The drug "Mazepam": instructions for use. Reviews about the drug "Mezapam"

In what cases can the drug "Mazepam" be used? The price, indications and instructions of this medicine are presented below.

Form, composition

"Mazepam" - tablets are round, flat-cylindrical. Their main substance is mesapam. As for the additional components, they are starch, lactose monohydrate and calcium stearate.

Effect of the drug

What are Mazepam tablets? Instructions for use asserts that this is an anxiolytic remedy, or a so-called tranquilizer. This medication is a benzodiazepine derivative. It exhibits anxiolytic, antiepileptic and miorelaxing properties, and also has a weakly expressed timoleptic effect.

The hypnotic and sedative effect of this drug is observed to a lesser extent than the standard benzodiazepine tranquilizers. In this regard, the drug in question refers to a kind of group of "daytime" tranquilizers.

This agent interacts with the receptors (benzodiazepine) limbic system, as well as with the activating ascending brain stem (head) formation. Thanks to him, the opening of the chlorine canals, which eventually leads to an increase in the slowing effect of GABA in the central nervous system.

It should also be noted that the drug "Mazepam", the instruction for which is described below, helps to eliminate anxiety, psychoneurotic stress, feelings of fear, excessive fussiness and general motor excitement. In addition, it has a stabilizing effect on the vegetative NS, restores emotional behavior and a critical assessment of one's own illness.

Kinetics

What pharmacokinetic parameters are characteristic for tranquilizer "Mazepam"? Instructions for use asserts that after ingestion, the tablet is rapidly absorbed in an amount of 50-75%. Their highest concentration in the blood is reached after two hours. Binding to plasma plasma proteins is 99.7%.

Metabolites of this agent are excreted by the kidneys and through the intestine for 20-175 hours.

Indications

Tablets "Mazepam", reviews of which you will find further, are used for irritability, neuroses, agitation and nervous tension. Also, this remedy is recommended for use in withdrawal symptoms in people who suffer from alcoholism, to prevent migraine and climacteric syndrome.

In pediatrics, this drug is used with increased excitability of the child, mental lability and "school" neuroses.

Contraindications

This drug should not be taken during pregnancy, myasthenia gravis, nighttime apnea, intolerance to medazepam, renal and hepatic pathology, breastfeeding and various forms of dependence (narcotic, alcoholic). In addition, this drug is contraindicated in cerebellar ataxia, organic pathology of the NS, intraocular hypertension, respiratory failure and spinal ataxia.

Tranquilizer "Mazepam": instructions for use

Tablets "Mezapam" are taken three times a day, starting with a small dose of 5 mg. Gradually, the amount of this drug is adjusted to a level of 30 mg per day. In rare cases, it is permissible to take 40 mg of the drug per day.

For outpatient treatment, the following treatment regimen is recommended: 5 mg of medication in the morning and 10 mg in the evening. In hospital conditions, the maximum daily dosage of this agent can be increased to 60-70 mg.

The duration of therapy with this remedy is 2 months (no more). After 30 days, the course can be repeated.

Occasional phenomena

This tool can cause the following effects:

• Dyspeptic disorders, increased bilirubin, AST, ALT, dry mouth;
• Heart palpitations, falling blood pressure;
• Deafness, disinhibition, headaches, anterograde amnesia, accommodation parasite, depression, dizziness, dysarthria, loss of strength, loss of orientation, ataxia, aggressiveness, confusion;
• In people with COPD, when taking high doses of the drug, alveolar hypoventilation is noted;
• With airway obstruction and brain damage, the respiratory center is depressed.

Special Recommendations

The use of Mezapam tablets may contribute to impaired attention and memory, as well as impaired learning.

Together with this tool is unacceptable consumption of ethanol-containing beverages.

It is recommended gradual withdrawal of the drug in the treatment of withdrawal symptoms.

Long-term therapy can form a drug dependence on medozepam.

Price and reviews

The cost of the tranquilizer in question is about 150 rubles.

The patient's testimonies indicate a fairly good tolerability of the drug, with all the prescriptions of the doctor and the dosing regimen. Although in isolated cases this remedy nevertheless contributes to the development of drug dependence, decreased potency, delayed urination, paradoxical reactions, allergic reactions, chest pain and dysmenorrhea.