST are enzymes that are produced mainly by the liver and are involved in all its biochemical reactions.

The norm of ALT and AST in the blood

The norm of ALT and AST in the blood depends on many factors, including sex and age. In connection with the lack of a single standard in practically every medical institution, the laboratory sets its own ALT and AST norms, for this reason, with all the analyzes it is necessary to contact the doctor who supervises you, and not to engage in self-interpretation. The normal range is:

  1. The norm of AST in the blood from 5 to 40 IU / liter.
  2. The norm of ALT in the blood for women: from 7 to 35 IU / liter.
  3. The norm of ALT in the blood for men: 10 to 40 IU / l.

The norm of ALT and AST in the blood and analysis of the main causes of the increase

A slight increase in ALT and AST in the body often occurs asymptomatically, but it indicates a malfunction in the liver.

The most likely cause of increased liver enzymes in the blood are:

  1. Fatty hepatosis.
  2. Drug reaction.
  3. Injury.
  4. Increase in ALT and AST as a consequence of diseases of other organs (autoimmune thyroiditis, pancreatitis, mononucleosis).
  5. Diffuse liver lesions that can be caused by alcohol, drugs and (or) the effect of the virus.
  6. Metastases or neoplasms in the liver.

The earliest symptoms of increasing ALT and AST are:

  1. Increased fatigue and weakness.
  2. Decreased appetite and, as a result, weight loss.
  3. Itching itch.
  4. Insomnia, nervousness.

Late symptoms of increased ALT and AST:

  1. Edema of limbs, ascites (presence of free pathological fluid in the abdomen).
  2. Skin covers, proteins, mucous become yellow.
  3. Change of color of urine - "urine of color of dark beer", discoloration of feces.
  4. Increasing symptoms of intoxication (poor health, weakness, nausea, hyperthermia, etc.).

Methods of additional diagnostics:

  1. Ultrasonic diagnosis of the abdominal organs, if necessary - the thyroid gland.
  2. Blood test for markers of hepatitis B, C.
  3. Clinical blood test.
  4. Blood test for hormones and antibodies of the thyroid gland.
  5. If necessary, liver biopsy.

We reduce AST and ALT

The rules, observing which, a person can reduce the indicators of AST and ALT, such:

  1. Eat as much as possible fresh vegetables and fruits, as well as brown rice, - they contain fiber.
  2. Drink green tea and herbal teas, which include the root of a dandelion, milk thistle, burdock root.
  3. In your diet should be foods that contain vitamin C.
  4. Observe drinking regimen at the rate of 30 ml of liquid per 1 kg of weight.
  5. Do respiratory gymnastics.
  6. Take a contrast shower.

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